Category: brain

10 facts: All about rooibos tea ☕️

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, Blood sugar levels, diabetes, exercise insulin levels, insulin sensitivity, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, Brain, nervous system, gastrointestinal disease, autism, cancer, cognitive health, Cortisol, stressful, stress, sleep, sleep deprivation, anxiety, depression, wakefulness, hormones, melatonin, emotional health, hair, healing, health, Heart disease, life, Nature,, Obesity, weight loss, Rooibos, herbal tea, green tea, antioxidants, caffeine free, tannin, anti inflammatory, mineral supplements, bone health, skin health, sleep, weight loss, exercise, wellness, Science, self healing, Skin, hair, wellness

1. Rooibos, a caffeine-free, colourful tea produced from Aspalathus lineriaris, originated in South Africa and has been used for centuries in both fermented and unfermented forms. In recent times, this tea has attracted ample research studies for its nutritive profile of phenylphenols, flavones, flavonoid and several minerals. Because of its rich nutrients, this tea is known for its immune-boosting properties and has potent anti-inflammatory and antioxidant effects. It has plenty of phytochemical, which can prove to be very beneficial for humans and prevent chronic and lifestyle diseases. Therefore, this tea has been very popular worldwide.

2. Rooibos is a caffeine-free herbal infusion tea that contains very low levels of tannins. Thanks to its flavonoids and phenolic acids, which have antioxidant properties, rooibos tea helps prevent the formation of reactive oxygen species (ROS). By neutralizing and reducing ROS, rooibos can potentially help prevent chronic and lifestyle diseases, such as diabetes and cardiovascular conditions. Additionally, rooibos is effective in converting harmful ROS into less damaging hydroxyl radicals. Due to these findings from animal studies, rooibos has become a popular herbal tea and dietary supplement.

3. Rooibos tea is native to South Africa, grown originally in the mountains of Cederberg. But due to its popularity, it has been successfully grown worldwide. It is made from the bush of Aspalathus lineriasis. The loose leaves of the plant have the strongest flavour and the highest health benefits.

Though there are different varieties of rooibos, as already mentioned, loose leaves are most popular. Its taste is a little similar to green tea, with a strong nutty and sweet flavour and a pleasant aroma. Since studies have shown its amazing health benefits, and being caffeine -free, it can be taken 3-4 times daily, both day and night for overall wellness.

4. It has a potent list of amazing health benefits, namely :

• It has potent antioxidant properties which prevent oxidative stress and reduce cell-damaging radicals.

• Heart-friendly, as it can lower blood pressure by blocking ACE (angiotensin-converting enzyme). It also reduces cholesterol levels.

• It balances blood sugar levels and improves insulin sensitivity.

• It aids metabolism, and its anti-inflammatory effects help in reducing stomach cramps and bloating.

• It reduces skin irritation, prevent acne as rooibos contain Alpha -hydroxy acid and Zinc.

• Rooibos helps in strengthening bones as it is packed with minerals.

• It is a sleep aid due to its relaxing and soothing effects.

• It aids in weight loss.

5. Digestive health: Rooibos is rich in flavonoids, phenolic acids and minerals, because of which it strongly supports gut health. It has a calming and gentle effect on the stomach. Among the many benefits for digestion, the important effects are :

• Relieves cramps and stomach pain due to its natural anti-spasmodic effect; it acts as a relaxant to stomach muscles.

• It strengthens the gut intestinal barrier and prevents leaky gut disorder. It helps in maintaining the intestinal lining. This effect is prominent with unfermented rooibos.

• Due to its anti-inflammatory effect, it reduces gut inflammation and lowers oxidative stress.

• It is soothing to the stomach and prevents acid reflux and iron absorption blockage due to its low tannin content.

6. Skin health: Rooibos has been consumed as a herbal infusion for centuries in both fermented and raw form. Because of research studies, in recent years, it has become very popular globally.

Due to its rich nutrients of polyphenols and minerals, it is considered an important ingredient in many herbal skin care products. It is considered as a valuable component in skin care for being anti-inflammatory, antioxidant, soothing, hydrating, moisture retention, hence used in many skin care products. Some of the amazing benefits to skin health are:

• Fights ageing and reduces wrinkles as it combats oxidative stress.

• Soothing to sensitive skin as it has a calming effect and prevents irritation.

• Prevents acne, reduces pores and gives clear skin.

• Protects the skin barrier, improves hydration, and helps reduce skin dryness• Reduces hyperpigmentation, promotes skin elasticity, giving firmer skin and a youthful appearance.

• Protects the skin from pollution and environmental damage.

7. Side effects: Overconsumption of any beneficial compound can lead to side effects too. Drinking rooibos tea in moderation is safe and has no severe side effects. But long-term heavy drinking of rooibos can lead to some side effects:

•Raised liver enzymes and liver toxicity in long-term use of high amounts of rooibos.

•Due to the presence of phytoestrogen which can mimic the natural oestrogen in the body can be an issue in case of hormone sensitive individual, women with breast cancer.

•Interact with medications like blood pressure medicine and cholesterol-lowering medication (statins). Due to its oxalate content, it can be problematic for kidney patients.

8. Dosage: Due to its tremendous benefits for balancing blood sugar, sleep, skin, hair, and immune-boosting properties, many people like to drink rooibos tea infusion. It is completely safe to drink every day, provided the daily intake is 2-4 cups or within 400-1200 ml/day. Overconsumption doesn’t really help in providing the benefits. Instead daily moderate intake slowly can uncover its amazing benefits to overall wellness. Studies show that a maximum limit of 4-6 cups can be tolerated as a healthy adult. Rooibos herbal infusion without sugar is healthy but adding sugar, heavy cream can increase the calorie content. It is suitable even for children and pregnant women too, in moderation.

9. Rooibos v/s other teas : Green tea, black tea contain caffeine while rooibos is caffeine free so can be taken anytime including night time. Other teas when brewed a little longer gives a bitter taste due tannin but rooibos has very low tannin and has sweet nutty taste and great aroma. Red rooibos is fermented, intense in flavour and colourful, while green rooibos is unfermented, looks similar to green tea and has high antioxidant levels.

10. Takeaway: There is no doubt that rooibos is a very beneficial herbal tea, known for its nutritional profile. It does promote overall wellness, backed by science-based studies. In recent times, it has become very popular worldwide, and not just in its origin, South Africa, but several other countries have started growing it due to its increasing demand. It can be taken every day due to its anti-inflammatory, antioxidant properties and rich mineral profile for overall health and well-being. Plain rooibos tea is zero-calorie and is the healthiest version, without sugar, additives or whipped cream.

Thanks for reading.

Peace and love 🙏

10 facts: The link between obesity and brain function🧠

by drjurisharma, posted in Adult over 50, Adults, young people,, Aging,elderly, discomfort, disease, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, emotional health, Food, Food, eating habits, eating disorders, eating preferences, choices, culture, traditions, travels, family, Fresh, local, produce, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, Heart disease, Infection,inflammation, Obesity, brain fog, brain function, fatigue, depression, anxiety, diabetes, disease, neurological disorders, memory, metabolic disorders, Science, self healing, wellness

1.Research has already stated that obesity is a risk factor for neurocognitive decline. Obesity has become a widespread lifestyle disease that affects individuals regardless of age, gender, race, or culture. Many studies are being conducted on the relationship between obesity, defined as an excessive accumulation of fat, and brain function. Research has shown that structural changes in the brain are quite common among elderly obese individuals, particularly in the form of cerebral atrophy in grey matter and alterations in white matter volume. Notably, there is a reduction in the volume of the frontal lobe, hippocampus, thalamus, and anterior cingulate gyrus. Changes in brain structure can also occur in younger obese individuals.

