Tag: depression

10 facts : What is SIBO or blind loop syndrome ?

by drjurisharma, posted in Aging,elderly, discomfort, disease, Blog, healing, health, SIBO, intestinal disease, IBS, diabetes, abdominal pain, bloating,gas, pain,, Supplement, Vitamin Deficiency, mental health,, wellness

1. SIBO, abbreviated as small intestinal bacterial overgrowth, is a condition where there is an overgrowth of bacteria that are not supposed to be present in the normal scenario in that part of the digestive tract. This occurs particularly following a disease or abdominal surgery, when the passage of food and waste becomes slower, creating a breeding ground for bacterial overgrowth.

2. When the wrong types of bacteria overgrow in the small intestine, they feed on the nutrients and food for the otherwise beneficial bacteria, which can lead to abnormal symptoms in gut health. These wrong types of bacteria can feed on the protein and vitamin B12, bile salts which are supposed to support the digestion of fats. In normal circumstances, the small intestinal bacteria digest the carbohydrate and convert it to short-chain fatty acids and gas. Therefore, when there is overgrowth of bacteria, more gas and toxins are produced in the gut leading to many GI symptoms and malnutrition in the long run.

3.The prevalence of SIBO is about 80-90% in cases of irritable bowel disorder, intestinal dysmotility , pancreatitis and chronic systemic conditions. It is more prevalent in the elderly and female population. Usually, the incidence increases with age and the presence of chronic intestinal disorders and dysmotility. SIBO is considered by clinicians as a differential diagnosis of other gastrointestinal non-specific disorders as the actual aetiology is still unknown.

4. The GI symptoms following SIBO are many:

• Gas, bloating, nausea

• Abdominal pain, distention

• Constipation

• Indigestion

• Weight loss, fatigue

• Watery or mucus in poop.

• Hard or lumpy poop.

5.Unexpected and systemic signs may appear due to excess toxins released in bloodstream

(endotoxemia) in SIBO:

• Food intolerence

• Fatty liver

• Fibromyalgia

• Irritable bowel syndrome

• Anxiety, depression, suicidal thoughts

• Endometriasis

• Disruption of mentrual cycle.

• Prostate diseases.

• Atrial fibrillation

• Siezure

6.Though the actual cause of SIBO is unknown, hence, there are several underlying conditions which can be the risk factors:

• Ageing: As age progresses, there may be changes in microflora, degeneration of acid-producing gastric cells, intestinal dysmotility which may lead to bacterial overgrowth.

• Irritable bowel syndrome leads to dysmotility, delayed transition of food, wastage.

• Chonic metabolic diseases like uncontrolled diabetes,

• Celiac disease,

• Lupus,

• Scleroderma,

• Pancreatitis,

• Chronic kidney diseases

• Fatty liver,

• Structural problems in the intestine due to gastric surgery, partial blockage, antibiotics or narcotic drugs overuse.

7. Several complications of SIBO can eventually worsen gut health if left untreated:

• Inadequate digestion and absorption of fat, protein, carbohydrate: Since, overgrowth of bacteria in the small intestine damages the bile salts so the fat remains undigested. The mucous lining of the intestines is damaged too by the excess bacteria causing poor absorption of carbohydrate, fat and protein. Therefore, there is malnutrition, diarrhoea, and weight loss.

• Vitamin B12 deficiency: As the fat remains undigested, the fat-soluble vitamins A, D, E, and K remain unabsorbed. Vitamin B12 which is synthesised in the small intestine is completely affected So, the individual may suffer from vitamin B12 deficiency. Therefore, due to B12 deficiency, nervous system functioning is affected, and blood cell production is lowered. There can be irreversible damage to the nervous system in the long run.

• Calcium absorption: Bacterial overgrowth damages the intestine slowly, resulting in poor absorption of calcium thereby affecting bone health. Weakened bones, prone to fractures, and osteoporosis are common. Kidney stones are also common in cases of poor calcium absorption.

8.There are no standard diagnostic tests for SIBO. The clinical symptoms of SIBO can be nonspecific. Usually, a carbohydrate breath test is considered which is inexpensive and non-invasive. A bacterial culture of jejunal aspirate of more than 1000 units/ml can support the diagnosis. Upper endoscopy is invasive but is done in patients to further support the diagnosis. Laboratory findings like vitamin levels, malnutrition markers are considered to support the diagnosis. Only, in rare cases is, biopsy of the small intestine done. Imaging tests like CT, MRI are done to rule out intestinal abnormalities.

9.Since the condition of SIBO is complex and can be involved with multiple underlying conditions, it is very difficult to manage and treat such cases. The treatment is mainly symptomatic like changing diet, lifestyle, and antibiotics to reduce the bacterial colonies. The recurrence of SIBO is also common so repeated courses of antibiotics are necessary. Supplementation of vitamins in certain cases is required. Surgery is only necessary in case of small intestinal abnormality, diverticula, bowel obstruction, or Crohn’s disease.

10.Again there is no standard diet for every individual who suffers from SIBO. It is individual-specific depending on symptoms and underlying conditions. The goal of diet change is to assist in the treatment and lower the symptoms. The diet should be low in carbohydrates, low in fat, and moderate to low in fibre. Processed sugar items, dairy, whole grains, deep-fried items, and raw vegetables should be avoided. Generally, probiotic-rich food, meat or fish, rice, cooked vegetables, plenty of fluid/water/soups and vitamin supplementation are recommended by the experts.

