Tag: diseases

10 facts about Fucoxanthin (FX): A promising natural supplement 🙌

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Flavonoids, antioxidants, anti inflammatory, Fucoxanthin, chlorophyll, algae, seaweed, seafood, healing, health, Infection,inflammation, Inflammation, diseases, environmental damage, health issues, nature, Obesity, weight loss, Supplement, wellness

1. Fucoxanthin (FX), a brown pigment, is derived from various seaweeds and algae. It helps in algae photosynthesis and photo-protection in the aquatic environment. Several studies have shown that this phytochemical can be a potential source of nutritional and health benefits against various diseases like diabetes, obesity, cancer and many infectious diseases. Recent findings have shown that it has various properties like antimicrobial, antioxidant, anti-inflammatory, anti-obesity, anti-diabetic, and hepato-protective effects. Therefore, because of its highly potent effects of prevention of obesity related diseases, anti-cardiovascular, tumour inhibition and health benefits to bones, skin, eyes and liver, this pigment has been a promising pharmaceutical asset.

2.Molecular Structure: The unique molecular structure of FX is similar to that of Beta carotene and has the allenic bond. Out of 700 naturally occurring carotenoids, only 43 of them belong to the allelic group, and FX is one of them. Therefore, there is growing interest in the pharmacological activity of this carotenoid, which can be a great potential source towards the prevention of various physical illnesses. FX is mainly found in micro-algae rather than macro-algae. Among the three kinds of micro-algae, that is green, red and brown algae, FX is in higher concentration in brown algae.

3. Multi-functional: Research has already shown that FX has a tremendous amount of health benefits because of its unusual molecular structure. The multi-functional benefits are namely, anti-oxidant, anti-microbial, anti-inflammatory, anti-allergic, anti-malarial and anti-helminthic. Apart from these activities, FX helps to correct the imbalance of lipid metabolism, which is created by a fatty, unhealthy diet. It has a positive impact on fatty acid oxidation, lipolysis, and bile acid synthesis and lowers the level of free fatty acids.

4. Anti-obesity effects: This brown pigment is a promising asset for lowering weight naturally. Obesity has been one of the main risk factors of many chronic and serious health issues like diabetes, heart diseases, high blood pressure, atherosclerosis, fatty liver, high cholesterol, infertility and many cancers. FX lowers the free fatty acids, inhibits lipogenesis, promotes beta-oxidation, bile synthesis, and influences enzymes which are essential for lipid metabolism. As a result, fat accumulation in the liver and adipose tissues is lowered, reducing cholesterol and triglyceride concentration.

5. Liver: Studies have shown that FX has hepato-protective effects. In case of fatty liver diseases, it can help in reducing the accumulation of lipid in liver cells, stimulate Beta-oxidation of hepatic fatty acids and lower the hepatic enzyme activity for fatty acid synthesis. Several animal studies have shown promising results of reducing lipid and triglyceride concentrations in the liver.

6. Inhibitory effect on cancers: Several studies on different cancers have shown that FX can scavenge free radicals and make it a potential modulator of carcinogenesis. FX has shown promising outcomes in different animal studies of inhibiting apoptosis and hindering the tumorigenesis in different types of cancers like lung cancer, colon cancer, breast cancer, liver cancer, gastric cancer, lymphoma and leukaemia. They behave as angio-modulators in cancer therapy.

7. Metabolism of FX: Because of its wide range of health benefits and potential role in the prevention of chronic illnesses, it has been a promising compound in pharmacological uses both individually and in synergy with other compounds. FX is a carotenoid which is mainly absorbed in the small intestine, similar to fats and fat-soluble vitamins. Studies have shown that consumption of this brown pigment orally does not show abnormal changes in organ tissues; therefore, it is safe for human use.

8. Food sources of FX are various species of seaweeds like Wakame, Arame, Kombu, Hizika and Laminaria digitata. Some other natural sources are microalgae like diatoms. Marine invertebrates like mussels, oysters, and clams also contain a small amount of FX. Predominantly, FX is present as a rich source in brown seaweed compared to other pigments like chlorophyll and xanthophylls.

9. As a supplement: Animal studies have shown the safe use of FX and that it has no adverse effect on the body. Therefore, it has been widely used as a supplement for its wide range of health benefits. It is used as tablets, capsules and soft gels usually labelled as Fucoxanthin or “brown seaweed pigment” While the bioavailability can be low in case of human consumption, its absorption can be increased when consumed with lipids and edible oils. Dosage can vary from 3-5 mg per day.

10. Side effects: FX has no adverse effects and no toxic accumulation in the vital organs of the body in case of animals when consumed in higher doses. Therefore, it is considered safe for human consumption. It is considered safe for vital organs like the liver, kidney, spleen and gonads when consumed moderately in humans. Further research on humans is still required for more clarification. It is always advisable to consult a Physician before introducing FX as a supplement when there is a pre-existing medical condition.

Thanks for reading.

Peace and love 🙏

10 facts: Gut-brain impact on sleep-wake cycle 😴

by drjurisharma, posted in Blog, brain, Gut brain axis, gut health, brain, sleep pattern, sleeping habits, insomnia, sleep deprivation, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, meditation, inflammation, disease, physical health, mental health, wellbeing, self healing, wellness

1. The gut is known as the “second brain” as there is a 2 way connection between the brain and the gut via the vagus nerve. The gut microbiome produces neurotransmitters that can travel and send signals through the nervous system, affecting our mood, behaviour, emotions, and sleep. The gut and brain also send signals through hormonal pathways and the immune system.Therefore, the gut-brain axis plays a crucial role in overall well-being, and any disruption to this axis can lead to issues such as disturbances in gut health, neurological disorders, inflammation, and sleep disturbances.

