Tag: ageing

10 important facts about tocotrienols 🙌

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, Brain, nervous system, gastrointestinal disease, autism, cancer, Cholesterol, Food, healing, health, Heart disease, Infection,inflammation, Nature,, Palm oil, cooking oil, heart health, cardiovascular disease, Vitamin E, tocotrienols, tocopherol, nutritional, supplements

Tocotrienol complex

1. Vitamin E is actually a complex of 8 different compounds, which include 4 tocopherols and 4 tocotrienols , each of which can be further divided into alpha, beta, gamma, and delta forms. While tocopherols have been the focus of most research, tocotrienols have not received as much attention. Consequently, many vitamin E supplements available in the market predominantly feature tocopherols, leaving the full potential benefits of tocotrienols yet to be explored.

2.Many Vitamin E supplements on the market primarily contain tocopherol as their main ingredient, which means that their full benefits for the body are not realized. Recent research has shown that tocotrienols are powerful antioxidants with various health benefits. They possess neuroprotective properties, help reduce cholesterol levels, promote skin and hair growth, protect the liver, prevent strokes, and may even help prevent sterility. Additionally, tocotrienols are known to combat inflammation.

3.Actually, tocotrienols help significantly in the body to lower inflammation. Studies have shown that tocotrienols are five times more potent than tocopherols in reducing inflammation. Research has shown that tocotrienols are available in different forms: Delta tocotrienols and gamma tocotrienols, of which delta tocotrienols have five times more potency than tocopherols to fight inflammation in the body. In fact, tocotrienols are far more potent than tocopherols in the prevention of oxidative stress.

4. The widespread benefits of tocotrienols can be summed up as :

• Powerful antioxidant.

• Powerful antimicrobial

• Neuro-protective.

• Anti-cholesterol effect.

• Anti-tumour, anti-cancer,

• Prevents stroke

• Anti-inflammatory, prevents autoimmune diseases.

• Protective to the cardiovascular system, hepato-protective, and promotes hair growth.

• Promotes bone health, especially for menopausal women.

Palm fruits

5. Extensive studies have been carried out on the neuroprotective role of tocotrienols, which have shown very positive results on people with stroke, nerve disorders and neurodegenerative diseases. Studies have revealed that astrocytes play an important role in restoring neuronal cells and protect neurons against oxidative stress. Tocotrienols help in preventing glutamate-induced injury and prevent the death of astrocytes. Therefore, tocotrienols are crucial in minimizing neurodegenerative diseases and stroke.

Annatto

6. There are several studies and clinical trials showing evidence of anti-inflammatory effects of tocotrienols by controlling the inflammatory mediators. Research suggested that tocotrienols block the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB), one of the main regulators of inflammatory response. Supplementation of tocotrienols is found to reduce tumour necrosis factor alpha (TNF-alpha), interleukin-1 and phorbol ester. It is a potential agent with significant anti-inflammatory effects in atherosclerosis, thyroid diseases, and autoimmune diseases.

7. Research shows that tocotrienols are usually safe for healthy individuals at a minimum dosage. But they do have anti-coagulant properties, so people with blood disorders should avoid taking them. Some contraindications:

• Individuals allergic to any compound of Vitamin E should strictly avoid it.

• As mentioned already, people with bleeding disorders, or anyone who will undergo surgery, should avoid it as it may slow blood clotting.

• Tocotrienols may interact with medicines like anticoagulants and antiplatelets and increase the risk of bleeding.

• Overdosing should be avoided as it may cause physical symptoms like headache, fatigue and GI symptoms.

•High doses of tocopherol can interfere with the efficacy and absorption of tocotrienols.

8.Tocotrienols are generally safe when taken by mouth. There is no standard medical recommendation for dosage. However, under medical supervision, the typical dose of tocotrienols in adults is 100mg – 200mg per day. Dosage can vary depending on the specific health requirement. Supplements are mainly derived from palm and annatto derivatives. They are fat- soluble and best absorbed along with a meal.

Edible oils

9. Food sources: Generally, tocotrienols are rarely found in nature. Even if some food sources are available, they are available in very low quantities. Palm oil has the most concentrated and natural source of tocotrienols, but at a very low level, which is not sufficient for potential health benefits. Other food sources are annatto ,edible oils like rice bran oil, grape seed oil, castor oil, coconut oil, peanut oil, linseed oil, cod liver oil, hazelnuts, oats, olive oil, maize, wheat germ, nuts and barley. Fish like salmon, trout, fruit like avocado, mango, vegetables like red pepper, greens, turnip, and squash are rich in vitamin E and its compounds.