Thanks for reading.

Peace and love 🙏

Dealing with emotional thoughts: A perspective 🙌

by drjurisharma, posted in Anger, frustration, pain, jealousy, hatred, fear, greed, lust,, Emotional thinking, thoughts, feelings,fears, pain, anxiety, hurting, Emotional thoughts, fear, pain, emotions, healing, health, life, Mind, thinking,overthinking,wondering mind, Science, self healing, wellness

Emotions are subjective yet universal among all humans. They significantly influence our daily lives, decision-making, behavior, relationships, psychological states, and physical health.

Our emotional thoughts arise from emotional reasoning in response to situations, people around us, events, and past experiences. Emotional responses trigger our thoughts, feelings, actions and behaviors in reaction to external events, situations, or circumstances. Thus, emotions play a crucial role in our everyday lives and the decisions, we make.

Research states that all things in the Universe are made of energy which has a vibrational frequency. Emotions too, have amplitude and frequencies. Positive emotions like peace, love, and joy are found to have higher frequencies as compared to negative emotions like anger, fear, guilt, and sadness. According to the frequency chart, emotions like guilt, and shame have as low a frequency of 30-20 Hz to emotions like love, peace have as high as 500-600 Hz. Studies often link low frequency to disease state, depression and stress. Negative thoughts and feelings can often create a low vibrational frequency state which can create anxiety, and stress and affect our physical health.

Studies have consistently shown that negative emotional thoughts and feelings can significantly affect our physical health and overall well-being. The importance of the mind-body connection and the gut-brain connection highlights how our physical body responds to our thoughts, feelings, and mental state.

While unwanted changes, negative experiences, and challenging situations are a part of life, learning to manage our emotional state and well-being is a significant challenge—but it is certainly not impossible. Events such as:

Death of a loved one

Suffering from an illness

Getting laid off from a job

Divorced

Getting married, having a baby

Financial issues

Dealing with a pandemic or war-like situations

Cheating partners

Domestic violence

Physical health often suffers when emotional health is struggling. During times of emotional crisis, many individuals may seek an escape through unhealthy coping mechanisms such as alcohol abuse, drug abuse, or binge eating, attempting to suppress their emotional turmoil. Unfortunately, this approach does not lead to healing and can result in disastrous consequences. The list of physical impacts and symptoms experienced in a state of emotional stress is extensive.

Physical symtoms frequently seen as:

Palpitation

Chest pain

Back pain, neck stiffness

Fatigue , tiredness

Poor sleep, insomnia

High blood pressure

weight loss / obesity

Stomach upset like bloating, acidity

Physical signs of our mental state can often be quite apparent. Additionally, there are mental symptoms that we or those around us may observe, even if we attempt to deny them. Here are several such signs:

*Resisting to acknowledge the thoughts instead of accepting

*Not self-realising and accepting the present situation

*Trying to control the situation or the people around

*Suppressing emotional thoughts and feelings instead of expressing

*Living in blame

*Focussing on lacks

*Forgetting gratitude

Dealing with emotional thoughts is not easy. It’s important to remember that while I cannot control external events or situations, I can influence my own mental state to cope and adapt positively. Here are five simple tools that can help bring about a positive shift in the mental state:

1.Self-Responsibility: Recognizing and taking responsibility for our mental state is crucial. Often, we create more pain and hurt from emotional thoughts and feelings by overthinking and getting caught in repetitive loops, rather than addressing the actual situation. It’s important to remember that 95 to 98 percent of our worries are self-created rather than based on reality. Only about 2 to 3 percent of our concerns are truly justified. Therefore, it’s essential to become aware of and take responsibility for our mental state, as this is the first step towards creating positive change.

2. Let go of control: We have to understand that we cannot control everything that happens in our lives. We have to let go and trust the Divine and timings of life. Letting go is important to heal and restore balance.

3.Journaling and practicing gratitude: Daily journaling can release deep thoughts that might otherwise feel heavy and hurtful. Practicing gratitude and maintaining a thankful mindset can elevate our vibrational frequency and promote healing.

4. Healing the Sacral Plexus Chakra: According to Yogic science, the sacral chakra is responsible for maintaining emotional balance, creativity, and a sense of vitality. To heal this chakra, engaging in yoga and physical activities such as dancing, swimming, and savoring life’s simple pleasures— like playing with a child, listening to birds chirping, or enjoying the sound of flowing water—can help release blockages.

5. Daily Affirmations: Choosing words and phrases that align with your life goals, such as mantras or sacred verses, can significantly enhance your positivity and resilience. Reciting these affirmations each morning can set a positive tone for the day. Some powerful examples include: “I trust the Universe,” “I am strong and powerful,” and “I let go” “My food nourishes my body and mind”.

Every day, we experience a wide range of emotions based on external events, past memories, current situations, and various circumstances. It is essential for us to recognize our emotional limitations and boundaries in order to protect our mental well-being. One of the most important things we can do is to let go and trust the Supreme, the Divine, as not everything is within our control.