2. Through the gut-brain axis, there is a mutual continuous communication between the brain and the gut. The gut microbiome produces a considerable amount of neurotransmitters and hormones like melatonin, which influence the circadian rhythm and mood. Both the sleep cycle and gut microbiota are influenced by factors like daylight, stress and diet. Hence, if there is unhealthy gut microbiome, there will be disruption in the sleep-wake cycle, while poor sleep will lead to disturbances in the gut microbiota.

Gut microbes

3. Inflammation: Poor sleep can cause disturbances in gut health, which will lead to a pro-inflammatory state in the body. The gut microbiome composition and diversity are disrupted, creating an imbalance. Gut health issues like irritable bowel disorders, leaky gut, and hormonal issues can worsen in the body. Lack of sleep can also affect gut permeability and lead to nutritional absorption interference. Not only gut health, but poor sleep can also affect the metabolic pathways, immune state and neural pathways.

Gut microbiota

4. Research has shown that through the gut-brain axis, there is a bidirectional communication between the gut microbiota and the central nervous system. Beneficial bacteria like Lactobacillus and Bifidobacterium, which increase serotonin and gamma-aminobutyric acid production, help in the quality and lengthening of sleep. On the other hand, lack of sleep can lead to a reduction of beneficial bacterial flora, an imbalance in the microbiota, which includes probiotics, prebiotics, and postbiotics.

5. Studies have revealed that sleep, a natural physiological process, is important in maintaining a healthy gut microbiota and vice versa. Poor sleep patterns, insomnia, and sleep deprivation not only influence the emotional and cognitive well-being but also cause an imbalance in gut bacteria and gut flora. Therefore, there is a direct connection between sleep disorders and gut health, and resolving gut issues has a therapeutic effect.

6. The equilibrium of the sleep-wake cycle with the well-being of gut microbiota is very delicate and needs to be maintained by external factors. The balance can be easily disturbed by factors like stress, poor diet, lack of exercise, and poor sleep habits. Studies have shown that this reciprocal correlation shows sleep as the primary modulator between gut health issues and sleep length and quality.

7. Growing research has shown that the gut-brain axis plays a crucial role both directly and indirectly in the shift of composition of gut-microbiota with the development of sleep disorders like insomnia, sleep fragmentation, sleep deprivation and sleep apnea. Human studies have shown that 60-70% of the composition of gut microbiota depends on the oscillatory rhythm of the circadian rhythm.

8. Though Melatonin, a sleep hormone, is known to be produced by the pineal gland, it is actually the gut which is the primary source of it. This hormone is integral in modulating the sleep-wake cycle, immune-regulatory effect and antioxidant activity. The gut microbiota produces melatonin from tryptophan. This hormone has a favourable effect on microbial population and gut barrier functions. Therefore, any imbalance of gut microbiota directly influences melatonin production and disrupts the circadian rhythm.

9. Evidence from several studies has shown that a significant level of melatonin has been produced by bacteria in the intestinal flora, has a beneficial impact on intestinal barrier functions and a preventive effect in the human brain against neurodegenerative diseases like Multiple sclerosis, Alzheimer’s disease and Parkinson’s disease. Gut microbiota dysbiosis has been linked to the development of sleep disorders, autoimmune diseases, metabolic diseases like type 2 diabetes, pro inflammatory responses and neurological disorders.

10. Therefore, there is enough evidence to show that consequences in digestive health have a direct impact on the sleep-wake cycle and vice versa. Research has clearly shown that sleep deprivation can directly impact digestive disorders like gastric esophageal reflux, irritable bowel disorders and many gut health issues. Maintaining a consistent sleep schedule of 7-8 hours can help greatly in reducing the potential risk of many diseases as well as in maintaining a sound gut health. Not to forget that stress management is equally important for maintaining the equilibrium of gut health and sleep patterns. So, an early fiber rich dinner, less screen time, routine exercise, meditation and early sleep habits are essential components to maintain this balance.

Thanks for reading.

Peace and love 🙏

10 facts : What is SIBO or blind loop syndrome ?

by drjurisharma, posted in Aging,elderly, discomfort, disease, Blog, healing, health, SIBO, intestinal disease, IBS, diabetes, abdominal pain, bloating,gas, pain,, Supplement, Vitamin Deficiency, mental health,, wellness

1. SIBO, abbreviated as small intestinal bacterial overgrowth, is a condition where there is an overgrowth of bacteria that are not supposed to be present in the normal scenario in that part of the digestive tract. This occurs particularly following a disease or abdominal surgery, when the passage of food and waste becomes slower, creating a breeding ground for bacterial overgrowth.

2. When the wrong types of bacteria overgrow in the small intestine, they feed on the nutrients and food for the otherwise beneficial bacteria, which can lead to abnormal symptoms in gut health. These wrong types of bacteria can feed on the protein and vitamin B12, bile salts which are supposed to support the digestion of fats. In normal circumstances, the small intestinal bacteria digest the carbohydrate and convert it to short-chain fatty acids and gas. Therefore, when there is overgrowth of bacteria, more gas and toxins are produced in the gut leading to many GI symptoms and malnutrition in the long run.