10. Takeaway is that tocotrienols are the least known compound of the Vitamin E family, yet they are the most potent antioxidant and have strong evidence of widespread health benefits. Newest studies show that this compound has senolytic properties, a strong immune response, and apoptosis. They can slow down the process of ageing, reduce oxidative stress, and lower malignant potential. Though in small quantities, regular intake of natural sources of tocotrienols is sufficient for a healthy individual. Supplementation is required when medically prescribed.

Thanks for reading.

Peace and love 🙏

10 facts about Fucoxanthin (FX): A promising natural supplement 🙌

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Flavonoids, antioxidants, anti inflammatory, Fucoxanthin, chlorophyll, algae, seaweed, seafood, healing, health, Infection,inflammation, Inflammation, diseases, environmental damage, health issues, nature, Obesity, weight loss, Supplement, wellness

1. Fucoxanthin (FX), a brown pigment, is derived from various seaweeds and algae. It helps in algae photosynthesis and photo-protection in the aquatic environment. Several studies have shown that this phytochemical can be a potential source of nutritional and health benefits against various diseases like diabetes, obesity, cancer and many infectious diseases. Recent findings have shown that it has various properties like antimicrobial, antioxidant, anti-inflammatory, anti-obesity, anti-diabetic, and hepato-protective effects. Therefore, because of its highly potent effects of prevention of obesity related diseases, anti-cardiovascular, tumour inhibition and health benefits to bones, skin, eyes and liver, this pigment has been a promising pharmaceutical asset.

2.Molecular Structure: The unique molecular structure of FX is similar to that of Beta carotene and has the allenic bond. Out of 700 naturally occurring carotenoids, only 43 of them belong to the allelic group, and FX is one of them. Therefore, there is growing interest in the pharmacological activity of this carotenoid, which can be a great potential source towards the prevention of various physical illnesses. FX is mainly found in micro-algae rather than macro-algae. Among the three kinds of micro-algae, that is green, red and brown algae, FX is in higher concentration in brown algae.

3. Multi-functional: Research has already shown that FX has a tremendous amount of health benefits because of its unusual molecular structure. The multi-functional benefits are namely, anti-oxidant, anti-microbial, anti-inflammatory, anti-allergic, anti-malarial and anti-helminthic. Apart from these activities, FX helps to correct the imbalance of lipid metabolism, which is created by a fatty, unhealthy diet. It has a positive impact on fatty acid oxidation, lipolysis, and bile acid synthesis and lowers the level of free fatty acids.

4. Anti-obesity effects: This brown pigment is a promising asset for lowering weight naturally. Obesity has been one of the main risk factors of many chronic and serious health issues like diabetes, heart diseases, high blood pressure, atherosclerosis, fatty liver, high cholesterol, infertility and many cancers. FX lowers the free fatty acids, inhibits lipogenesis, promotes beta-oxidation, bile synthesis, and influences enzymes which are essential for lipid metabolism. As a result, fat accumulation in the liver and adipose tissues is lowered, reducing cholesterol and triglyceride concentration.

5. Liver: Studies have shown that FX has hepato-protective effects. In case of fatty liver diseases, it can help in reducing the accumulation of lipid in liver cells, stimulate Beta-oxidation of hepatic fatty acids and lower the hepatic enzyme activity for fatty acid synthesis. Several animal studies have shown promising results of reducing lipid and triglyceride concentrations in the liver.

6. Inhibitory effect on cancers: Several studies on different cancers have shown that FX can scavenge free radicals and make it a potential modulator of carcinogenesis. FX has shown promising outcomes in different animal studies of inhibiting apoptosis and hindering the tumorigenesis in different types of cancers like lung cancer, colon cancer, breast cancer, liver cancer, gastric cancer, lymphoma and leukaemia. They behave as angio-modulators in cancer therapy.

7. Metabolism of FX: Because of its wide range of health benefits and potential role in the prevention of chronic illnesses, it has been a promising compound in pharmacological uses both individually and in synergy with other compounds. FX is a carotenoid which is mainly absorbed in the small intestine, similar to fats and fat-soluble vitamins. Studies have shown that consumption of this brown pigment orally does not show abnormal changes in organ tissues; therefore, it is safe for human use.

8. Food sources of FX are various species of seaweeds like Wakame, Arame, Kombu, Hizika and Laminaria digitata. Some other natural sources are microalgae like diatoms. Marine invertebrates like mussels, oysters, and clams also contain a small amount of FX. Predominantly, FX is present as a rich source in brown seaweed compared to other pigments like chlorophyll and xanthophylls.

9. As a supplement: Animal studies have shown the safe use of FX and that it has no adverse effect on the body. Therefore, it has been widely used as a supplement for its wide range of health benefits. It is used as tablets, capsules and soft gels usually labelled as Fucoxanthin or “brown seaweed pigment” While the bioavailability can be low in case of human consumption, its absorption can be increased when consumed with lipids and edible oils. Dosage can vary from 3-5 mg per day.

