Tag: digestion

10 facts: Why TUDCA is favorable? 🙌

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, Brain, nervous system, gastrointestinal disease, autism, cancer, Cholesterol, cognitive health, dairy, curd, yogurt, detoxification, vegetable,, eyes, Food, glutathione, antioxidant, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, mental health, Nature,, self healing, TUDCA, liver, bile salt, bile acid, brain, cells, eyes, antioxidants, free radicals,, wellness
Liver

1. TUDCA is tauroursodeoxycholic acid, which is naturally produced in the body as a short-chain bile acid that facilitates the breakdown of fats and helps in the absorption of nutrients. TUDCA is necessary for the metabolism of fats and oils that are consumed in the diet. Research has shown that TUDCA has amazing health benefits, promotes overall wellbeing by supporting the gut microbiome, and protects the nervous system, brain, heart and liver. Because of its health benefits, TUDCA is prescribed by health professionals, sometimes as a supplement. Though it was mentioned long before as traditional Chinese medicine, recent research studies have made it popular as a supplement for its tremendous health benefits.

Gut health

2. TUDCA for gut health: TUDCA is known to be hepatoprotective and prevents damage to liver cells. So, it shows promising results for those dealing with fatty liver, cirrhosis and hepatitis. As far as gut health is concerned, TUDCA has amazing benefits:

•It promotes the growth of good bacteria and maintains a balance in the biodiversity.

•It strengthens the immune system by promoting the growth of immune cells, of which around 80% are in the gut microbiome.

•It helps to tone down the inflammatory response in the gut and prevent chronic inflammatory conditions like leaky gut.

3. Other health-promoting benefits of TUDCA are:

• It protects the brain cells from damage by clearing toxins from neurons and supporting brain functions.

• It supports cardiovascular health by lowering LDL levels by breaking down and removing excess cholesterol.

• It lowers blood sugar levels by increasing the sensitivity of insulin in the cells and muscle tissues.

• It promotes free radical damage due to antioxidant properties, prevents cell damage and helps cell repair.

• Protects the liver from toxins from heavy metals, alcohol and medications.

• Support immune system by reducing inflammation.

Brain

4. TUDCA for brain: Research has shown many potential benefits to the brain and nervous

system, as it can cross the blood-brain barrier and can have antioxidant effects like cell repair, prevent cell damage and reduce inflammation. Some of the neuroprotective effects are:

• It can remove toxins, harmful amyloid-beta plaques and reduce the risk of Parkinsonism and Alzheimer’s disease.

• As already mentioned, it can reduce mitochondrial damage and neuronal cell death.

• Reduces neuronal stress by easing the Endoplasmic reticulum (ER) of the cells.

Eye health

5. TUDCA and eye health: Studies have shown that TUDCA can prevent retinal damage and help in restoring vision by protecting from photoreceptor degeneration and diabetic retinopathy.

TUDCA acts as a powerful neuroprotective agent on photoreceptors and retinal ganglion cells, which helps in visual processing. Loss of photoreceptors and retinal ganglion cells (RGCs) can slowly lead to visual dysfunction and visual loss. So, TUDCA have the potential to protect the photoreceptors and RGCs. Therefore, it can prevent the risk of many retinal disorders.

6. TUDCA food sources: TUDCA is naturally produced in small quantities in the liver. Actually, the liver produces bile salts and releases them in the intestines. In the gut, the good bacteria metabolise them into UDCA (ursodeoxycholic acid). They are released back to the liver, where they combine with taurine and become TUDCA. So, there is no direct food source of TUDCA. But there are food sources which can help the body to produce TUDCA. Some food sources are :

• Taurine-rich: Non-vegetarian foods like poultry, fish like salmon, tuna, and shellfish.

• Bile stimulators like beets, artichokes, ginger, turmeric, greens like arugula, dandelion, coffee, and citrus.

• Probiotics like fermented foods (Kimchi, kefir, yoghurt).

• Fibres like flaxseeds, chia seeds, oats.