2.BDNF (Brain-Derived Neurotrophic Factor): Adverse effects of Brain-Derived Neurotrophic Factor (BDNF) have been linked to lifestyle and diet choices. Low levels of BDNF, which affect neuronal plasticity, are associated with obesity and diets high in sugar or fat. Studies have shown that a high-fat diet, which leads to increased body weight, is related to reduced BDNF levels in the prefrontal cortex. This reduction can result in learning difficulties and impaired food intake control. Additionally, elevated serum leptin levels in obese individuals can lead to changes in the structure of the hippocampus and negatively impact memory performance.

3.Inflammation: When there in increased accumulation of fat tissues, they trigger chronic inflammatory responses, chemicals (cytokines) which crosses the blood brain barrier and reaches the brain cells, thus neuro-inflammation starts. The inflammation process spreads in the brain, damaging the cells, mitochondrial malfunctions which causes oxidative stress, brain immune cells (microglia) becomes hyperactive causing inflammation which can be localised or extensive. The hypothalamus, which controls appetite, is affected, creating a vicious cycle of weight gain. The hippocampus and Amygdala are affected, which causes issues in memory and emotion control.

4. Brain metabolism: Obesity can greatly affect brain metabolism by disturbing core functions such as :

• Obesity can disturb the brain’s insulin sensitivity, which in turn disrupts appetite control and impairs neuronal energy production.

• Mitochondrial dysfunction and low energy production in brain cells can increase oxidative stress and the release of harmful toxins, leading to cellular damage.

• Neuro-inflammation spreads due to the release of inflammatory chemicals like cytokines from visceral fat, leading to an increased risk of cognitive decline, dementia, depression, anxiety and diseases like Alzheimer’s disease.

5. Obesity and insulin resistance: In a healthy individual, insulin acts as an appetite-suppressing hormone on the brain. Studies show that obesity plays a key role in disrupting insulin sensitivity, causing impaired appetite control, resulting in metabolic disorders like type 2 diabetes. Studies have already linked obesity to diseases like heart attacks and cancers. Apart from appetite regulation, insulin in the brain helps in the co-ordination of fat distribution by promoting healthy subcutaneous fat storage instead of unhealthy visceral fat storage. Obesity leads to brain insulin resistance, causing an increase in visceral fat, increased food cravings, overeating, anxiety, depression and further weight gain.

6. Behaviour changes: Dealing with obesity is a gradual process which requires lifestyle changes, dietary changes, physical activity, counselling and a constant support system. Some of the key pillars are :

• Reduction of calories on a daily basis by 500 to 1000 calories. Switching to a calorie deficit diet like whole grains, vegetables, lentils and fish. Portion control and balanced meals are necessary.

• Gradually increasing the level of physical activity like walking, jogging, swimming, weight training.

• Counselling and a support system, including family and peers, to address emotional triggers, anxiety, and stress. A good quantity of sleep is important.

• Self-motivation, self-monitoring of daily calorie intake, routine weight assessment, monitoring physical activity levels and off-course mindfulness practices like meditation and nature bathing.

• Metabolic surgery in case of severe obesity, recommended by professionals.

7.Cognitive functions: In obesity, there are enough studies to show that there is a risk of cognitive decline. There are several ways to improve cognitive functions, such as:

• Controlling neuro-inflammation by medically managing any signs of systemic inflammation, controlling blood sugar levels and managing triggers like stress and anxiety.

• Dietary changes like avoiding high-sugar foods completely, processed foods and focusing on nutrient-rich, low-calorie foods.

• Exercises like cardio workouts to increase blood flow to the brain, which helps flush toxins, help to grow the size of the hippocampus to improve memory.

• Continuous physical activity by avoiding sitting for long hours; constant physical activity apart from routine exercise to clear brain fog. Weight training regularly, which helps to boost BDNF. Improving sleep quality.

• Trying to adopt intermittent fasting, which can help reduce brain inflammation.

8. Rewiring the brain for behavioural modification: To break a behaviour pattern which has been practiced for a long time is a difficult task, requiring patience and effort. Understanding and self – assessment are key pillars.

• Understanding the stress triggers, hunger signals, and habit loops to know the emotions behind them. To change neural pathways, repetition of a corrective behaviour pattern each time such a trigger arises is necessary to rewire the brain.

• Practising mindfulness to activate control of your brain to quiet the default false hunger signals and stress triggers.

• Changing eating habits to healthier options like whole grains, fibre-dense foods, portion control and cutting down on sugary or highly processed food to prevent dopamine spikes.

9. Managing hunger signals and habit loops: Not all hunger signals are real; some of them are false alarms just to activate your brain reward system. Some of the strategies are such as :

• Drinking water or sipping green tea or black coffee to fill the stomach.

• Eating small portions of meals every 3-4 hours instead of heavy meals.

• Practise physical activity throughout the day, like light exercise, walking and avoid sitting for long hours.

• Engage in activities and hobbies apart from routine chores or office work to keep the mind distracted from hunger signals.

• Lower stress by practising deep breathing exercises.

10. Takeaway: Research has shown that a high Body Mass Index (BMI) is associated with cognitive decline, reduced brain volume, and tissue atrophy in the frontal lobes and hippocampus. Excess weight also contributes to the degradation of the corpus callosum, which connects the two hemispheres of the brain. However, it is possible to reverse these effects by losing weight and making lifestyle changes, including adjustments to behaviour and eating habits. This process is gradual but rewarding and requires self-motivation, as well as support from family and peers, to break old habits and develop new neural pathways. In extreme cases, medical interventions such as anti-obesity medications or surgical procedures may be necessary if clinically recommended.

Thanks for reading.

Peace and love 🙏

10 facts: Are Artificial flavouring substances safe?

by drjurisharma, posted in Artificial flavours, flavouring compounds, chemical compounds, vanilla extract, natural flavours, artificial sweeteners, sugar, chemical engineered foods products, organic foods, Blog, brain, Brain, nervous system, gastrointestinal disease, autism, cancer, canned food, cognitive health, dairy, curd, yogurt, deep fried food, Food, Gut friendly, microbes, healing, health, Lung cancer, milk, dairy, curd, yoghurt, Nature,, Science, self healing, wellness

1. Artificial flavouring substances are usually used in foods, beverages and some medicines too, to enhance the taste, aromas, natural-like flavours and to extend the shelf life. These artificial flavouring substances are chemical compounds produced in the laboratory to give characteristic taste and smell. Unlike natural flavours, which are naturally available, these chemical compounds are made from petroleum or synthetic agents and mixed with alcohol or propylene glycol, which acts as a solvent. The process of making and purifying artificial flavours has to maintain safety protocols, and the standards are approved by the Food and Drug Administration (FDA) and other Food authorities.

2. Laboratory-made chemical compounds are easy to extract, less expensive and can mimic the required taste and smell. Widely used in products like bakery items, processed food, candies, beverages, processed meat and dairy items. Some of the common examples of artificial flavours are:

• Ethyl vanillin, which mimics natural vanilla

• Ethyl propionate, which gives a fruity flavour

• Benzaldehyde, which gives a cherry flavour

• Diacetyl, which mimics a buttery flavour

• Smoke flavourings are smoke obtained from heated steam from wood, a mixture of carboxylic acids and phenolic compounds.