10. Side effects: FX has no adverse effects and no toxic accumulation in the vital organs of the body in case of animals when consumed in higher doses. Therefore, it is considered safe for human consumption. It is considered safe for vital organs like the liver, kidney, spleen and gonads when consumed moderately in humans. Further research on humans is still required for more clarification. It is always advisable to consult a Physician before introducing FX as a supplement when there is a pre-existing medical condition.

Thanks for reading.

Peace and love 🙏

10 facts: Is hydrogen water a hoax or is it real?

by drjurisharma, posted in antioxidant, Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, healing, health, Heart friendly, weight friendly, gut healthy, constipation,, Hydrogen, hydrogen water, hydrogenated water, Inflammation, diseases, environmental damage, health issues, Science, wellness

1.Hydrogen water, also known as hydrogenated water, is simply regular water infused with hydrogen gas. The regular water is H2O with extra H2 gas added, which is what makes hydrogenated water. This hydrogen-rich water has become quite popular nowadays as it has been found to have health benefits. Manufacturers are now selling hydrogen water bottles across the globe for it’s health benefits. Extensive research has not been done so far, regarding the use of hydrogen water. Yet, it has been very popular in some countries, such as Japan.

2. As far as nutritional benefits are concerned, hydrogen water is the same as regular water in terms of calories, protein, fat, and carbohydrate which is nil. However, some manufacturers and providers do add trace amounts of vitamins A and C, magnesium, potassium and sodium sulfate to enhance the nutritional benefits. As already mentioned, not much research has been done in this context, but some experts do believe that drinking hydrogen water is beneficial for health.

3. Anti-inflammatory: Hydrogen water does contain anti-oxidants. Anti-oxidants fight inflammation and reduce oxidative stress. Every day, our body is inflicted with various types of physical and mental stress, which comes from external forces like pollution, sun exposure, toxins from the environment, food, day-to-day mental stress of various nature, also from normal body functioning, all these factors are sources of inflammation, diseases and cancers. Therefore, molecular hydrogen can help to some extent to combat oxidative stress and reduce inflammation.

4. Endurance and Mental health: Several studies have shown some positive results of increasing endurance and lowering fatiguability after drinking hydrogen water. It does show performance improvement, increasing energy, and endurance in the case of athletes, though scientifically, still not verified. It has been found to lower physical stress and reduce recovery time after heavy workouts.

Some studies on mental health have shown that drinking hydrogen water daily for 4 weeks showed marked improvement in mood disorders, panic disorders and anxiety.

5. COVID-19: More research is still needed to establish the fact, that hydrogen water consumption did slow down the immune response which is known as a “cytokine storm”. The use of hydrogen water was useful to reduce the cytokine response of Covid 19 virus which otherwise could lead to organ failure. But, as already mentioned, more studies are required to clarify that hydrogen water can potentially treat Covid 19.

6. Liver and kidney functions: Studies of cases of non-alcoholic liver diseases, cases of hepatitis –B virus, drinking hydrogen water has shown positive results in lowering fat storage in the liver, aiding the treatment process and improving the liver function. But then, research is limited in such cases too. A study on dialysis patients has shown, that intake of hydrogen-rich water caused improvement in renal function and BUN (blood urea nitrogen).

7. Cancer treatment: Hydrogen water does show positive results in aiding cancer treatment. Since hydrogen water contains anti-oxidants, and acts as an anti-inflammatory, an immune booster does give promising results during cancer treatment by improving both physical and oxidative stress. A study regarding colo-rectal cancer showed anti-cancer properties.

8. Metabolic syndrome: Metabolic syndrome is a condition which includes high blood pressure, high cholesterol, high triglycerides, obesity or excess belly fat. The risk factors of metabolic syndrome are oxidative stress and chronic inflammation. Some studies have shown that intake of hydrogen water around 1 litre daily, in individuals on a 10-week study marked a significant reduction of risk factors of metabolic syndrome and showed a favourable effect on the metabolic processes in the brain and even ageing.

9. Negative effects: As far as health experts are concerned, there are no known side effects of drinking hydrogen water. Research is still not enough to establish even the health benefits thathave been claimed so far. More studies are required to verify the health benefits. In the case of individuals with high-intensity workouts, athletes, and chronic kidney diseases, there can be a risk of hyponatremia in drinking excess hydrogen water.

10. Though several studies do show potential health benefits of drinking hydrogen water over regular water, but still, continuous trials and more studies are still required to establish the benefits. Many manufacturers are selling hydrogen water bottles which are quite expensive. Again, depending on the source of water, the authenticity of brands is important to avail the actual health benefits claimed. The bottom line is that there is still not 100% proof of the potential health benefits. If affordability is there, there is no harm in using hydrogen water for drinking, otherwise, regular drinking water is great as well.

Thanks for reading.