Self-reflection is crucial for restoring our emotional balance. Engaging in daily activities such as meditation, yoga, chanting, and appreciating the small joys in life holds great significance in achieving mental equilibrium. Finally, staying grateful and expressing our thankfulness for this journey of life is truly fulfilling.

Thanks for reading.

Peace and love 🙏

8 facts: Broken Heart Syndrome 💔

by drjurisharma, posted in Broken heart syndrome, Tokotsubo syndrome, emotional health, fear, pain, emotions, healing, health, Heart disease, Heart, cardiovascular disease, cardiomyopathy, Science, wellness

1.Broken heart Syndrome is a temporary heart condition known as Takotsubo cardiomyopathy, as it was first described in Japan in 1990. This condition of the heart weakens the left ventricular muscles, making blood pumping difficult. The condition is associated with a severe emotional episode, extreme physical stress, loss of a loved one, sudden illness, or a serious accident.

2.Broken heart syndrome symptoms may mimic the classic symptoms of a heart attack like pain in the chest, severe pressure or heaviness in the chest, shortness of breath, fatigue and cold sweats. Pathologically, there is no actual blockage in the coronary arteries. Research shows that extreme emotional, and traumatic stress, the rise of catecholamines and stress hormones like adrenaline causes the heart muscles or the coronary arteries to stun the heart temporarily, preventing the left ventricle from pumping blood effectively.

Ballooning of left ventricle

3. Studies show about 90% of the cases are women and many of them recover without any long-term damage. The exact cause is still not known. But the common causes which are found to be:

• Sudden loss of a loved one.

• Severe physical pain.

• Sudden illness.

• Domestic violence.

• Serious accident.

• Huge financial loss.

• Intense fear.

4. Though physical symptoms and ECG changes like ST segment elevation can misdiagnose a heart attack, other imaging studies are required to rule out a heart attack. The most common diagnosis of Broken heart syndrome is no evidence of blockages in coronary arteries which on the other hand, is a classical sign of a heart attack. In the echocardiogram, there is a bulging of the lower part of the left ventricle seen in Broken heart syndrome, which resembles a tako-tsubo (a Japanese octopus trap pot), hence the name is derived. This is quite a confirmatory sign of Broken heart syndrome or Takotsubo cardiomyopathy.

5. To sum up the differences between Broken heart syndrome and heart attack are:

• The angiogram shows no signs of blockage of coronary arteries.

• Blood work, especially enzyme levels shows no sign of heart damage.

• An echocardiogram shows abnormal bulging or ballooning of the lower part of the left venticle so, also known as Balloning heart syndrome.

• Recovery is faster within days to a couple of weeks.

6. Broken heart syndrome is not usually fatal, and under treatment and observation, the individual recovers within weeks to a month. The prognosis is good and there is also less risk of such episodes in future. But in rare cases, it may become fatal causing severe short-term heart muscle failure. Research continues to learn more about the diagnosis and treatment of cases of Broken heart syndrome.

7. There is no standard treatment for Broken heart syndrome and is mainly individual-specific. Medication is required to reduce the stress on the heart muscles. Medications like Angiotensin-converting enzyme inhibitors (ACE), Beta-blockers, diuretics, and blood thinners are used to heal the heart muscles and prevent further episodes. Complete recovery is likely within a month or so.In addition to this, management of stress is also required to prevent such episodes in future.Regular follow-ups are required for the individual.

8. Broken heart syndrome or Takotsubo syndrome has been researched to have certain general pre-disposing risk factors like smoking, hypertension, obesity, diabetes, pulmonary diseases, malignancies, neurological diseases and psychological disorders. Evidence also shows higher prevalences in females compared to males. Although routine checkups, ECG, blood work and echocardiograms are necessary at regular intervals, it is important to work on stress factors like meditation, yoga, deep breathing and mindfulness techniques.

Thanks for reading.

Peace and love 🙏

10 facts to know about Vitamin D linking to mental health🧠

by drjurisharma, posted in cognitive health, fear, pain, emotions, Food, healing, health, life, mental health, Vitamin Deficiency, mental health,, wellness

Vitamin D deficiency is critical for both physical and mental health. Here are some facts to understand the impact of vitamin D on mental health.

1.Several research studies have concluded that low vitamin D levels are directly linked to anxiety, mood changes, depression and cognitive dysfunction such as impaired memory, sadness, weight loss and loss of appetite. Studies have not shown that vitamin D deficiency causes depression but people who suffer from depression do show low levels of vitamin D.

2. Vitamin D mainly maintains the body’s calcium homeostasis. It is also crucial as a neurosteroid hormone and plays a significant role in maintaining normal brain functions and helping in brain development. Therefore, numerous studies have shown that hypovitaminosis D is linked to depression and neurocognitive disorders.

3.Some studies have shown that seasonal affective disorder (SAD) is more prevalent in winter as there is a lowering of Vitamin D levels in the cold season. Lack of exposure to sunlight in winter months is shown to increase the incidences of depression, mood changes and anxiety issues.

4. Rising cases of suicide have been a common risk factor for low vitamin D levels (psychiatric times.com).A research study in 2023 found a correlation between low vitamin D levels with cases of suicidal behaviour. Therefore, vitamin D supplementation is mandatory for all those who have low levels can help to address mental health issues and prevent cases of suicide thereby saving lives.