Supplements

7. TUDCA supplement: Dietary supplements are water-soluble bile derivatives; synthetic TUDCA are used as a supplement. Commercial TUDCA are paired with Milk Thistle, which can have a dual action of liver-protective and regenerative support. The recommended dosage is 250 -1000mg/day. There are no severe side effects, but a high amount can cause diarrhoea or stomach upset. Commercially available in the form of pills, capsules and powdered form. Contraindications are for individuals with gallbladder disease, pregnant or lactating mothers and those taking diabetic drugs and insulin.

8. TUDCA and NAC: Another pairing of compounds as a supplement has been popular, such as TUDCA with NAC (N-Acetyl-L-Cysteine), which is a precursor of glutathione, an amino acid which is a potent antioxidant. Both compounds, as a pair, act as a powerful agent for free radical damage, oxidative stress, and the detoxification of cells from harmful toxins. It helps in the clearing of toxins, especially from the liver and kidneys. This combination also enhances the metabolism of dietary fat by improving the bioavailability of bile acids.

Bile salts

9. TUDCA supplement usage: TUDCA supplement is generally recommended by health care professionals mainly for liver health support, metabolic support and neurological health support for brain and eye health. Ideally, TUDCA supplement should be taken post-lunch or dinner, after a large, proper meal so that it can facilitate the smooth flow of bile salts and help in absorption. Start with a lower dose, then gradually increase the dose so that the tolerance level is assessed. Drink a full glass of water along with the dose, as it can be absorbed more smoothly. The standard dose limit should not be exceeded to prevent side effects.

10. Takeaway: TUDCA is a naturally occurring bile acid which has some amazing health benefits apart from supporting liver health. Studies have shown that it has antioxidant properties, such as reducing cellular stress, promoting cellular repair and regeneration, protecting brain and eye health, and supporting metabolic health by improving insulin sensitivity and glucose metabolism. Dietary sources and supplements are taken to increase the bioavailability and optimise the functions. It can also help to treat liver cholestatic diseases.

Thanks for reading.

Peace and love 🙏

Enzymes: 6 amazing facts 🙌

by drjurisharma, posted in Food, life, nature

Hello everyone ! Have a wonderful and safe day. 🙋🏻

Enzymes are an integral part of the body’s metabolism, growth and repair. They are crucial for gut health, the ageing process and maintaining overall good health.

Six facts about the fantastic enzymes :

1.Enzymes are protein or protein-like substances found in our body which acts as a catalyst at a cellular level and speed up the biochemical process of energy production, growth and repair of tissues.


2.Enzymes are specific and are very selective to which substance they bind to and activate the process of breakdown and digestion. Whatever food, we consume, each of the food types stimulate a different set of enzymes.
Carbohydrate stimulates enzyme Carbohydrase like Amylase. The enzyme lactase digests lactose. People who lack lactase suffers from lactose intolerance.
Protein stimulates enzyme Protease like Pepsin, trypsin.
Lipid stimulates enzyme Lipase which digests fat by emulsification.
Some more examples of enzymes are: ATP synthase helps to convert ADP to ATP. Helicase unzips DNA strands.

3. Enzymes are sensitive to temperature and ph change. A slight temperature change can either slow down or speed up the enzyme activity. Large temperature changes can denature and can even lose their function. Similarly, ph changes can directly influence enzyme activity.

4. Enzymes stores in our body can be depleted slowly due to causes like ageing, unhealthy food habits like overprocessing, refined food consumption. Overcooking of food can cause the breakdown of natural enzymes present in the food. Therefore, enzyme deficiency in the body can lead to digestive issues like bloating, gas, food intolerance, anaemia, lethargy and heartburn.

5. There have been multiple enzyme supplements available and marketed commercially with different benefits in the market. But it is essential to know that not enough studies/researches are done to prove either their efficacy or side effects. So, before using the supplements, it is crucial to inform your Physician or else, it may have a drug interaction with your regular medicines currently taken.