3.The prevalence of SIBO is about 80-90% in cases of irritable bowel disorder, intestinal dysmotility , pancreatitis and chronic systemic conditions. It is more prevalent in the elderly and female population. Usually, the incidence increases with age and the presence of chronic intestinal disorders and dysmotility. SIBO is considered by clinicians as a differential diagnosis of other gastrointestinal non-specific disorders as the actual aetiology is still unknown.

4. The GI symptoms following SIBO are many:

• Gas, bloating, nausea

• Abdominal pain, distention

• Constipation

• Indigestion

• Weight loss, fatigue

• Watery or mucus in poop.

• Hard or lumpy poop.

5.Unexpected and systemic signs may appear due to excess toxins released in bloodstream

(endotoxemia) in SIBO:

• Food intolerence

• Fatty liver

• Fibromyalgia

• Irritable bowel syndrome

• Anxiety, depression, suicidal thoughts

• Endometriasis

• Disruption of mentrual cycle.

• Prostate diseases.

• Atrial fibrillation

• Siezure

6.Though the actual cause of SIBO is unknown, hence, there are several underlying conditions which can be the risk factors:

• Ageing: As age progresses, there may be changes in microflora, degeneration of acid-producing gastric cells, intestinal dysmotility which may lead to bacterial overgrowth.

• Irritable bowel syndrome leads to dysmotility, delayed transition of food, wastage.

• Chonic metabolic diseases like uncontrolled diabetes,

• Celiac disease,

• Lupus,

• Scleroderma,

• Pancreatitis,

• Chronic kidney diseases

• Fatty liver,

• Structural problems in the intestine due to gastric surgery, partial blockage, antibiotics or narcotic drugs overuse.

7. Several complications of SIBO can eventually worsen gut health if left untreated:

• Inadequate digestion and absorption of fat, protein, carbohydrate: Since, overgrowth of bacteria in the small intestine damages the bile salts so the fat remains undigested. The mucous lining of the intestines is damaged too by the excess bacteria causing poor absorption of carbohydrate, fat and protein. Therefore, there is malnutrition, diarrhoea, and weight loss.

• Vitamin B12 deficiency: As the fat remains undigested, the fat-soluble vitamins A, D, E, and K remain unabsorbed. Vitamin B12 which is synthesised in the small intestine is completely affected So, the individual may suffer from vitamin B12 deficiency. Therefore, due to B12 deficiency, nervous system functioning is affected, and blood cell production is lowered. There can be irreversible damage to the nervous system in the long run.

• Calcium absorption: Bacterial overgrowth damages the intestine slowly, resulting in poor absorption of calcium thereby affecting bone health. Weakened bones, prone to fractures, and osteoporosis are common. Kidney stones are also common in cases of poor calcium absorption.

8.There are no standard diagnostic tests for SIBO. The clinical symptoms of SIBO can be nonspecific. Usually, a carbohydrate breath test is considered which is inexpensive and non-invasive. A bacterial culture of jejunal aspirate of more than 1000 units/ml can support the diagnosis. Upper endoscopy is invasive but is done in patients to further support the diagnosis. Laboratory findings like vitamin levels, malnutrition markers are considered to support the diagnosis. Only, in rare cases is, biopsy of the small intestine done. Imaging tests like CT, MRI are done to rule out intestinal abnormalities.

9.Since the condition of SIBO is complex and can be involved with multiple underlying conditions, it is very difficult to manage and treat such cases. The treatment is mainly symptomatic like changing diet, lifestyle, and antibiotics to reduce the bacterial colonies. The recurrence of SIBO is also common so repeated courses of antibiotics are necessary. Supplementation of vitamins in certain cases is required. Surgery is only necessary in case of small intestinal abnormality, diverticula, bowel obstruction, or Crohn’s disease.

10.Again there is no standard diet for every individual who suffers from SIBO. It is individual-specific depending on symptoms and underlying conditions. The goal of diet change is to assist in the treatment and lower the symptoms. The diet should be low in carbohydrates, low in fat, and moderate to low in fibre. Processed sugar items, dairy, whole grains, deep-fried items, and raw vegetables should be avoided. Generally, probiotic-rich food, meat or fish, rice, cooked vegetables, plenty of fluid/water/soups and vitamin supplementation are recommended by the experts.

Thanks for reading.

Peace and love 🙏

10 facts: Is hydrogen water a hoax or is it real?

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, healing, health, Heart friendly, weight friendly, gut healthy, constipation,, Hydrogen, hydrogen water, hydrogenated water, Inflammation, diseases, environmental damage, health issues, Science, wellness

1.Hydrogen water, also known as hydrogenated water, is simply regular water infused with hydrogen gas. The regular water is H2O with extra H2 gas added, which is what makes hydrogenated water. This hydrogen-rich water has become quite popular nowadays as it has been found to have health benefits. Manufacturers are now selling hydrogen water bottles across the globe for it’s health benefits. Extensive research has not been done so far, regarding the use of hydrogen water. Yet, it has been very popular in some countries, such as Japan.

2. As far as nutritional benefits are concerned, hydrogen water is the same as regular water in terms of calories, protein, fat, and carbohydrate which is nil. However, some manufacturers and providers do add trace amounts of vitamins A and C, magnesium, potassium and sodium sulfate to enhance the nutritional benefits. As already mentioned, not much research has been done in this context, but some experts do believe that drinking hydrogen water is beneficial for health.