3. Natural flavouring /Artificial flavouring: Natural flavourings are nature-derived compounds from plants and animal sources, obtained by extraction and distillation through physical, enzymatic and various microbiological processes. Such as vanilla derived from natural vanilla pods, citral from lemongrass.

Artificial flavouring substances are synthetic chemical compounds which are nature-identical but not natural substances. They are produced in the laboratory by many chemical-engineered substances by flavouring preparations, thermal processes, distillation, smoke flavourings and flavouring precursors. Examples of artificial flavours are vanilla flavour derived from ethyl vanillin, Methyl anthranilate which mimics grape flavour, and isoamyl acetate, which mimics banana flavour. Artificial flavours are preferred more than natural flavours as they are cheap, easily available and easier to produce in a laboratory.

4. Artificial flavourings are safe as long as they meet strict safety regulations and are approved by different regulatory bodies and Food Safety International expert committees. Some of the well-known regulatory bodies are:

• US FDA (Food and Drug Administration)

• EFSA (European Food Safety Authority)

• International Expert Bodies like FEMA (Flavour and Extract Manufacturers Association), JECFA (Joint FAO/WHO Expert Committee on Food Additives).

• Country-specific authorities such as FSSAI (India’s Food and Safety Standards Authority), BfR (German Federal Institute of Risk Assessment).

5. Why artificial flavours? The main goal behind using artificial flavours in various food items, bakery products, and processed foods is to mimic a certain flavour, taste, smell, and crunchiness, which makes a person crave such items and stimulates the sensory organs. While consuming any kind of food, the taste receptors detect certain compounds in that particular food item and send a stimulus to the brain via nerves, which actually create the sensation of taste. So, artificial flavours are engineered in such a way that they can create a specific taste similar to a natural flavour and stimulate the taste receptors so that the person becomes addicted to that particular food item.

6. Artificial flavours and health: Though artificial flavours are safe in small quantities for consumption, some side effects are reported, such as allergic reactions, headache, fatigue, stomach pain, dizziness and chest pain. Some studies have shown a link between certain diseases and artificial flavours such as:

• Artificial flavouring compounds like diacetyl can be carcinogenic and pose a health risk.

• Artificial flavours and artificial sweeteners are found to disturb the gut bacterial flora. But more studies are required in this topic.

• Artificial colour (yellow) tartrazine is linked to allergic reactions.

• Artificial flavours and colours are linked to affecting brain health, memory and ADHD in children.

• Addiction and obesity are issues that have been linked to artificial flavours in some research and can affect the brain. The taste bud receptors send signals to the brain, which in turn releases dopamine to give pleasure. Some studies show that artificial sweeteners affect the hunger and satiety centre and lead to weight gain.

7. A wide range of products where artificial flavours are mostly used include:

• Snacks: Cookies, candies, shakers, chips and many snack items.

• Soft drinks and energy beverages.

• Bakery items.

• Dairy items like yoghurt, ice creams, flavoured milk.

• Processed meats.

• Sauces, mayonnaise, ketchups, dressings.

8. Common names of artificial flavours which should be known by individuals so that they can be aware and selective while buying snacks, bakery or processed food in a supermarket.

• Ethyl vanillin, ethyl maltol, ethyl propionate.

• Diacetyl

• Benzaldehyde

• L-menthol

The best way to avoid eating artificial flavours and colours is to select minimally processed food items, plain dairy products, whole foods, unprocessed meat items and preferably organic food items.

9. Safe quantity: There is no standard safe quantity of artificial flavours and colours worldwide. But there are international committees, food regulatory authorities, and other regulatory bodies in each country to regulate the quantity of artificial flavours used in each of the food items before they go for consumption. Acceptable Daily Intake (ADI) limits are set for compound-specific limits, which are standardised by local food safety authorities and are decided by strict testing and toxicity tests before approval.

Wholesome food/ Natural Foods

10. Takeaway: Artificial flavouring is very common in a wide range of food items. Realistically, you may not completely avoid food flavourings. But it is always a wise choice to prefer natural wholesome food items to processed flavouring food items as far as health is concerned. Moreover, both artificial and natural flavourings have similar effects on health, as one cannot rule out which is healthier or safer. Therefore, it is a matter of habit formation and lifestyle choices for individuals, parents and children to learn to make healthier choices for wholesome food and minimal use of processed food items.

Thanks for reading.

Peace and love 🙏

10 facts : Why sea buckthorn has gained popularity?

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, brain, Food, Fruits, veggies, berries, hair, healing, health, life, meditation, inflammation, disease, physical health, mental health, wellbeing, Nature,, Omegas, fatty acid, Science, Sea buckthorn, Siberian pineapple, sand thorn, berries, super fruit, antioxidants, flavonoids, vitamin , supplements, diabetes, heart, hypertension, high cholesterol, high BP, anti inflammatory, metab, self healing, Skin, hair, wellness

1.Sea Buckthorn (Hippophae rhamnoides) is a shrub with yellowish-orange berries, a native of Southeast Asia and Europe. Other names used are sea berry, sand thorn and Siberian pineapple. Recent research has highlighted the tremendous health benefits of the fruit berries grown on this high-altitude shrub, which has been quite common on the Himalayan steep slopes for centuries. This shrub and its fruits are not new to the natives living in those regions. But, suddenly, it has gained much popularity due to its label as “Super food” by the recent scientific studies. The berries of this shrub are identified to have about 190 flavonoids and polyphenols, rich in Omega fatty acids and 15 times more vitamin C than oranges.

2. Sea Buckthorn’s nutritional profile stands out among many fruits and berries provided by the plant kingdom. It is considered a “superfood” for its amazing nutritional value.

• These berries have a rich supply of fat-soluble vitamin A, such as Beta-carotene (due to the orange colour), lycopene and Zeaxanthin.

• Vitamin E includes 8 natural variants, the tocotrienols.

• Vitamin K2 in natural form, which is quite rare in plants.

• Plant-based Omega 3, 6, 9, which is a complete omega fatty acid profile.

• Omega 7, which is Palmitoleic acid, is a rare variant.

• Vitamin C, which is 15 times more than that of a typical orange.

• Multiple bioactive compounds like flavonoids, phytosterols, organic acids and Tanins.

3. Heart-friendly: One of the main reasons for Sea Buckthorn berries’ attraction is their profound benefit to cardiovascular health.

• The Omega profile and bioactive compound help to lower LDL cholesterol, prevent plaque buildup, and lower blood pressure.

• Improve Cholesterol: Phytosterols reduce cholesterol absorption, LDL and triglycerides in the gut and maintain the level of good cholesterol, HDL.

• Relaxes the blood vessels and lowers the blood pressure.

• The antioxidant properties prevent LDL plaques from being deposited on the arterial wall and lower the risk of atherosclerosis.

• Reduces the risk of thrombosis by thinning the blood due to antiplatelet aggregation properties.

4. Diabetes: Studies have proven that sea buckthorn berries, due to their powerful antioxidant profile, help in the management of type 2 diabetes. Here are some of the potential benefits:

• These berries improve the metabolic function and lower the fasting blood sugar levels.