5.As mentioned earlier, Vitamin D is required for normal brain development. Vitamin D supplementation is essential in childhood for overall brain and cognitive development. Low levels of vitamin D have been found in many cases of ADHD (attention deficit hyperactive disorder). Improved levels of vitamin D by supplementation have shown marked improvement in symptoms of ADHD children.

6. Vitamin D deficiency has been found to have a direct correlation with adult schizophrenia. Studies show that it is quite common to have in individuals with poor nutrition, elderly persons, people living in regions with insufficient sunlight, or during pregnancy. So, it is important to routinely check the levels of Vitamin D to reduce such risk factors. Correction of the levels of vitamin D shows marked improvements in symptoms of such mental illness.

7. Vitamin D acts as a neuroprotective neurotransmitter and helps to maintain the functions of neurons and glial cells of the central nervous system. So, administrating Vitamin D helps to reduce the oxidative stress and neurotoxicity on the cortical neurons. Therefore, controlling the neuronal inflammations helps to reduce many psychiatric illnesses.

8.Strong evidence shows that low levels of Vitamin D are related to neurodegenerative diseases like Alzheimer’s disease, dementia, and Parkinson’s disease. Vitamin D supplementation can improve or even prevent the neurodegenerative process by reducing the deposition of beta-amyloid plaques, intra-neuronal tangles of tau-protein and loss of cholinergic neurons and synapses.

9. Vitamin D levels ranging from 50nmol/L or above are sufficient to maintain overall physical and mental health well-being. Blood levels below 20 ng/mL are treated as insufficient and require immediate vitamin D administration. Normal levels can be maintained by exposure to sunlight, vitamin D supplementation and food sources like oily fishes, eggs, meat, liver, veggies like broccoli, pumpkin, green leafy veggies, green peas, avocados and many more.

10. Though vitamin D is not the only cause of mental health issues, essentially, it is an important nutrient to maintain normal brain function and neurochemistry. In the general population, many people do suffer from vitamin D deficiency, unknowingly. Supplementation of vitamin D can improve the blood levels in individuals and can at least help address the challenges of mental health issues.

Thanks for reading.

Peace and love 🙏

8 facts: Burning mouth syndrome or Glossodynia 👅

by drjurisharma, posted in Adult over 50, Blog, Burning mouth syndrome, BMS, Females, perimenopause, menopause, healing, health, Hot beverages, life, Mouth, tongue,lips, wellness

1.Glossodynia, also known as Burning Mouth Syndrome (BMS), is a fairly common condition. It’s an intermittent burning sensation in the mouth, especially in the tongue, lips, or other areas of the mouth, that is not accompanied by a specific reason. It feels as though the tongue is injured by a very hot liquid. The syndrome may be gradual or sudden in onset. There is no observable physical sign seen either in the tongue or in the mouth while having an episode. The specific cause of BMS is difficult to determine.

2. Most causes of burning mouth syndrome are unknown or idiopathic. Research suggests that it can be related to nerves which carry sensations of taste and pain. The causes are broadly divided into primary and secondary. Primary burning mouth syndrome is uncommon and mainly idiopathic.

3, Secondary burning mouth syndrome is quite common and causes can be related to :

* Vitamin deficiency like Vitamin B complex, lack of iron, zinc ,folate.

* Oral infections like oral thrush, oral lichen planus.

* Allergies following food additives, flavouring substances, mouth care products.

* Acidic drinks, extreme hot liquids, irritating foods like highly spiced foods.

* Dental materials, ill-fitted dentures.

* Dry mouth due to some medicines like anti hypertensives, anti cancer treatments.

* Reflux or Gastro esophageal reflux.

* Endocrine issues like diabetes, hypothyroidism.

* Anxiety, stress, depression.

Hot spicy food

4. Burning mouth syndrome, (BMS) can occur in any individual irrespective of age and gender. But the common risk factors are seen mostly:

* Females.

* More common over the age of 50.

* Post menopausal or perimenopausal women leading to low estrogen levels affecting taste buds.

* Smoking.

5. When a person experience BMS, there is no visible symptoms like discolouration of tongue or bumps. The symptoms found are :

* Altered taste, or metallic taste or loss of taste.

* Tongue and mouth feels like scalding, burning or tingling.

* Dryness of tongue, lips, gums.

* Numbness in the mouth.

Sipping cold water

6. BMS treatment and diagnosis are individual specific depending upon the symptoms. Diagnosis can be done by a saliva or oral swab tests. As far as treatment are concerned, there is no approved drugs. Remedies are there to ease the symptoms like :

* Mild mouth rinses.

* Saliva substitue like Biotene.

* Getting enough vitamin B complex, iron and folate.

* Pain relievers if necessary.

* Sipping cold water or ice chips.

* Sugar free gums chewing to encourage saliva production.

Hot beverages

7. Though it is not always possible to prevent BMS. But,if we are prone to BMS or have been affected in the past, it is important to avoids certain things :

* Very hot liquids, hot bevereges or drinks like highly acidic ones.

* Hot or spicy food.