3. Anti-inflammatory: Hydrogen water does contain anti-oxidants. Anti-oxidants fight inflammation and reduce oxidative stress. Every day, our body is inflicted with various types of physical and mental stress, which comes from external forces like pollution, sun exposure, toxins from the environment, food, day-to-day mental stress of various nature, also from normal body functioning, all these factors are sources of inflammation, diseases and cancers. Therefore, molecular hydrogen can help to some extent to combat oxidative stress and reduce inflammation.

4. Endurance and Mental health: Several studies have shown some positive results of increasing endurance and lowering fatiguability after drinking hydrogen water. It does show performance improvement, increasing energy, and endurance in the case of athletes, though scientifically, still not verified. It has been found to lower physical stress and reduce recovery time after heavy workouts.

Some studies on mental health have shown that drinking hydrogen water daily for 4 weeks showed marked improvement in mood disorders, panic disorders and anxiety.

5. COVID-19: More research is still needed to establish the fact, that hydrogen water consumption did slow down the immune response which is known as a “cytokine storm”. The use of hydrogen water was useful to reduce the cytokine response of Covid 19 virus which otherwise could lead to organ failure. But, as already mentioned, more studies are required to clarify that hydrogen water can potentially treat Covid 19.

6. Liver and kidney functions: Studies of cases of non-alcoholic liver diseases, cases of hepatitis –B virus, drinking hydrogen water has shown positive results in lowering fat storage in the liver, aiding the treatment process and improving the liver function. But then, research is limited in such cases too. A study on dialysis patients has shown, that intake of hydrogen-rich water caused improvement in renal function and BUN (blood urea nitrogen).

7. Cancer treatment: Hydrogen water does show positive results in aiding cancer treatment. Since hydrogen water contains anti-oxidants, and acts as an anti-inflammatory, an immune booster does give promising results during cancer treatment by improving both physical and oxidative stress. A study regarding colo-rectal cancer showed anti-cancer properties.

8. Metabolic syndrome: Metabolic syndrome is a condition which includes high blood pressure, high cholesterol, high triglycerides, obesity or excess belly fat. The risk factors of metabolic syndrome are oxidative stress and chronic inflammation. Some studies have shown that intake of hydrogen water around 1 litre daily, in individuals on a 10-week study marked a significant reduction of risk factors of metabolic syndrome and showed a favourable effect on the metabolic processes in the brain and even ageing.

9. Negative effects: As far as health experts are concerned, there are no known side effects of drinking hydrogen water. Research is still not enough to establish even the health benefits thathave been claimed so far. More studies are required to verify the health benefits. In the case of individuals with high-intensity workouts, athletes, and chronic kidney diseases, there can be a risk of hyponatremia in drinking excess hydrogen water.

10. Though several studies do show potential health benefits of drinking hydrogen water over regular water, but still, continuous trials and more studies are still required to establish the benefits. Many manufacturers are selling hydrogen water bottles which are quite expensive. Again, depending on the source of water, the authenticity of brands is important to avail the actual health benefits claimed. The bottom line is that there is still not 100% proof of the potential health benefits. If affordability is there, there is no harm in using hydrogen water for drinking, otherwise, regular drinking water is great as well.

Thanks for reading.

Peace and love 🙏

Dealing with emotional thoughts: A perspective 🙌

by drjurisharma, posted in Anger, frustration, pain, jealousy, hatred, fear, greed, lust,, Emotional thinking, thoughts, feelings,fears, pain, anxiety, hurting, Emotional thoughts, fear, pain, emotions, healing, health, life, Mind, thinking,overthinking,wondering mind, Science, self healing, wellness

Emotions are subjective yet universal among all humans. They significantly influence our daily lives, decision-making, behavior, relationships, psychological states, and physical health.

Our emotional thoughts arise from emotional reasoning in response to situations, people around us, events, and past experiences. Emotional responses trigger our thoughts, feelings, actions and behaviors in reaction to external events, situations, or circumstances. Thus, emotions play a crucial role in our everyday lives and the decisions, we make.

Research states that all things in the Universe are made of energy which has a vibrational frequency. Emotions too, have amplitude and frequencies. Positive emotions like peace, love, and joy are found to have higher frequencies as compared to negative emotions like anger, fear, guilt, and sadness. According to the frequency chart, emotions like guilt, and shame have as low a frequency of 30-20 Hz to emotions like love, peace have as high as 500-600 Hz. Studies often link low frequency to disease state, depression and stress. Negative thoughts and feelings can often create a low vibrational frequency state which can create anxiety, and stress and affect our physical health.

Studies have consistently shown that negative emotional thoughts and feelings can significantly affect our physical health and overall well-being. The importance of the mind-body connection and the gut-brain connection highlights how our physical body responds to our thoughts, feelings, and mental state.

While unwanted changes, negative experiences, and challenging situations are a part of life, learning to manage our emotional state and well-being is a significant challenge—but it is certainly not impossible. Events such as:

Death of a loved one

Suffering from an illness

Getting laid off from a job

Divorced

Getting married, having a baby

Financial issues

Dealing with a pandemic or war-like situations

Cheating partners

Domestic violence

Physical health often suffers when emotional health is struggling. During times of emotional crisis, many individuals may seek an escape through unhealthy coping mechanisms such as alcohol abuse, drug abuse, or binge eating, attempting to suppress their emotional turmoil. Unfortunately, this approach does not lead to healing and can result in disastrous consequences. The list of physical impacts and symptoms experienced in a state of emotional stress is extensive.