• Helps the body to improve insulin sensitivity and lower the resistance in due course.

• Its anti-inflammatory properties help to fight inflammation and prevent organ damage, which is a characteristic of diabetic progression.

• Reduce the damage to the beta cells of the pancreas, which produce insulin.

• Promotes heart health, which is otherwise a cardiovascular risk for diabetics.

• Boost immunity, which is important for diabetics or anyone with a chronic illness.

5. Metabolic disorder: Collectively, metabolic disorders include obesity, hyperglycaemia, high blood pressure, and dyslipidemia. The different ways of managing metabolic syndrome can be controlling blood sugar, lowering insulin resistance, improving dyslipidemia, reducing abnormal lipogenesis, lowering blood pressure and also improving gut health. The rich nutritional profile of sea buckthorn, which contains various flavonoids, omega fatty acids, and vitamins, helps to promote a positive impact on metabolic activities and prevent complications in metabolic pathways in such individuals.

6. Other amazing benefits :

• Aids cancer therapy: Studies have shown that flavonoids such as quercetin, kaempferol, and isorhemnetin present in sea buckthorn berry juice and oil extract can induce a cytotoxic response and prevent cancer cells from multiplying.

• Skin / cosmetic uses: Due to their rich nutritional profile of vitamins and omega fatty acids, these berries promote skin health, promote hair growth, increase blood circulation and reduce signs of ageing.

• Effective in promoting gut health and liver health by lowering liver inflammation, fibrosis and scarring.

• Disease prevention: Sea buckthorn, due to flavonoids and antioxidants, prevents free radical damage, reduces oxidative stress and lowers the risk of chronic diseases.

7. Interaction: Sea buckthorn berries are usually safe, and there is no evidence of adverse side effects. But due to its rich content of various nutrients, there may be drug interactions, and precautions are necessary:

• People with bleeding disorders and those undergoing surgery should avoid situations where there is a risk of slowing blood clotting, bruising and bleeding.

• Anticoagulant and antiplatelet drugs can interact with sea buckthorn and pose a risk of bleeding.

• People on high blood pressure medication should avoid it as they can further lower their BP.

8. Uses: The raw berries are sour and acidic in taste. So, it is not usually consumed raw; instead, it is converted into functional foods.

• Juices and pulp: They are diluted in water before drinking and used in pies, desserts, jams and herbal teas.

• Oils are used in the form of capsules as a vegan Omega fatty acid source, used in hair and skin wellness.

• Powders: As supplements in drinks, smoothies and teas.

9. Availability: Sea buckthorn berries are available in local markets specific to the native regions of Asia -Pacific where they are grown. Otherwise, they are available as products in supermarkets, stores, and retail in different brands. It is important to buy from known, reputable brands for safety issues.

They are available in juices (cold-pressed is best), pulps, dried berry powder, gummies, tablets, capsules and in oil extract. Due to their nutritional value, the products are widely used and have been quite popular.

10. Takeaway: Sea buckthorn berries have been used for centuries by the native people of mainly Asia, especially in the Himalayan regions, Ladakh, China and European regions. But recent scientific studies and research have identified its rich nutritional profile, which has attracted the attention of health enthusiasts. Therefore, these tiny berries have become popular, and the products are selling widely nowadays. No doubt, sea buckthorn is, indeed, a super fruit and its intake in moderation, in whatever form, can be helpful for overall health and wellness.

Thanks for reading.

Peace and love 🙏

10 facts : Although honey 🍯 is similar to sugar, why it is still considered a healthier option ?

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Bee,, Blog, brain, Brain, nervous system, gastrointestinal disease, autism, cancer, cognitive health, Cooling, freezing, storage, Food, Gut friendly, microbes, healing, health, Heart friendly, weight friendly, gut healthy, constipation,, Honey, beehives, polyphenols, antioxidants, anti inflammatory, cough, cardiovascular diseases, neurological diseases, Nature,, Science, self healing, wellness

1. Honey is about 80% sugar, mostly fructose and glucose and is considered a natural sweetener. Since it is a derivative of plant nectar, it is a storehouse of bioactive compounds like polyphenols, flavonoids, vitamins, minerals and antioxidants. It is a blend of many natural substances, depending upon the different varieties of flowers whose nectar is collected by the bees. Because of its nutritional profile, honey has tremendous health benefits and is considered a healthy sweetener.

Beehives

2. Though honey is rich in sugar, it is a powerhouse of nutritional content in raw, unprocessed form. Depending upon the sources, the nutritional content can vary. Pasteurised honey is processed, filtered and can have a lesser quantity of flavonoids and polyphenols. Besides the antioxidant properties, honey includes calcium, potassium, vitamins, copper, iron and zinc. It also contains a trace amount of protein. Depending upon the varieties of flowers’ nectar, climatic conditions, examples of honey varieties are:

• Clover honey

• Wildflower honey

• Orange blossom honey

• Alfaalfa honey

• Buckwheat honey

• Rare variety like Manuka honey, found in New Zealand

3. Sources: Honey is the only natural sugar source which is produced by insects that humans consume. It is best when consumed raw and unrefined. Supermarket honey available is usually processed, pasteurised honey. Honey should be best sourced from local markets and local farmers, where the content is “pure honey” without any additives. These types of honey are lighter in colour and consistency. Darker varieties are stronger in flavour and nutritionally rich. Honey should be preserved in a glass bottle or plastic airtight container, below 32 degrees F.

4. Crystallisation: This is a natural process of honey where it is transformed from a liquid to a solid state depending upon the temperature and how it is stored. Crystallisation of honey doesn’t mean that the honey is spoiled. Honey with a higher content of sugar (fructose, glucose) is quickly crystallized like Alfalfa and clover types. Crystallisation happens as the dense sugar molecules start to hold the water permanently, which is, in fact, a sign of pure, unadulterated honey. The honey can be restored to its liquid form by putting the honey jar in a warm water container. Boiling water should be avoided as the nutritional content can be compromised.

5. Storage: Honey doesn’t require refrigeration. Its shelf life is around 2 years. Refrigeration and cold temperatures can lead to crystallisation of honey. It can be stored at room temperature at 20 to 25 degrees C or around 60 degrees F, ideally in an airtight glass container. It can also be stored in a food-grade plastic container. In the kitchen, it can be placed in a dry, dark place or pantry, avoiding direct sunlight.

6. Health benefits: As honey is rich in sugar, it should be consumed in small quantities rather than in large amounts. For centuries, the latest research has shown that honey has promising health benefits and healing properties. Some of them:

• Antioxidant rich so consuming raw, unrefined honey on regular basis can have anti-inflammatory benefits.

• Promote balance of blood sugar levels than regular refined sugar.

• Improves heart health by maintaining blood pressure, regulate heart beats.

• Since it has anti-bacterial properties , it can promote wound healing.

• Suppress sore throat and cough and support respiratory health.

• Supports gut health and is helpful in case of irritable bowel disease.

• Anti-fungal, anti-bacterial & anti-cancer.

7. Brain health: Research suggests that honey has amazing benefits for brain health and can prevent neurodegenerative diseases. Manuka honey is the best for brain health. Some of the neurological benefits of honey are:

• Unlike a refined sugar rush, honey can provide a natural, steady energy flow to neurons.• Flavonoids and phenolic acids can prevent free radical oxidative stress and cell damage in neurons.

• Supports memory by protecting brain cell mitochondria and elevates BDNF (brain-derived neurotrophic factor).