6. Certain food rich with natural enzymes which can be consumed but in moderation:
Pineapple has bromolein, and Papaya has papain, and they both are protein enzymes. Avocado has Lipase, and bananas have amylase and maltase. Natural raw honey, wild sprouts (alfa, alfa) and kefir are also rich in digestive enzymes. Fermented food like saurkraut, kimchi is rich in digestive enzymes and even probiotics.

Thanks for reading.

Blessings and much love to all 💐

 

Gut Health 🙌

by drjurisharma, posted in life

Hello everyone ! Have a wonderful and safe day 🙋🏻

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Why is gut health so relevant these days ? Because, in the majority of the diseases, researches have shown that the underlying cause is due to an unhealthy gut.

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Most of us are not aware of the fact that within the twist and turn of the internal coils, that is the intestines, there is often a war between the good and bad bacteria. This struggle results in gut imbalance and thereby cause several health issues like autoimmune diseases, hormonal imbalances, mental health issues, metabolic diseases and even skin problems like acne, depigmentation and psoriasis.

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As we must have already known, the digestive tract carries millions of colonies of bacteria. The right bacterial flora within the coiling of the intestines is bestowed upon many functions to perform to maintain a healthy body. They are responsible for breaking down food into energy, eliminate waste and toxins, and most important is to support the immune system. So, our gut health is under immense pressure to perform well.

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The gut, when encountered with a burst of harmful bacteria from any food sources, there is a war between the good and the harmful bacteria, and a sudden state of imbalance arises. Therefore, this gut imbalance may lead to different health issues, as mentioned above.

Common symptoms and diseases of improper functioning of the gut are:

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1. Slowing of metabolism: This may result in decreased energy production, less absorption of nutrients and deposition of toxins in the different parts of the body. So, there is a lack of energy, tiredness and fatiguability. We may suffer from vitamin and mineral deficiencies as absorption of nutrients is poor.

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2. Digestive issues like gas bloating, diarrhoea as the good bacteria are continuously struggling to restore the balance. Irritable bowel syndrome, acid reflux, colitis are some symptoms of invasion of harmful bacteria.

Man having problems/ insomnia, laying in bed

3. Mental health issues like depression, anxiety, mood fluctuation may occur. As toxins get deposited in different parts of the body due to the harmful bacteria, they may interfere with the production of happy hormones like serotonin and other neurotransmitters that can elevate the mood.
4.Lack of sleep: The gut imbalance causes hormonal imbalance, and the serotonin cycle, which regulates the sleep cycle gets wholly disrupted. So, the person with gut issues may suffer from sleep disturbances.

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5. Autoimmune diseases like Lupus, Crohn’s diseases, rheumatoid arthritis appear where the underlying issue can be an unhealthy gut.
6.Skin issues: When gut inflammation start spreading to other areas of the body, including the skin, there are issues of acne, eczema, psoriasis, complexion disorders, especially on the face.
7. Metabolic problems like diabetes type 2, stubborn weight gain, and obesity are common with gut issues.

Some useful ways to keep a healthy gut:

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1. Eating less or no sugar at all as the sugar becomes the medium of growth of harmful bacteria.
2. Drinking lots of water dramatically helps to eliminate the toxins and also facilitate the digestive process.
3. Chewing food with each bite, about 30- 50 times. Though it may sound tedious, this mastication process may help the food to digest and absorb the nutrients properly.
4. Consuming more fibrous food help to form the stool bulk and help eliminate waste and toxins.

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5. Mono meals as preparing a single meal with combining many food ingredients which allows the body to digest food better.

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6. Consuming fermented food (pickled vegetables) and probiotics help to flourish and restore the good bacterial flora.

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7. Effective foods are bone broth (contain collagen which cleanses the gut), ginger, blueberries, peppermint oil, healthy fats like omega-three fatty acids, all benefit the gut.

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8. Low impact exercises: Low intensity exercises like rebounding, stretching, walking, yoga and low impact cardiac workout can be helpful for gut health.