Physical symtoms frequently seen as:

Palpitation

Chest pain

Back pain, neck stiffness

Fatigue , tiredness

Poor sleep, insomnia

High blood pressure

weight loss / obesity

Stomach upset like bloating, acidity

Physical signs of our mental state can often be quite apparent. Additionally, there are mental symptoms that we or those around us may observe, even if we attempt to deny them. Here are several such signs:

*Resisting to acknowledge the thoughts instead of accepting

*Not self-realising and accepting the present situation

*Trying to control the situation or the people around

*Suppressing emotional thoughts and feelings instead of expressing

*Living in blame

*Focussing on lacks

*Forgetting gratitude

Dealing with emotional thoughts is not easy. It’s important to remember that while I cannot control external events or situations, I can influence my own mental state to cope and adapt positively. Here are five simple tools that can help bring about a positive shift in the mental state:

1.Self-Responsibility: Recognizing and taking responsibility for our mental state is crucial. Often, we create more pain and hurt from emotional thoughts and feelings by overthinking and getting caught in repetitive loops, rather than addressing the actual situation. It’s important to remember that 95 to 98 percent of our worries are self-created rather than based on reality. Only about 2 to 3 percent of our concerns are truly justified. Therefore, it’s essential to become aware of and take responsibility for our mental state, as this is the first step towards creating positive change.

2. Let go of control: We have to understand that we cannot control everything that happens in our lives. We have to let go and trust the Divine and timings of life. Letting go is important to heal and restore balance.

3.Journaling and practicing gratitude: Daily journaling can release deep thoughts that might otherwise feel heavy and hurtful. Practicing gratitude and maintaining a thankful mindset can elevate our vibrational frequency and promote healing.

4. Healing the Sacral Plexus Chakra: According to Yogic science, the sacral chakra is responsible for maintaining emotional balance, creativity, and a sense of vitality. To heal this chakra, engaging in yoga and physical activities such as dancing, swimming, and savoring life’s simple pleasures— like playing with a child, listening to birds chirping, or enjoying the sound of flowing water—can help release blockages.

5. Daily Affirmations: Choosing words and phrases that align with your life goals, such as mantras or sacred verses, can significantly enhance your positivity and resilience. Reciting these affirmations each morning can set a positive tone for the day. Some powerful examples include: “I trust the Universe,” “I am strong and powerful,” and “I let go” “My food nourishes my body and mind”.

Every day, we experience a wide range of emotions based on external events, past memories, current situations, and various circumstances. It is essential for us to recognize our emotional limitations and boundaries in order to protect our mental well-being. One of the most important things we can do is to let go and trust the Supreme, the Divine, as not everything is within our control.

Self-reflection is crucial for restoring our emotional balance. Engaging in daily activities such as meditation, yoga, chanting, and appreciating the small joys in life holds great significance in achieving mental equilibrium. Finally, staying grateful and expressing our thankfulness for this journey of life is truly fulfilling.

Thanks for reading.

Peace and love 🙏

10 facts: Are Psyllium husks gut-friendly?

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, Cholesterol, Food, Fresh, local, produce, healing, health, Heart disease, Heart friendly, weight friendly, gut healthy, constipation,, Heart, cardiovascular disease, cardiomyopathy, Psyllium husks, baker’s, seeds,, Psyllium husks, functional foods, stomach, abdomen, intestines, Supplement, wellness

1. Psyllium husk is derived from seeds of the plant genus Plantago ovata. It is rich in water-soluble and unfermentable dietary fibres. It is used in food and nutraceutical industries. It has become popular due to its various health benefits. Psyllium is used as a fibre supplement because of its mucilage content. The mucilage is obtained by grinding the seeds of the Plantago group. These plantago seeds are often referred to as psyllium husks.

Gut- friendly

2. Psyllium husk has been used as a food thickener, fibre supplement, binding agent, gelling agent, and so on. Research studies have shown that it is rich in soluble fibres. So, it has been used as a laxative, which eases bowel movements, making it gut-friendly. Studies have shown that since it eases constipation, it helps to prevent complications like bloating, gas, haemorrhoids, and anal fissures.

Heart friendly

3. Some research shows that it benefits heart health too. Adding psyllium to a daily diet can lower the level of LDL ( bad cholesterol) and can help to maintain cholesterol levels. As we know high cholesterol can lead to conditions like chronic heart diseases, hypertension, diabetes, stroke and heart attack. So, adding psyllium in diet can help to prevent such conditions by maintaning the blood cholesterol levels.

4. Since psyllium is rich in fibres, adding them to a daily diet can even help to maintain the glycemic balance. Therefore, having a diet rich in fibre can be an important step in maintaining the balance of insulin and blood sugar. Psyllium can be a healthy prebiotic too, which can help to produce healthy bacteria and probiotics in the gut.

Weight management

5. A 2023 review study has shown that adding a moderate amount of psyllium fibers to the diet can help reduce weight in people who are overweight and obese. Managing weight can help to reduce the risk of chronic conditions like heart diseases, high blood pressure, gallstones, and breathing issues. Therefore, using of psyllium husk can be used for weight management but, off course under guidance of trained dietary experts.