* Alcohol

* Mouthwash containing alcohol.

* Smoking.

8.Feeling fire, irritations, and a burning sensation in the mouth, you can be sure to have Burning Mouth Syndrome, which is frustrating and irritating. But, once you have acquired it, it takes a while to go away. You can take the above-mentioned remedies and precautions till it heals. But, if there are flare-ups or hasn’t gone for long, you should surely visit your Physician or Dentist.

Thanks for reading.

Peace and love 🙏

10 compelling reasons to consume Flavanoids to combat oxidative stress 🙌

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, detoxification, vegetable,, emotional health, Flavonoids, antioxidants, anti inflammatory, Food, Fresh, local, produce, Fruits, veggies, berries, healing, health, life, meditation, inflammation, disease, physical health, mental health, wellbeing, nature, self healing, wellness
  1. Flavonoids are naturally occurring polyphenolic compounds in various deep-coloured fruits and vegetables. There are 6 different varieties of flavonoids, all of which have antioxidant properties and can help the human body to get rid of different toxins and stress. Therefore, including flavonoids in your routine diet can help to get rid of many chronic health conditions.
  2. Dietary Flavonoids are of 6 subtypes :
    Flavanols , Flavones, Flavan-3-ols, Flavanones, Isoflavones, Anthocyanins.
    Coloured fruits, vegetables, and plants are all rich in flavonoids. Naturally, they are found in apples,purple and red grapes, berries, peaches, oranges, cocoa, chocolate, green tea, black tea, chamomile tea, vegetables like broccoli, lettuce, tomatoes, scallions, red peppers and onions. Flavonoids are dark-coloured pigments so they act as natural pesticides and protect the plants from harmful UV rays, bacteria, viruses and harmful insects.

3. Main functions of flavonoids:
•Powerful antioxidants
•Fights inflammation
•Free radical damage and prevent oxidative stress.

•Anti-haemorrhagic and vasodilatory effects.
•Certain flavonoids, due to their anti-inflammatory and antioxidant properties prevent cancer cells from multiplying and decrease the risk of some cancers.

4.Research shows that oxidative stress can lead to cellular damage and disease development. So, oxidative stress can cause many disease conditions like cancers, diabetes, cardiovascular diseases like hypertension, atherosclerosis, chronic inflammatory diseases, and neurodegenerative diseases. Flavonoids play an important role in reducing this oxidative stress and free radical damage, thereby preventing cellular damage.

Cocoa (Dark Chocolate)

5.Numerous studies have shown that cancers develop due to oxidative stress, genetic mutations,hypoxia and reduced apoptotic function. Apoptosis, in simple terms, is a normal cellular activity whereby the body tries to eliminate unwanted cells. Flavonoids play an integral part in promoting apoptotic cellular pathways and preventing cancer cells from proliferating and multiplying.

6.Research shows that flavonoids protect the different organs including the liver and brain from free radical damage. Studies show that flavonoids have protective effects of various liver injuries caused by drug and alcohol usage. Since, they are anti-inflammatory, and antitumor, they protect the hepatocytes from inflammation and fibrosis.

7.Flavonoids are a polyphenol group of compounds that can improve and reduce the symptoms of depression and anxiety. Clinical studies in the past have shown that dietary intake of flavonoids can lower the risk of depression. However, further studies are still anticipated to make substantial proof.

8.Flavonoids are best when naturally consumed as all dark-coloured fruits, vegetables, and green tea contain abundant polyphenolic compounds. It should be included in the routine diet for overall
well-being. However, many flavonoid supplements are out in the market. The best supplements are Cucurmin (Tumeric), Green tea, grape seed extract, Resveratrol, Quercetin, hesperidin and Rutin.

9. Toxicity: Intake of natural flavonoids on a daily diet is usually enough. Sometimes, flavonoids supplements are clinically recommended. However, the risk of flavanoid toxicity exists, if someone takes a huge amount of highly potent supplements. It may affect anaemic and elderly patients as flavonoids may bind with non-heme iron. Flavanoid toxicity may cause liver failure, hemolytic anaemia and male reproductive issues. Recommended daily dose of consumption should be around 400-600mg/day.

10.A healthy routine diet rich in flavonoids will provide all the necessary support to the human body to maintain biological activity, provide anti-oxidant effects, reduce oxidative stress and prevent chronic diseases, maintain cardiovascular health and prevent infectious diseases. The key point is that the food readily available to us contains the most effective flavonoids and antioxidants that fortify our health and immune system, making expensive supplements unnecessary

Thanks for reading.

Peace and love 🙏

10 facts to know about the MTHFR gene 🙌

by drjurisharma, posted in Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, healing, health, life, MTHFR, gene mutations, genetic mutations,, wellness
  1. MTHFR, Methylenetetrahydrofolate reductase, is an enzyme found in human chromosome 1,located exactly in the short arm. It plays a significant role in folate and homocysteine (amino acid) metabolism. Studies have shown that individuals with MTHFR deficiencies can have hyperhomocysteinemia
    with homocystinuria.
  2. Research in the past decades has shown that this enzyme plays a key role in homocysteine metabolism. The deficiency of this enzyme is an inborn error of folate metabolism, which is quite
    rare. Yet, several studies have identified this variant as the most common cause of
    hyperhomocysteinemia and a risk factor for many disorders connected to defective homocysteine
    metabolism.