Thanks for reading.

Blessings and much love 💐

Post: 7 tremendous benefits of a particular breathing technique (Kapalabhati)

by drjurisharma, posted in healing, health, wellness

I have been a yoga practitioner for years. It has been very instrumental in overall wellbeing in my life.
Kapalabhati in Sanskrit means ‘skull cleaning or shining’. It is a breathing technique practised as Pranayama in yoga. Though the word sounds awkward, it is a breathing exercise of successive, rapid, forceful exhalations followed by brief passive inhalation.

The procedure is quite simple:

  • Sit comfortably in Padmasana or simply legs crossed.
  • Rest your hands on your knees.
  • Follow your normal breathing for some time.
  • In a quick moment, contract your abdominal muscles, and forcefully exhale air from both of your lungs.
  • Then allow air to fill your lungs slowly without effort.
  • Perform this cycle for 10 times at a stretch, then return to normal breathing. With daily practice, the cycle can easily go up to 120 times with each round.

Since this is an ancient old practise, in spite of having tremendous benefits, it has some contraindications.

  • Not to be practiced by women who are either pregnant or during menstrual cycle.
  • As there is too much of abdominal movements, not to be practiced by someone having abdominal hernia.
  • Not to be practiced by a person with slip disc, back pain or neck injury.
  • If you suffer from acute respiratory infections, it is better to rest, and let the infections go before doing any Pranayamas.

This practice has ample benefits. 7 important ones are.
1.It is a very useful tool to release congestion and volatile toxins from the body. It also cleans the nasal passage and respiratory system. It is powerful detoxifying method.

2.Since there is a contraction, relaxation of abdominal muscles, it stimulates and improves digestion.
3. It increases heart rate and blood circulation.
4. It is known to reduce stress, anxiety and tensions.

5.The endocrine system and glands are stimulated and regulated.
6.Since you focus entirely on your breathe, your mind gets rid of unnecessary thoughts, hence helps in concentrating. Therefore, a useful tool during the examination.
7. This breathing technique helps to treat diseases related to the nervous system, endocrine system and mental health.

Post : 7 perks of having fibre food.

by drjurisharma, posted in healing, health, wellness

Fibre foods are plant extract foods which are either soluble or insoluble fibres. Fibres are found in the outer layer of whole grains and plants which remain undigested in the gut. They cannot be digested by our body’s digestive enzymes. As they remain undigested, they facilitate the digestion process, help in digesting other food in the gut and also modulate the consistency of body waste. Dietary fibre foods are whole wheat, rice, oats, corn, fruits, veggies, pulses and nuts.

Now, the 7 perks of fibre food that I would like to convey are…

  1. Fibre food are ideal for weight management reason. This type of food gives the sensation of fullness after consumption and provide the bulk of body waste which helps to clean the bowel. Therefore, it helps to maintain the body weight. 
  2. As fibre food takes longer chewing time, longer digestive time, so glucose formation in body is slow, insulin response is slower too. The person tend to eat less and does not feel hungry for a long time. As a result, slowly loses the excessive weight. Therefore, these food are highly recommeded for weight loss.

3. Fibre food helps in reducing blood sugar level. Since fibre content is not digested hence it is not added to the blood sugar level. Clinically, fibre food have found to reduce postprandial glycaemia and increase insulin sensitivity. So, they are good for diabetics.

4.Since this food maintain the blood sugar level and gives the sensation of fullness, They are clinically recommended for gastrointestinal disorders and obesity.

5. Plant extracts food are rich in fibres, antioxidants, vitamins and minerals. Hence, they have the added benefits of removing toxins along with body waste and help boost the body’s immunity.

6. Studies have proved that fibre food helps in lowering blood cholesterol level so help in reducing risk of hypertension, stroke and coronary artery diseases.

7. Fibre food facilitate the digestive process, helps in removing unwanted waste, toxins, helps in cleaning the bowel. Therefore, fibre food intake helps in reducing the risk of bowel cancers.