Constipation

6. Studies have been carried out with the use of psyllium husk in the treatment of irritable bowel syndrome (IBS). The symptoms of gas, bloating, and constipation of IBS have been reduced or the frequency of symptoms can be minimized by the use of psyllium in the daily diet of such patients. This significant change has been reviewed in various research on IBS treatment. Hence, the use of psyllium is found to be suitable in the treatment of IBS.

7. Psyllium is also referred as ispaghula for its mucilaginous compound. It has been used in a variety of herbal medicine to treat various ailments in Asian countries like India and China. It is used to treat skin irritations, bladder problems, wound healing, high blood pressure and digestive problems. Studies do show that psyllium has gelatinous properties, and natural polymers for wound healing and scar reduction.

8. Regarding its uses in various functional food products, for its tremendous health benefits. It has many metabolic effects, lipid-decreasing effects, anti-diabetic, anti-hypertensive, delayed gastric emptying and lower glycemic index. Clinical studies have shown that it decreases the rate of glucose absorption, lowers the post-prandial insulin, and lowers LDL cholesterol by reducing bowel absorption. For its rich source of dietary fibre, it eases bowel movements and relieves constipation.

9. Psyllium is an important source of water-soluble fibre, hydrocolloid in nature due to its solubility and viscosity. The gum extracted from psyllium husk is used in various food items like gluten free bread, pasta, pizza, cookies, ice-creams, jams and myonnaise. It is used as a gluten replacement and also added with the various nutritional benefits to the food products. Due to its prebiotic benefits, it has been very popular as a gut-friendly ingredient in food items.

Bakery items

10. Commercially, psyllium is available as in powder or particle form derived from the seeds of the Plantago plants. It is conventionally used as a laxative agent, and as dietary fibre supplements, in various functional food products, nutraceutical industries, and food industries in breakfast cereals, bakery products, desserts and snacks. Psyllium has no known serious side effects except sometimes may have allergic reactions. The dosage of psyllium is around 5-10 gm with a meal or with water as a supplement. The dosage can be increased gradually if it is tolerable. As I always mention, it is important to follow instructions from experts or Physicians while using.

Thanks for reading.

Peace and love 🙏

10 facts to know about Vitamin D linking to mental health🧠

by drjurisharma, posted in cognitive health, fear, pain, emotions, Food, healing, health, life, mental health, Vitamin Deficiency, mental health,, wellness

Vitamin D deficiency is critical for both physical and mental health. Here are some facts to understand the impact of vitamin D on mental health.

1.Several research studies have concluded that low vitamin D levels are directly linked to anxiety, mood changes, depression and cognitive dysfunction such as impaired memory, sadness, weight loss and loss of appetite. Studies have not shown that vitamin D deficiency causes depression but people who suffer from depression do show low levels of vitamin D.

2. Vitamin D mainly maintains the body’s calcium homeostasis. It is also crucial as a neurosteroid hormone and plays a significant role in maintaining normal brain functions and helping in brain development. Therefore, numerous studies have shown that hypovitaminosis D is linked to depression and neurocognitive disorders.

3.Some studies have shown that seasonal affective disorder (SAD) is more prevalent in winter as there is a lowering of Vitamin D levels in the cold season. Lack of exposure to sunlight in winter months is shown to increase the incidences of depression, mood changes and anxiety issues.

4. Rising cases of suicide have been a common risk factor for low vitamin D levels (psychiatric times.com).A research study in 2023 found a correlation between low vitamin D levels with cases of suicidal behaviour. Therefore, vitamin D supplementation is mandatory for all those who have low levels can help to address mental health issues and prevent cases of suicide thereby saving lives.

5.As mentioned earlier, Vitamin D is required for normal brain development. Vitamin D supplementation is essential in childhood for overall brain and cognitive development. Low levels of vitamin D have been found in many cases of ADHD (attention deficit hyperactive disorder). Improved levels of vitamin D by supplementation have shown marked improvement in symptoms of ADHD children.

6. Vitamin D deficiency has been found to have a direct correlation with adult schizophrenia. Studies show that it is quite common to have in individuals with poor nutrition, elderly persons, people living in regions with insufficient sunlight, or during pregnancy. So, it is important to routinely check the levels of Vitamin D to reduce such risk factors. Correction of the levels of vitamin D shows marked improvements in symptoms of such mental illness.

7. Vitamin D acts as a neuroprotective neurotransmitter and helps to maintain the functions of neurons and glial cells of the central nervous system. So, administrating Vitamin D helps to reduce the oxidative stress and neurotoxicity on the cortical neurons. Therefore, controlling the neuronal inflammations helps to reduce many psychiatric illnesses.

8.Strong evidence shows that low levels of Vitamin D are related to neurodegenerative diseases like Alzheimer’s disease, dementia, and Parkinson’s disease. Vitamin D supplementation can improve or even prevent the neurodegenerative process by reducing the deposition of beta-amyloid plaques, intra-neuronal tangles of tau-protein and loss of cholinergic neurons and synapses.

9. Vitamin D levels ranging from 50nmol/L or above are sufficient to maintain overall physical and mental health well-being. Blood levels below 20 ng/mL are treated as insufficient and require immediate vitamin D administration. Normal levels can be maintained by exposure to sunlight, vitamin D supplementation and food sources like oily fishes, eggs, meat, liver, veggies like broccoli, pumpkin, green leafy veggies, green peas, avocados and many more.

10. Though vitamin D is not the only cause of mental health issues, essentially, it is an important nutrient to maintain normal brain function and neurochemistry. In the general population, many people do suffer from vitamin D deficiency, unknowingly. Supplementation of vitamin D can improve the blood levels in individuals and can at least help address the challenges of mental health issues.