3.Genetic deficiency of MTHFR is rare, but around 50 cases have already been identified worldwide. Symptoms in such individuals are seizures, developmental delay, neurological impairment, gait dysfunction, and a very high level of homocysteine in urine and plasma. Genetic testing of the gene mutation can be done on a saliva swab and blood sample.

4.Genetic mutations are inherited and acquired from the parents. There are 2 forms of mutations that can occur on the MTHFR gene – C677T and A1298C. If one such variant is present, one is less likely to have health issues but if both variants are present, then the individual is likely to have serious health problems.

Depression

5.Health issues associated with people who have two variants of the MTHFR gene are :
Homocystinuria
Alopecia areata
Spina bifida
High blood pressure
Depression or bipolar disorder
certain cancers
Miscarriages

Pregnancy

6.MTHFR affects pregnancy: Research has shown a link between MTHFR gene variants related to repeated miscarriages. It is important to test for MTHFR gene mutation in women who have suffered unexplained recurrent miscarriages or delivered babies with neural tube defects. Extra folate supplementation and blood thinning administration can be useful to prevent such miscarriages.

7.Diagnosis of MTHFR variant cases is done by testing blood samples and saliva swabs in individuals with a very high level of homocysteine in urine and plasma and vitamin deficiencies of folate, choline, vitamin B12, B6 and riboflavin. MTHFR mutation variant people may not have health issues and can be treated by preventive measures of supplementation of folate and vitamin B and lifestyle changes like a nutritious balanced diet, sleep, exercise and avoiding smoking.

Down’s syndrome

8.Babies and children born with MTHFR mutation variants may present with symptoms within the first year of birth. Such children may have ADHD (attention deficit hyperactivity disorder), autism, impairment of sleep, mood disorder, hyperhomocysteinemia, vitamin, folate deficiency, pediatric stroke, spina bifida and Down’s syndrome.

9.Having gene variants is common in the human population. This particular MTHFR variant gene is common in some ethnicities like in Hispanic individuals. Hispanic races have commonly the MTHFR C677T variant. People with such variants are able to process all types of folate. Research shows that 400mcg of folic acid daily can raise the blood folate level irrespective of whether you are MTHFR genotype.

10.Folate and vitamin B are naturally found in many food sources which should definitely be part of the daily diet. Legumes, leafy greens, citrus fruits, broccoli, Brussels sprouts, bananas, avocados and nuts are rich in folate and should be consumed regularly to have normal levels of folate and promote healthy cell division irrespective of gene mutations.

Thanks for reading.

Peace and love 🙏

10 facts to know about constipation 👐

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, constipation, bowels, colon, bowel movements, bowel disease, deep fried food, detoxification, vegetable,, emotional health, french fries, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, mental health, milk, dairy, curd, yoghurt, muscle, body, Science, stomach, abdomen, intestines, wellness
  1. According to medical terminology, constipation is when a person has irregular bowel movements, usually less than three times a week. Normally, a person with regular bowel movements has stool elimination three times a day to three times, a week. Constipation has been the most common gastrointestinal issue affecting millions of people daily.
  2. Normally, the food passes through the large intestine, and the water is absorbed in the colon while forming the faecal matter or stool. Then, the stool formed in the colon is pushed down to the rectum by muscle contraction. If the muscle contraction in the colon is prolonged, by the time, stool reaches the rectum, more water is absorbed making the stool too hard to pass. Passage of the dry hard stool becomes very difficult causing constipation.
  3. The most common causes of constipation are: Lack of movement, lack of exercise, stress. Lack of fibre in the diet.
    Not drinking enough fluids.
    Changes in dietary habits, pregnancy, traveling, ageing. Medications.
    Irritable bowel syndrome.
    Anal fissure.

4.Common symptoms of constipation:

Pain abdomen.
Painful bowel movements.
Feels uncomfortable or bloated.
Bowel movement less than 3 times a week.

5.Generally, constipation is relieved by switching the diet to more fibrous food, more intake of fluid, and exercise. However, if the person is not relieved of the symptoms despite these above- mentioned measures and maybe, there is a history of blood in stool, episodes are more frequent, then, it is necessary to seek medical attention.
Diagnosing constipation is based on medical history, a physical examination which covers an anorectal examination, barium enema, and colonoscopy.

6.Constipation is usually treated by diet and lifestyle changes.
Lifestyle changes include regular exercise, more intake of fluids in the daytime, giving enough time for daily bowel movements.
Dietary intake of at least 20-30 grams of fiber daily, including whole grains, fruits like bananas, pineapple, papaya, oranges, apples, kiwis, berries and vegetables, is recommended.
Changing the existing medication if any.
If the above measures don’t work, then laxatives are prescribed.

7.Certain risk factors which may lead to constipation:
*Mental health issues: Due to depression and stress-related issues leading to unhealthy diet, irregular meal timing, anti-depression medication, lack of exercise, and eating disorders.
*Old age causes weakening of the muscle lining so sluggish bowel movements.
*Pregnancy causes the bulky uterus to press against the intestinal wall making it harder to defecate.
*Eating lots of refined food, junk food and not eating enough fibre causes hard stool. *Medications like iron pills, antacids, blood pressure medicines, allergy medicines, anti- depressants.
*Diseases: Stroke, paralysis, Parkinson’s disease, diverticulitis, multiple sclerosis, irritable bowel disease, colon cancer.