• Studies show honey is neuroprotective and prevents cognitive decline.

• Honey naturally contains melatonin, which supports sleep, and naturally removes toxins from the brain that build up while awake.

8. Alleviate cough: Studies have shown that honey is effective in soothing a cough. Drinking honey with a little warm water during a cough can help to form a coating in the throat. Its anti-bacterial and anti-inflammatory properties help as a healing aid for infections. Moreover, honey is safer as a home remedy than over-the-counter medications. It can be given to all age groups except children below 1 year of age, when there is a risk of food poisoning. Research shows that honey is far better than medicines like diphenhydramine (anti-histamine) and has a similar effect to drugs like dextromethorphan (cough suppressant ) and Salbutamol ( asthma drug).

9. Though honey is a natural sugar alternative, it is usually safe and healthy for daily consumption in moderation. There is no such standard recommendation, but experts suggest that 6-7 teaspoons daily should not be exceeded. WHO guidelines suggest that daily consumption of free sugar should not exceed 10% of daily intake. Since it has therapeutic benefits, its daily consumption can be beneficial for both gut health and the immune system. While using honey as a sugar substitute, other refined sugar food items should be completely avoided, as there are chances of weight gain (due to extra calories), sugar spikes in insulin-sensitive diabetics.

10. Takeaway: Research has shown for decades that honey is healthy with tremendous therapeutic effects when consumed in moderation as a wellness habit. Honey can replace the intake of refined sugar in several ways, such as:

• For dessert, yoghurt or breakfast bowls.

• Herbal teas, green teas.

• Morning, on an empty stomach with warm water as an aid to digestion and immunity.

• Honey should be avoided in boiling water or while cooking, as it may damage its nutritional value.

Thanks for reading.

Peace and love 🙏

10 facts : Nitric oxide (NO) is body’s power source 💪

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, brain, cognitive health, Food, healing, health, Heart disease, Nature,, Nitric oxide, NO, gas, vasodilation, cardiovascular system, heart, body, lungs, brain, endurance sports, athletic ability, erectile dysfunction, blood vessels, Science, wellness

1.Nitric oxide is a gas that is naturally produced by our body. Its basic function is to relax the blood vessels, which in turn transport the blood, oxygen and nutrients to the different organs and cells of the body to function smoothly. Nitric oxide is a vital nutrient as it protects the layers of cells in the blood vessels. It regulates the cardiovascular system, immune system, and nervous system. When nitric oxide is scarce in the body, it leads to a condition called endothelial dysfunction, which can risk the cardiovascular system.

2. Nitric oxide, as a powerful molecule, has many protective health benefits and is vital to human health. The potential benefits are:

• Cardiovascular system: Since it is a vasodilator, it lowers the blood pressure, relaxes the blood vessels, ensuring a smooth transportation of blood throughout the body.

• It lowers the inflammation in the body as it acts as an antimicrobial agent, a free radical agent.

• Neurological system: It is a neurotransmitter and helps in communication between nerve cells.

• It helps in exercise endurance as an oxygen delivery agent and improves athletic performance.

• It helps in treating erectile dysfunction.

3. Diverse physiological role: The NO (nitric oxide) molecule is synthesised from L-arginine in the tissues of the body by using the iso-forms of nitric oxide synthase. As mentioned before, NO gas is important in maintaining the endothelial layers of the blood vessels, as well as the blood flow through the vessels, and also inhibiting the activation of blood platelets. NO activates an iron- containing protein and helps to bind with haem. It regulates the immune system as a primary defense mechanism against attack by microorganisms. It acts as a neurotransmitter for nerve cells of certain types. NO activates several cellular activities.

4. Physical endurance and Nitric oxide: Research studies have clearly shown that Nitric oxide (NO) plays an active role in vasodilation, improves and enhances blood flow through blood vessels, organs and in mitochondrial respiration. Thereby, it promotes sports performance, endurance and aids in the healing and recovery of tissues. Nitric oxide and physical activity are very closely related. Evidence-based studies have shown that exercise helps to increase the level of nitric oxide, so it is highly recommended for athletes and patients with cardiovascular disorders.

5. Nitric oxide and erectile dysfunction: Erectile dysfunction is mainly caused by impaired nitric oxide bioactivity. The nerves and endothelial cells release nitric oxide when stimulated, which causes vasodilatation of blood vessels and relaxation of smooth muscles. When there is low nitric oxide production, it results in impaired vasodilation and endothelial dysfunctions, causing erectile dysfunction. Common risk factors are high blood pressure, diabetes, smoking and aging.

6. Nitric oxide as a neurotransmitter: Since it is a gas, it acts as a free radical and is synthesised in response to neural activity rather than stored in synaptic vesicles. It can diffuse rapidly through cell membrane barriers and can reach several neuronal and non-neuronal cells in multiple locations. It can act in intracellular targets on both pre-synaptic and post-synaptic neurones to stimulate neurotransmitter release and enhance synaptic plasticity. But excess nitric oxide can cause neurotoxicity, like in Alzheimer’s and Parkinson’s disease.

7. Sources: Nitric oxide naturally releases from oceans, soil bacteria, and the atmosphere by oxidation of ammonia and animal wastes. Some other sources are forest, wild vegetation, fertilizers, fossil fuels combustion and other industrial processes.

The primary source in the human body is the conversion of L-arginine (an amino acid) by enzymes, which releases nitric oxide internally. The different food sources of Nitric oxide are Beetroot, garlic, meat, poultry, leafy green vegetables, citrus fruits, nuts and seeds.

8. Nitric oxide supplement: A healthy, balanced diet rich in vegetables, poultry, and meat is enough to provide the necessary nitrites and nitrates to produce enough nitric oxide for the body’s requirements. If the body’s nitric oxide levels are low, your health care provider might give you nitric oxide supplements. They usually contain the synthetic version of the compounds, which can help the body to produce the optimal level of nitric oxide. Supplements are generally safe when taken under expert supervision and in an appropriate dosage.

9.Side-effects: Nitric oxide supplements, as mentioned above, are considered safe when taken under medical guidance. Overexposure and overdosing may cause side effects:

• Physical symptoms include nausea, vomiting, headache, and stomach upset.

• Heart palpitation, dizziness, lightheadedness, sudden drop of blood pressure.

• Interaction with other medications, such as blood pressure medication and erectile dysfunction medication, can cause a serious risk.

• Overexposure can cause coughing, shortness of breath, and lung injury.

10. Some of the known nitric oxide supplements are:

• Arginine

• Citrulline

• Nitrates

• Vitamin C, flavonoids, and polyphenols make nitric oxide easily available for the body for different purposes.

Doses depend on the individual requirements and the compounds of the supplement.

Thanks for reading.

Peace and love 🙏

10 facts: Which type of cocoa is healthiest ? ☕️🍫

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, Blood sugar levels, diabetes, exercise insulin levels, insulin sensitivity, brain, Cocoa powder, cacao, chocolate, chocolate powder, baking, sugar, cocoa beans, cocoa butter,, Food, healing, health, Science, wellness

1.Like chocolate, cocoa powder is a common item which sits in the pantry of most households. It is widely used for either baking or having a chocolate drink. But what is cocoa powder? Cocoa beans are usually ground into a paste called chocolate liquor, which is later sweetened or added with other ingredients to make different types of chocolate. The paste or chocolate liquor is rich in cocoa butter, which can be de-fatted by further pressing and made into a finely ground powder, called natural cocoa powder.