Thanks for reading.

Peace and love 🙏

8 facts: Are CoQ10 supplements actually necessary ? 🙌

by drjurisharma, posted in antioxidant, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, butter,dairy,inflammatory,disease,cancer,gut health,, cognitive health, Flavonoids, antioxidants, anti inflammatory, healing, health, Heart disease, life, meditation, inflammation, disease, physical health, mental health, wellbeing, Parkinson disease, migraine, fertility, Science, Supplement, Coenzyme, Q10, wellness
CoQ10 supplement

1.We have often encountered a supplement named CoQ10, commonly seen in the drug aisle of a supermarket. Let’s know, what exactly CoQ10 is. Well, it is Coenzyme Q10, a fat-soluble, vitamin-like molecule, which is naturally present in every human cell. It is a powerful antioxidant that converts food into energy. Like all other antioxidants, it can neutralize the free radicals and prevent oxidative stress. Therefore, it can prevent us from many chronic health problems and slow down the ageing process.


2.Clinical studies have suggested that CoQ10 plays a significant role in:
It may help in preventing heart-related problems.
Improving the overall immunity.
Improve physical endurance.
Improves male fertility.
Prevent migraine.
Improves blood sugar level in diabetes.
Supports treatment of neuro-degenerative disease like Parkinson’s disease.


3.Evidence-based studies show that people who have a history of heart failure show reduced incidence of heart attack when they take CoQ10 supplements daily along with conventional medications. But then, it has to be prescribed or taken under expert guidance. Several studies have shown similar preventive or improvement levels in cases of heart issues like high cholesterol, high blood pressure, congestive heart diseases and heart damage caused by chemotherapy.


4.CoQ10 supplements have no approval from the FDA or other Drug Regulatory Authorities for the treatment of any medical conditions. However, yet it is easily accessible and available as the over the counter supplements and has been quite popular. It is often recommended as a dietary supplement by many Physicians and Specialists as a supportive therapy to conventional
treatments.

Food sources

5.Naturally dietary sources of CoQ10 intake are enough for overall well-being. Dietary sources are wide variety of whole grains and oily fishes. CoQ10 supplements are not necessary for a healthy individual who has a balanced diet. Supplements of CoQ10 is only necessary for those who suffer from CoQ10 deffeciency, or have health issues like heart disease, migraine, neuro-degenerative
disease or other chronic health conditions. It is not advisable to pick a supplement bottle from the supermarket aisle and start popping unless clinically recommended.

Nuts and seeds

6.As already mentioned, the human body makes enough of CoQ10 as much as it needs. The body content is about 500 to 1500mg and it declines with ageing. The food sources are organ meats, fatty fishes like salmon, sardines, trout, mackerel. As for vegetarians, soya products like tofu, soy milk, and soy yogurt are good food sources. Nuts and seeds, lots of vegetables including broccoli are rich sources of CoQ10.


7.Though CoQ10 supplements do not have major risk or side effects, it is still not advisable to take unless necessary for specific health issues. Some side effects of supplementation can be diarrhea, nausea, heartburn. It may interact with medications like blood thinners with further lowering of blood pressure, or in case of diabetes, subsequent lowering of blood sugar along with hypoglycemic drugs.


8.Due to certain chronic health issues like heart problems, migraine, fertility issues or
neurogenerative conditions, Physicians do recommend CoQ10 supplements. There is no standard dose as such. Depending on the individual’s requirement, dosage varies from 60-500 mg daily. The highest dose recommended daily is about 1200 mg. As it is a fat-soluble substance, it is best absorbed with a fatty meal and better if taken at night.

Thanks for reading.

Peace and love 🙏

10 compelling reasons to consume Flavanoids to combat oxidative stress 🙌

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, detoxification, vegetable,, emotional health, Flavonoids, antioxidants, anti inflammatory, Food, Fresh, local, produce, Fruits, veggies, berries, healing, health, life, meditation, inflammation, disease, physical health, mental health, wellbeing, nature, self healing, wellness
  1. Flavonoids are naturally occurring polyphenolic compounds in various deep-coloured fruits and vegetables. There are 6 different varieties of flavonoids, all of which have antioxidant properties and can help the human body to get rid of different toxins and stress. Therefore, including flavonoids in your routine diet can help to get rid of many chronic health conditions.
  2. Dietary Flavonoids are of 6 subtypes :
    Flavanols , Flavones, Flavan-3-ols, Flavanones, Isoflavones, Anthocyanins.
    Coloured fruits, vegetables, and plants are all rich in flavonoids. Naturally, they are found in apples,purple and red grapes, berries, peaches, oranges, cocoa, chocolate, green tea, black tea, chamomile tea, vegetables like broccoli, lettuce, tomatoes, scallions, red peppers and onions. Flavonoids are dark-coloured pigments so they act as natural pesticides and protect the plants from harmful UV rays, bacteria, viruses and harmful insects.

3. Main functions of flavonoids:
•Powerful antioxidants
•Fights inflammation
•Free radical damage and prevent oxidative stress.

•Anti-haemorrhagic and vasodilatory effects.
•Certain flavonoids, due to their anti-inflammatory and antioxidant properties prevent cancer cells from multiplying and decrease the risk of some cancers.