8.Constipation commonly occurs in most cases due to dietary changes or lack of physical activity. The condition is resolved usually by changes in diet and lifestyle. But, it can be a warning sign and may require immediate medical attention when:
there is severe cramping pain with sudden onset of constipation.
Blood in stool.
Loss of weight.
Severe pain with bowel movements. Constipation is for a prolonged period.

9.Generally, dietary and lifestyle changes can prevent constipation : Drinking 3-4 glasses of water every day.
Adding vegetables and fruits to your diet every day.
Routine physical activity and exercise is a must.
Eating Probiotics such as curd, yoghurt or kefir daily. Avoiding processed food, processed meat, and fried food. Drinking less alcohol and caffeinated drinks.
Not ignoring the urge to poop.

10.There are several different laxatives available, just for your information.
Osmatic laxatives like milk of magnesia cause softening of stool.
Stimulant laxatives increase the speed of bowel movements to help the stool to move through. Lubricant laxatives like mineral oil lubricate the intestine and help to slide the stool along the colon.
Saline laxatives are used as enemas to empty the bowel.

Thanks for reading.

Peace and love 🙏

Are popcorns 🍿 healthy ? 9 facts 🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, deep fried food, eyes, Food, glutathione, antioxidant, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, popcorn, Science, skin, cancer, anti inflammatory, plant, nature, medicine, herb, stomach, abdomen, intestines, Uncategorized, wellness
  1. Popcorns are corn kernels which get popped when heated. Today, across the world, this has become the most popular snack amongst all age groups. Corn is the oldest grain which has been consumed for over 5000 years. It has been popular due to its easy availability and low cost. As far as health point of view is considered, it is a whole grain food, rich in fibre, low in calories and dense in nutrients.
  2. Studies show that popcorn is high in fibre and contains many vitamins and minerals. Important nutrients in popcorn are vitamins B1, B3, B6, iron, potassium, manganese, zinc, copper and phosphorus. Many studies also show that it is rich in polyphenols which are potent antioxidants. Polyphenols reduce the risk of damage by free radicals, diabetes, and heart disease and improve gut health. Popcorn is gluten-free so it can be a healthy option for people with gut issues.

3.Since, it is high in fibre and low in calories, it can help in weight loss. Eating a cup of popcorn which is around 30 calories can relatively be more beneficial in terms of fibre and nutrient content than any other popular snack. Also, it can give the feeling of fullness and curb your hunger for quite some time. Therefore, eating in moderation of popcorn can be very useful in the process of weight loss in an overweight individual.

4.Popcorn contains antioxidants Zeaxanthin, beta carotene and lutein which are very essential to eye health. These antioxidants can slow the age-related macular degeneration of the eyes, lower the damage caused by blue light and overall improve the eyesight.


5.Other health benefits of yellow popcorn are :
*Boost the metabolism and energy production due to the presence of vitamins B, B3, B6 and folate.
*Popcorn contains niacin which helps to reduce depression naturally.
*Phosphorus, and manganese present in popcorn help to support bone health.
*Popcorn can combat tumour cells due to the presence of ferulic acid.
*It can reduce the level of bad cholesterol and prevent the risk of heart disease.
*It can slow down the process of ageing as it helps in free radical damage.
*It can add iron (28 gm of popcorn containing 0.9mg of iron) to the diet and reduce anaemia. *It can control blood sugar as it has a low glycaemic index and helps in diabetics.

6.Air-popped popcorn is healthiest. Unsalted popcorn, unflavoured is healthier than those with an excess of oil, butter, sugar, caramel, and salt. Microwave popcorn bags which are pre-packed contain the chemical perfluorooctanoic acid (PFOA) and sometimes, trans fat which are harmful to health.


7.Popcorn added to diet in moderation can prove to be safe and beneficial to health. But it may have side effects on certain individuals. Some individuals can have allergic reactions to popcorn like swollen face, and breathing difficulty which may require urgent medical attention. People with digestive diseases and inflammatory bowel disorders can have flaring-up symptoms when consuming popcorn.


8.Popcorn is the ideal choice for adding to your diet in moderation. You can definitely enjoy popcorn daily, as long as you stick to one cup per day without any butter, salt, sugar, or artificial flavors. This will provide a healthy dose of whole fiber content, making it the most nutritious snack option for your diet.

9. Yellow corn which is organically grown, non-GMO, is best for regular consumption. Popcorn which is popped from such type of high-quality corn, air popped with no added flavours is ideal and provides immense health benefits. Rich in phytonutrients, vitamins, and minerals, whole grain fibres can help to reduce the risk of chronic illnesses, obesity, diabetes and many malignancies.

Thanks for reading.