2. Cocoa powder is of different types depending on the method of processing:

• Natural cocoa powder is de-fatted, finely ground cocoa nibs. This way they retain the original acidity, flavours and aromas. They appear light brown in colour.

• Raw cocoa powder is produced by cold pressing the cocoa beans without any chemicals being used. This has the highest nutritional value and antioxidant levels.

• Dutch-processed cocoa powder is processed by alkalizing the cocoa nibs with potassium carbonate. In this process, the colour deepens, and acidity reduces. This is how dark chocolaty colour and flavour are gained.

• Black cocoa is achieved by further alkalizing the cocoa nibs with a heavy dose of potassium carbonate, which gives the characteristic black colour famously used in Oreo cookies.

Different types of cocoa powder

3. Cacao powder v/s cocoa powder: Though both of them have the same source as cocoa beans but the treatment of processing are different. Cacao powder is processed from unroasted cocoa beans at low temperatures, so they appear lighter, bitter in taste and pure. They retain the highest nutritional content and are very rich in antioxidants. Whereas, cocoa powder is ground from roasted cocoa beans, so it appears darker, less bitter in taste and has less nutritional content. Therefore, cacao powder is actually healthier than cocoa powder as far as health benefits are concerned.

4. Caffeine in cocoa: Cocoa beans naturally contains 0.1 -0.7% caffeine. About 0.3% caffeine is also present in the skin surrounding the cocoa beans, so at least 1.2 % caffeine is present altogether in cocoa beans, less than dry tea leaves, which is around 3-4%. Other stimulants like theobromine and phenylethylamine are also found in cocoa beans, which can influence the mood and energy levels in a mild way. But compared to coffee, the stimulant effect on the brain and body is much less.

5. Nutritional facts: Cocoa powder is a nutritional powerhouse of many healthy compounds and antioxidant properties.

• Cocoa butter, which is present in cocoa beans, is a combination of oleic acid, stearic and palmitic acid. Oleic acid is a monounsaturated fatty acid and is heart-friendly.

• Minerals: Cocoa powder is rich in minerals like magnesium, iron, calcium and potassium. It is also rich in vitamin B.

• Anti-oxidants: Rich in polyphenols, especially flavonoids, which protect the body from free radical damage.

• Fibre: Cocoa powder is rich in plant-based fibre, good for gut health.

6. Though cocoa is famous for its chocolate and chocolate-based products, research shows that the compounds found in cocoa, like polyphenols and flavonoids, have antioxidant and anti- inflammatory properties and are beneficial for the human body. But the processing and different treatments used in the manufacturing process of chocolate and its products might lower the beneficial and nutritional properties. Heating and processing cause loss of antioxidants and anti- inflammatory properties. Further, adding sweetening agents, artificial flavouring agents while processing can damage the valuable content of natural or raw cocoa and may no longer prove to be useful in terms of health. Therefore, not all types of chocolate or chocolate products can be termed healthy in today’s times.

7. Potential benefits of cocoa powder, natural and raw form, produced by crushing cocoa beans, can have various health benefits:

• May lower the risk of cardiovascular diseases, heart attack and stroke.

• May lower the high blood pressure by lowering the nitric oxide levels.

• Improves blood circulation in the brain and nervous system, elevates the mood.• Improve symptoms of type 2 diabetes.

• May contain cancer-preventive properties.

• May boost the immune system due to the presence of minerals.

• It may help in weight management.

8. Side effects of cocoa powder:

• Caffeine: Having too much caffeine in cocoa can lead to irritability, a fast heartbeat and tremors.

• Medicine interaction: Cocoa can interfere with blood thinners (Warfarin) and may increase bleeding risk.

• Allergy: Cocoa can cause digestive issues, allergic reactions like hives, itching or migraine in some individuals, though quite rare.

• Heavy metals: Some brands of dark chocolate may contain high levels of lead and cadmium, which can be harmful to the brain, especially in pregnant women and children.

• Kidney stones: Regular intake should be avoided by individuals who are prone to calcium oxalate stones. It is important to avoid the daily intake of dark chocolate due to its high oxalate content.

9. Cocoa beans are fermented, dried, roasted, and then ground into fine powder, which is why adding cocoa powder to the diet can be a better option than having dark chocolate bars or chocolate varieties available commercially. Cacao and cocoa powder can be incorporated in the diet to avail the potential health benefits, though in moderation –

• Adding to breakfast cereals, smoothies, yoghurt, or having a hot chocolate drink.

• Using raw cocoa powder in baking recipes like cookies, cakes, granolas, and brownies.

• Eating dark chocolate bars that have 70-80 % cocoa, which have no heavy metals used, can be a healthy treat as well.

• Adding cocoa powder to your face mask, in your daily skin routine, can reduce hyperpigmentation, moisturise the skin, and reduce acne.

10. Takeaway: Yes, natural and raw cocoa powder, cacao powder are healthy in terms of their rich nutritional contents like polyphenols and flavonoids. But, diverse chocolate varieties and chocolate bars commercially still contain a significant amount of sugar, additives, artificial flavoring agents, fats, and heavy metals, which, otherwise, can be more harmful than useful to the human body. So, it is important to consume cocoa products in moderation and to properly read the labels before buying. Since there is such a wide variety of dark chocolate and even different types of cocoa powder available, moderation is the key. A recommended dose of about 20-30 grams per day of dark chocolate can give the essential benefits. Due to its caffeine content, consuming cocoa products late in the evening should be avoided as it can cause sleeplessness and irritability.

Thanks for reading.

Peace and love 🙏

10 facts: Sleep wake cycle linked to cortisol 👐

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, Blood sugar levels, diabetes, exercise insulin levels, insulin sensitivity, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, cognitive health, Cortisol, stressful, stress, sleep, sleep deprivation, anxiety, depression, wakefulness, hormones, melatonin, fear, pain, emotions, Food, Gut friendly, microbes, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, mental health, muscle, body, nature, self healing, spiritual, Supplement, wellness

1.Cortisol is a stress hormone released from the adrenal glands, which is ideally secreted during a fight-or-flight response. However, in today’s world, our daily lives are filled with stressful situations, such as competition, comparisons, peer pressure at work, negative people, and relationships stress. As a result, cortisol is released not just in short bursts but remains chronically elevated. This persistent high level of cortisol keeps the body in a constant state of stress, leading to chronic inflammation, sleep problems, and various diseases.

2.Cortisol plays essential role in the body for survival. But when cortisol is elevated for a longer period of time can lead to health issues like weakened immunity, metabolic syndrome and mental health issues. The functions of cortisol are :

– Maintaining blood pressure

– Elevating blood sugar levels

– Regulating the circadian rhythm

– Facilitating the utilisation of energy from carbohydrates, proteins, and fats

– Reducing inflammation

3. Sleep-wake cycle follows a synchronised rhythm with the night and daytime. During the sleep phase, the body goes through different stages, such as:

• Non-REM stage: The phase where the body and mind, being awake, slowly move to a calmer state before falling asleep. Followed by a stage where the body’s core temperature drops, brain waves slow down. After this, a stage emerges where the heartbeat, breathing, and brainwaves slow down, entering a deep state of relaxation.