4.Research shows that oxidative stress can lead to cellular damage and disease development. So, oxidative stress can cause many disease conditions like cancers, diabetes, cardiovascular diseases like hypertension, atherosclerosis, chronic inflammatory diseases, and neurodegenerative diseases. Flavonoids play an important role in reducing this oxidative stress and free radical damage, thereby preventing cellular damage.

Cocoa (Dark Chocolate)

5.Numerous studies have shown that cancers develop due to oxidative stress, genetic mutations,hypoxia and reduced apoptotic function. Apoptosis, in simple terms, is a normal cellular activity whereby the body tries to eliminate unwanted cells. Flavonoids play an integral part in promoting apoptotic cellular pathways and preventing cancer cells from proliferating and multiplying.

6.Research shows that flavonoids protect the different organs including the liver and brain from free radical damage. Studies show that flavonoids have protective effects of various liver injuries caused by drug and alcohol usage. Since, they are anti-inflammatory, and antitumor, they protect the hepatocytes from inflammation and fibrosis.

7.Flavonoids are a polyphenol group of compounds that can improve and reduce the symptoms of depression and anxiety. Clinical studies in the past have shown that dietary intake of flavonoids can lower the risk of depression. However, further studies are still anticipated to make substantial proof.

8.Flavonoids are best when naturally consumed as all dark-coloured fruits, vegetables, and green tea contain abundant polyphenolic compounds. It should be included in the routine diet for overall
well-being. However, many flavonoid supplements are out in the market. The best supplements are Cucurmin (Tumeric), Green tea, grape seed extract, Resveratrol, Quercetin, hesperidin and Rutin.

9. Toxicity: Intake of natural flavonoids on a daily diet is usually enough. Sometimes, flavonoids supplements are clinically recommended. However, the risk of flavanoid toxicity exists, if someone takes a huge amount of highly potent supplements. It may affect anaemic and elderly patients as flavonoids may bind with non-heme iron. Flavanoid toxicity may cause liver failure, hemolytic anaemia and male reproductive issues. Recommended daily dose of consumption should be around 400-600mg/day.

10.A healthy routine diet rich in flavonoids will provide all the necessary support to the human body to maintain biological activity, provide anti-oxidant effects, reduce oxidative stress and prevent chronic diseases, maintain cardiovascular health and prevent infectious diseases. The key point is that the food readily available to us contains the most effective flavonoids and antioxidants that fortify our health and immune system, making expensive supplements unnecessary

Thanks for reading.

Peace and love 🙏

8 facts: Giloy, an understated herb 🪴

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Food, healing, health, herb, Plant, medicinal, Ayurvedic, herbal remedies,, Science, skin, cancer, anti inflammatory, plant, nature, medicine, herb, stomach, abdomen, intestines, wellness

Hello everyone 🙌

  1. Giloy is a herbaceous plant, a climbing shrub, where every part of the plant including the stems has various medicinal benefits. It is mainly grown in the Indian subcontinent, many Asian countries including China, Thailand, Philippines, Myanmar, tropical regions of Australia, and North and South Africa. It prefers a warm tropical climate to grow. Despite its holistic health benefits, it is still not known to many. Scientifically, it is called Tinospora cordifolia.
  2. Giloy is considered an essential herb in Ayurvedic medicine. For centuries, people have been using this herb to treat a long list of health ailments, including infections, fever, asthma, diabetes, gout, diarrhoea, jaundice, urinary problems, and skin conditions.

3.Research studies have found that giloy has many potential compounds like alkaloids, terpenoids, lignans, and steroids which have therapeutic benefits. Studies have also found that the herb contains anti-inflammatory and antioxidant properties which can fight oxidative stress and prevent microbial growth of viruses, bacteria and fungi.

4.Studies show that the entire herbaceous plant including roots, stems, and leaves have medicinal properties. The stems of the plants, especially are potent anti-stress, antioxidant, anti-diabetic, anti-arthritic, anti-allergic, anti-inflammatory, immunomodulatory and anti-cancer properties. Giloy also aids in digestion and gut health.

5.Some studies have shown that the alkaloids found in giloy called berberine work like the medicine metformin and help to reduce blood sugar. It can be effective in controlling blood pressure and reducing the level of LDL( bad cholesterol), hence lowering the risk of heart disease.

6.Lab studies have shown that Giloy can be effective in treating seasonal allergies, and skin conditions like scabies and hay fever. It is effective in controlling asthma. Studies show that it can strengthen the immune system and fight against many pathogens like Klebsiella pneumonia, Pseudomonas, Ecoli and many more.


7.Though Giloy doesn’t have harmful side effects, it is important to use it under expert guidance. The herb can interfere with medications like diabetic medicines, anti-hypertensives, and autoimmune medications. It should be avoided during pregnancy and breastfeeding. Commercially, it is available in capsule form, powder form and tincture. The dosage can be different in different forms depending upon the manufacturer’s preparation. So, it is important to read the label and dosage before buying and using the product.


8.Depending upon the recommended dose on the label of the package and under expert guidance, giloy can be consumed safely with the best outcome. However, in the case of auto-immune diseases like Crohn’s disease, and lupus, the immune system can be overstimulated. Side effects like hypoglycaemia, dizziness or stomach irritation might appear in some individuals. The recommended dosage is about 2-6 gm in the case of adults and less than 500mg in the case of children in either powder or capsule form. Giloy juice can be taken in 2-3 teaspoonfuls with water on an empty stomach in the morning.

Thanks for reading.

Peace and love 🙏