Peace and love 🙏

10 facts to know about stomach bloating 🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, deep fried food, detoxification, vegetable,, Food, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, life, physical therapy, pain, body aches, spinal,, Science, stomach, abdomen, intestines, Uncategorized, wellness
  1. Stomach bloating is usually feeling fullness, swelling or tightness around the abdominal region. The most common thought that comes to mind when you feel bloated is eaten too much, too heavy a meal or your stomach is filled with gas or air. Abdominal bloating is common both in adults, children and also in babies. The common symptoms of bloating can be pain, distention, belching, excessive gas causing flatulence and abdominal gurgles.
  2. Why do we feel bloated? Bloating commonly happens due to excessive gas or air. Sometimes, gas accumulates in the digestive tract due to the slow breaking down of the undigested food due to delayed emptying. This can give rise to bloating. Another common cause is air getting swallowed while eating or drinking too fast which gives the feeling of bloating.
Fizzy drinks

3.Gas is a very common cause of bloating. Drinking fizzy drinks or carbonated beverages causes swallowing of air which may give rise to bloating and disturb digestion causing pain and discomfort. Eating a heavy carbohydrate-rich meal causes difficulty in digesting tougher carbs like sugars such as fructose, lactose, sorbitol or wheat and beans. A considerable quantity of carbs remain undigested causing slow fermentation resulting in gas. The fermentation is caused by gut bacteria while digesting the carbohydrate.

4.Other causes can be constipation, heartburn, malabsorption of food, menstrual symptoms, impaired gut motility, and overgrowth of gut bacteria. There are many medical causes like irritable bowel disorder, parasitic infection, food intolerance, inflammatory bowel disorders like ulcerative colitis and Crohn’s disease, Celiac disease, anorexia or bulimia nervosa, stress, anxiety, depression, hormonal imbalance in case of women.
Some life-threatening causes of abdominal bloating can be ascites in liver diseases, kidney failure, ovarian cancer, and perforation of the GI tract causing the gas to escape giving the symptom of bloating.

5.Bloating is a common symptom in a healthy individual every now and then. Usually, the symptoms of pain, fullness, and discomfort are moderate to severe. It can ease off within hours to 1-2 days normally. Mobility, mild exercise, and having water or herbal teas can slowly ease the symptom. In case of gas, flatulence and constipation, pooping can relieve the symptoms. But, if the condition worsens within days, medical attention is required for evaluation of underlying cause.

6.If the abdominal bloating has a specific cause like food intolerance or food sensitivity, avoiding the particular food or eliminating it from the diet is necessary. Certain food items like sugar food rich in high lactose, and fructose are difficult to digest and can result in intestinal gas and bloating. Food items like wheat, beans, dairy, cauliflower, cabbage, fatty food, fizzy drinks, processed food, beverages can lead to stomach bloating.

7.Bloating is a common problem in many women due to hormonal fluctuations. The female hormone estrogen can cause fluid retention in the body. During phases of estrogen high and progesterone drop, bloating is very common. Moreover, during menstruation, the uterus is already heavy due to fluid can cause stomach bloating. Therefore, in women, during perimenopausal phase and before or during monthly periods, stomach bloating is common. Hormonal birth control pills and oestrogen supplementation can relieve the symptoms with advice from medical experts.

8.Bloating is serious and requires medical attention when the symptoms worsen, continuous pain, bloody stools, fever, and vomiting occurs. Stomach bloating, when associated with physical injury, surgery, ascites in the liver or kidney failure requires medical help immediately. When the abdominal bloating and gas retention becomes chronic, the underlying cause needs to be investigated. As already mentioned before, when hollow organs like the stomach, intestines, gall bladder, uterus, and bladder are distended, they can be palpable and felt on physical examination. Causes like undigested items, fluid, intestinal gas, poop, urine, and internal bleeding in case of injury can be the probable reasons. Inflammation and bacterial overgrowth can also lead to enlargement of the hollow organs. The underlying problem needs to be thoroughly investigated.

9.However, prevention of abdominal bloating can be done if the individual does have this history of bloating quite often. In case of food sensitivity, or food intolerance, avoiding the particular food item is required. Taking long intervals between meals is helpful.
*Having fibres in diet to prevent constipation and easy passage of wastes.
*Drinking water to prevent dehydration,
*Reducing salt intake to prevent water retention,
*Regular exercise and walking.
*Taking probiotic supplements is also quite helpful.
*Some home remedies like apple cider vinegar and applying a warm pad on the stomach may sometimes work too.
*OTC medication like antacids to relieve gas, laxatives to relieve constipation or enema to have bowel motility can be useful too.

Carb rich foods
Beverages

10.Bloating is quite common in a normal individual. If you have an episode of bloating, it is wise to identify and avoid the particular food item that leads to bloating. Normally, avoiding certain situations like having…
*Salty food
*Fizzy drinks,
*Eating too fast should be avoided as it leads to swallowing air.
*Avoiding processed, carb-rich food,
*Fatty food,
*Avoiding alcohol, and smoking as they can create digestive issues .
Having a balanced meal with a bigger portion of fibre in the diet, intervals between meals, drinking plenty of water, and eating slowly can be helpful. Bloating is serious and needs medical attention when the symptom persists, accompanied by other symptoms like bloody stool, weight loss, loss of appetite and persistent pain abdomen. Once the cause is evaluated, treatment can be done accordingly.

Thanks for reading.

Peace and love 🙏