• REM state: This stage occurs normally after the deep sleep phase. In this phase, people have vivid dreams, and intense dreaming appears. There is weakened muscle activity similar to temporary paralysis. This stage is important as the brain is cleaning out the buildup of waste and toxins.

4. HPA axis: The hypothalamic-pituitary-adrenal axis is responsible for the neuroendocrine regulation. Hormones like melatonin and cortisol from the HPA axis modulate the sleep-wake cycle. When there is disruption of this axis disturb the sleep cycle. Studies show that there are reciprocal interactions between sleep regulation and the HPA axis. Stressful situations like PTSD, emotional trauma, and chronic workload can lead to long-standing sleep issues like insomnia, sleep deprivation, and lack of restorative sleep, which in turn lead to disruption of the HPA axis and vice versa.

Insomnia

5. The HPA axis and sleep have a significant interconnection. Good quality sleep, deep sleep causes an inhibitory effect on the HPA axis, whereas hyperactivation of the HPA axis leads to overload of glucocorticoids, wakefulness, and loss of sleep. Sleep disorders related to HPA dysfunction are:

•Insomnia is a common sleep disorder which is found to have a connection with an increase in ACTH and consistent cortisol levels and arousal of the central nervous system.

•Obstructive sleep apnea or daytime sleepiness has been associated with elevated pro- inflammatory cytokines, IL-6 and TNF.

Weight gain

6. Elevated cortisol level: Studies show that sleep deprivation has a direct connection to elevated cortisol levels, long hours of wakefulness in the daytime, glucocorticoid overload, and disruption in the HPA axis. These directly affect the well-being of the individual and increase the risk of obesity and type 2 diabetes. Other symptoms of elevated cortisol levels are:

• Weight gain

• High blood pressure

• Weakness of bones

• Muscle weakness

Stressed

7. Cortisol level: Normally, there is a spike of cortisol level in the morning, known as the awakening response, and it continues for about 60 minutes thereafter. Then, gradually the level-starts dropping and reaches the lowest level towards the evening/midnight. The factors which can affect the cortisol levels are:

• Stress

• Disturbed routine sleep schedule

• Morning light may cause the surge

• Cushing’s syndrome

Overworked/ stressed

8. Stress and cortisol level: Cortisol is a steroid hormone which is released from the adrenal glands in the body’s response to stress. Cortisol also releases sugar from the liver to combat stress. In addition to this, sleep and stress are also closely linked. Prolonged stress can lead to sleep disorders like acute insomnia. The types of stress when cortisol is secreted are:

•Short-term stress

•Long-term stress

•Trauma, both psychological and physical.

Dark chocolate

9. Food and cortisol: Certain foods can support gut health, reduce stress and lower the cortisol level naturally:

• Whole grains and natural fibres – Whole grains are rich in polyphenols, which can support gut health and reduce stress and cortisol. Fibrous foods like vegetables, fruits, and berries contain both polyphenols and antioxidants that help reduce cortisol levels.

• Dark chocolate (70 – 80%) – Flavonoids in dark chocolate can lower the stress response and cortisol from the adrenal glands.

• Green tea contains polyphenols, catechins, and L-theanine, which can lower stress reactivity.

• Probiotics/Prebiotics are linked to healthy gut health, reduce stress and cortisols.

• Healthy fats in nuts, fatty fish, and seeds rich in omega3-fatty acids reduce stress and support mental health.

• Water – Consuming water throughout the day prevents dehydration and controls the cortisol level.

Meditation
Community/ kindness/ volunteer work

10. Natural habits that can keep the cortisol level under control:

• Good sleep routine – Firstly, keep away from cell phone or any kind of distraction at least 1 hour before bedtime, avoiding alcohol, caffeine intake and nicotine 5-6 hours before bedtime, maintain a bedtime schedule; going to bed and waking up the same time every day is important for sleep hygiene.

• Daily routine exercise, nature bathing, walking or any kind of physical activity.

• Practise deep breathing techniques like Pranayama, mindfulness breathing, Meditation, yoga, tai-chi.

• Maintaining your mental health by managing your personal relationships, staying away from negative people and a negative environment, cultivating hobbies, laughing, and listening to music.

• Spirituality – believing in spiritual faith, attending spiritual workshops, meditation, community spirit, kindness /charity /voluntary works, helps maintain cortisol levels.

Thanks for reading.

Peace and love 🙏

10 facts: Why mitochondrial health is of crucial importance?

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, brain, Brain, nervous system, gastrointestinal disease, autism, cancer, cognitive health, Food, Fruits, veggies, berries, healing, health, Heart disease, Inflammation, diseases, environmental damage, health issues, life, Mitochondria, mitochondrial disease, mitochondrial health, Physical activity, exercise, strength training, walking, meditation, Supplement, Supplement, Coenzyme, Q10

1. Right from the biology textbooks in school, to higher levels of studies and research, the importance of mitochondria has been highlighted time and again. As previously mentioned, mitochondria are known as the ‘powerhouse’ of cells. They are the centre of energy production, metabolism, crucial for cellular functions, ranging from cellular activities, regulating vital functions and including cellular death. In other words, they are critical in maintaining overall health, preventing various diseases and increasing longevity.

2. Mitochondria have their own DNA and undergo a constant process of damage, repair, replacement, and distribution within cells of the body. Through mitochondrial dynamics, a damaged component or an impaired mitochondrion can be replaced, mitochondrial quality can be controlled, and mitochondrial functions can be maintained, thereby preventing disease processes and promoting overall health and well-being. So, continuous mitochondrial dynamics play a pivotal role in maintaining good health on the cellular level and overall longevity.

3. Mitochondria are an integral component of a cell that carries out a series of functions like cellular metabolism, energy production, fission, fusion, mitophagy, ion homeostasis, senescence and cell death (apoptosis). Studies have shown that mitochondrial dynamics play a pivotal role in diverse cellular functions, influencing the activation and functioning of cells and cell movement. Cell movement is the basis of vital processes like wound healing, tissue growth, the immune defence mechanism and disease-related processes like malignant metastasis. Therefore, mitochondrial health and functioning are fundamental to the body’s overall health at the cellular level.

Inflammation/chronic pain

4. Mitochondrial health impacts most of the vital systems of the body, including the immune system, bones, muscles, heart, neurological, cognitive and gut health. So, when mitochondria are dysfunctional or underperforming, the body will exhibit various symptoms like :

• Low immunity status.

• Metabolic syndrome

• Brain and cognitive disorder

• Fatigue syndrome

• Bone and muscle conditions like osteoporosis and sarcopenia.

• Inflammatory diseases.

• Chronic body pain.

Fatigued

5. Mitochondrial disorders are of two types: Inherited types and acquired types. Inherited Mitochondrial disorders can be caused by genetic mutations due to defective genes encoding the ETC (Electron Transport Chain) protein.

• Barth syndrome.

• Kearns- Sayre syndrome.

• Chronic progressive external ophthalmoplegia.

• Leigh syndrome.

• Ataxia.

Acquired types: Mitochondrial disease from external factors like toxins, drugs (mitotoxins), ageing, infections, inflammatory responses, secondary causes like cancer, Alzheimer’s disease, diabetes, Parkinson’s disease, long-standing COVID.

Body aches

6. Symptoms of mitochondrial disorders depend on the underlying factors, such as:

•Inherited types usually affect multiple organs, such as the brain, heart, liver, and muscles.

•People may have muscle fatigue, cognitive decline, hearing loss, vision loss, and GI issues.

•Secondary types can be the consequence of the primary causes, like type 1 diabetes, cancer, mental health disorders, and heart diseases.

•Environmental factors like toxins and drugs may result in mitochondrial dysfunctions.

Acquired types may have both the symptoms of inherited types and the underlying primary cause.

Tiredness

7. Diagnosis and treatment depend mainly on the underlying factors, triggering causes and the primary disease. The diagnosis relies mainly on many criteria, such as clinical, biochemical, tissue, and molecular specificity of clinical and laboratory findings.Treatment depends on the family history, clinical findings, laboratory findings, and metabolic/ molecular diagnosis. Treatments are usually antioxidant intakes, regular calorie intake, exercise, and specific treatment depending on the primary disease and definite mitochondrial dysfunction.

Supplements/ antioxidants

8. Commonly used agents for the treatment of both inherited and acquired types are:

• Electron transport chain support, like CoQ10 (ubiquinol)

• Electron carrier support, such as Niacin and Riboflavin.

• Fatty acid oxidation support, Biotin L-carnitine.

• Enzyme co-factors like Thiamine, Pantothenic acid, Biotin, and Alpha-lipoic acid.

• Anti-oxidants like Vitamin E, C, L-carnitine, and CoQ10.

Holistic health

9. Mitochondrial diseases have no cure, but a holistic lifestyle approach can improve the quality of life. The focus is mainly on energy preservation, nutrition, exercise, and stress management.

• Conservation of energy is essential to reduce fatigue, like planning out the daily and weekly schedule, taking rest in between normal chores, using assistive devices to minimise effort, and seeking help to reduce workload.

• Balanced diet of healthy protein, whole grains, fruits, vegetables, and healthy fats. Hydration and using supplements for health support.

• Exercise may include moderate activity, such as walking, swimming, or aerobic exercise.

• Prioritising sleep, avoiding toxins like quitting alcohol and smoking, managing stress like meditation, mindfulness tools, and nature bathing.

Whole Foods

10. In a nutshell, mitochondrial dysfunction is very complex in nature and still not completely understood. Mitochondrial dysfunction is differentiated as primary and secondary (acquired) types, and the diagnosis is again very complex. But there is the MDC scoring system, which is beneficial. Millions of people across the world suffer from some types of mitochondrial dysfunctions, which include diabetes, autism, cancer, blindness, heart, kidneys, liver or infertility issues, Alzheimer’s, Parkinson’s and chronic fatigue syndrome. Bringing out lifestyle changes can be helpful to improve the quality of life as well as mitochondrial health.

Thanks for reading.

Peace and love 🙏

10 facts behind this human behaviour: Why act of cleaning is deeply satisfying?

by drjurisharma, posted in Behavior, cleaning, tidying, endorphins, stress management, psychological, emotional regulation, physical therapy, Blog, brain, emotional health, Emotional thoughts, fear, pain, emotions, healing, health, life, mental health, Science, self healing, Therapeutic, stressful, worldly chaos, challenging,, wellness

1. Organizing or cleaning your space, room, or home isn’t about tidiness, but being in control of a world that feels otherwise uncontrollable. It’s about a mental state with clarity, being organized and being at peace with oneself. Psychologically, the environment we live in reflects our mental state. In a world full of everyday stress, chaos, and overwhelming uncertainties, cleaning becomes a tool, a therapy to make ourselves feel organised, meaningful and at peace. Clearly, this act can help reduce stress hormones and release endorphins, which can lift the mood.

2. Many people, even after a stressful day, have a habit of cleaning and tidying their stuff after reaching home or their living space. Psychologically, when emotions are overwhelming and stressful, our brain tries to do things which are tangible, grounding, and clarifying, which makes us feel more in control. These actions give the brain a sense of relief and stability, an escape in an otherwise uncontrollable world.

3. In the brain, activities like reorganising the bookshelf, arranging the office table, cleaning and tidying the home, folding clothes in the closets, cleaning the kitchen, washing the dishes, vacuuming the floor stimulate the parasympathetic nervous system, the reward system, releasing dopamine, the happy hormone. These small acts instantly feel rewarding, light and happy. A tidy living space, home, or office gives the subconscious mind a feeling of security, stability, and organization.

4. Psychologically, on the flip side, a disorganised, messed-up space gives the mind a sense of cluttered thoughts, incoherence, ambiguity, confusion and anxiety. In an already stressful, loud world, you feel more overwhelmed, stressed, where things and people are unpredictable, uncertain and reactive. So, for a change, cleaning, organising, and rearranging makes people feel instantly happy, stable, predictable and certain.

5. Research shows that a cluttered, anxious, stressful mind raises the cortisol hormone. On the other hand, the environment we live in reflects our mental state. So, a messy, cluttered space clearly affects our mental state. The subconscious mind feels confused, lacks clarity, and is incoherent in a disorganised space. So, rearranging the room, furniture, things, clothes, books gives an instant emotional high, certainty and sense of control. The truth is, cleaning isn’t about habit, it’s about emotional regulation, choosing to change the emotional responses of stress, anxiety, chaos to stability, calmness and clarity.

6. Emotional regulation, by definition, is the ability to regulate our emotional responses from a state of uncontrolled, overwhelming situation by making behavioural changes with a healthy coping mechanism to a state of emotional grounding, stability and a sense of control. Examples of emotional regulation are deep breathing, going for a walk, journaling, light exercise and doing tasks like rearranging the books, furniture, cleaning the kitchen, doing the dishes and so on. It’s the ability to change a negative situation’s impact to a more productive and fulfilling one.

7. The strategies of emotional regulation can be summed up as :

• Recognise: Identifying the emotions like anger, anxiety, ambiguity and incoherence.

• Respond: instead of reacting negatively, changing the situation’s impact to a more productive, controlled and tangible behaviour like going for a short walk, rearranging the books on the shelf, cleaning the mess, folding clothes in the closet, cleaning or mopping the floor or any similar activity.

• Reappraisal, like changing the emotional response to more rewarding outcomes like stability, calmness, sense of control and certainty.

• Reflecting on the change of behaviour and situation gives deep satisfaction and happiness.

8. Activities like cleaning a room, realigning a corner, rearranging books, furniture, cleaning a countertop or mopping the floor are not just tidying or organising acts or behaviour but something more deeper as emotional relief or emotional satisfaction. It’s about reconnecting oneself, bringing a sense of control, stability in a world of external chaos, a stressful day or an overwhelming situation. So, for many people, organising and cleaning their home or their living space becomes a daily emotional ritual and therapeutic.

9. People who keep doing such activities, while they keep performing the acts, they also process their emotions, release the stressful thoughts, anxiety, ease the confusion, bringing more clarity and stability. In fact, by doing such activities, as the visual clutter slowly fades away by physical actions, internally, the mental clutter slowly subsides, emotions and thoughts become more under control, and thinking becomes clearer and regulated.

10. To sum it up, in a world full of uncertainties and unpredictability, organising, rearranging, and cleaning gives an instant outcome which the brain interprets as safety or being under control. When a book or a thing is placed exactly where it belongs, refolding a dress and placing it back in the closet, cleaning the otherwise dirty countertop, it’s like reconnecting with oneself, which gives the subconscious mind that instant boost or reward of comfort, safety and stability in an external world of chaos or an uncontrolled environment.

Thanks for reading.

Peace and love 🙏