Peace and love 🙏

10 facts: Desquamation or Skin peeling, is it a sign of skin healing ? 🙌

by drjurisharma, posted in Acne, blackheads, pimples, Dermatology, derma, epidermis, skin care, Eczema, psoriasis, contact dermatitis, cancer, healing, health, meditation, inflammation, disease, physical health, mental health, wellbeing, Petroleum jelly, humidifier, moisturizer, Skin, skin peeling, desquamation, skin healing, wellness

1. Skin peeling is the shedding of the outer layer of the skin called the epidermis. It is a natural process of the body to shed the outer skin that has been damaged due to various causes and replace it with new skin. Skin peeling is a healing process of the skin from damage caused by allergies, skin infections, environmental pollutants, diseases, and treatments like cancer therapy. The medical term for the same is desquamation.

2. As already mentioned, the outer layer of the skin is important as it protects the body from germs and external elements. This epidermis is the thinnest layer and is also responsible for the new skin cells that replace the older and peeled skin. Peeling skin appears scaly, inflamed, red, and even irritated and itching. So, picking may further irritate or infect the new skin that is about to grow.

3. Causes of skin peeling can be many:

• Sunburns

• Burn: A superficial burn causes the skin to peel as the epidermis is burnt and damaged.

• Allergies, rashes, contact dermatitis

• Psoriasis, eczema, Pemphigus

• Acne

• Anti-ageing treatments like chemical peeling, cosmetic creams with harsh chemicals, lotions

• Cancer treatments like chemotherapy and radiation therapy.

4. Some of the medical causes which can cause skin peeling that need to be known :

• Eczema is a skin condition whose common symptom is skin peeling. This condition can be treatable and controlled but cannot be cured.

• Scarlet fever can cause skin peeling and rashes which is contagious.

• Scalded Skin syndrome (SSS) or Ritter’s disease can cause skin peeling, rashes and large blisters in children under 5 years of age and also in adults with weak immunity. It is caused by a toxin produced by staphylococcal bacteria.

• Toxic shock syndrome is a rare and serious condition which might cause skin peeling too. It is usually associated with women due to tampon use.

• Kawasaki disease in children can cause skin peeling too along with other symptoms like fever and swollen lymph nodes.

5. Whenever skin peeling happens, the process is slow and should let it shed naturally without interference. However, we can take some steps which will facilitate the process naturally. *Having fluids to keep the skin hydrated. *Apply a hypoallergenic moisturizing cream or a lotion to keep the skin moist and hydrated. *Protect from sun damage by wearing protective clothing.

*Using a humidifier to keep the air hydrated.

6. There is not much concern about skin peeling than its complications which surely need medical attention. Skin peeling is slow and sloughing off takes time. Dehydration of the skin can cause irritation, itching and pain. If there is picking or any complications like bacterial infections, swelling, hives, fever, redness, headache, flu-like sensations, it has to be treated with urgency under medical supervision otherwise it will worsen.

7. Research indicates that the process of desquamation is both natural and essential for maintaining healthy skin. This process, which can be influenced by both natural and medical factors, occurs slowly and serves as a protective mechanism for the skin. It helps remove surface microorganisms, damaged skin cells (corneocytes), and potentially harmful agents, replacing them with fresh, healthy skin.

8.Treatment for skin peeling is generally unnecessary unless there are underlying conditions. The appropriate medication will depend on the specific causes, which may include:

-Antibiotics- Anti-inflammatory medications

– Allergy medications

– Corticosteroids

– Antifungals

– Antihistamines

In cases where no underlying condition is present, using a good petroleum jelly or a non-allergenic moisturizer, along with proper hydration, is usually sufficient to aid in the healing process.

9.Studies show that the process of epidermal desquamation is a healing process with therapeutic relevance. Non-inflammatory skin peeling is typically non-problematic and has a good prognosis. In contrast, inflammatory skin peeling can be associated with atopy and requires medical intervention. Epithelial desquamation involves the shedding of old, dead cells and their replacement with new skin, while keratinization refers to the maturation of skin cells. Both processes are interconnected and essential for maintaining skin integrity.

10. In a nutshell, desquamation is a common process and is not something to be overly concerned about, as it is a natural occurrence. Symptoms such as scaling, dryness, and itching are typical and gradually resolve as the skin is replaced with a new surface. However, it can become a concern in the presence of conditions such as contact dermatitis, eczema, psoriasis, sunburn, ichthyosis, or bacterial infections, which require medical attention.

Thanks for reading.

Peace and love 🙏

8 facts: Burning mouth syndrome or Glossodynia 👅

by drjurisharma, posted in Adult over 50, Blog, Burning mouth syndrome, BMS, Females, perimenopause, menopause, healing, health, Hot beverages, life, Mouth, tongue,lips, wellness

1.Glossodynia, also known as Burning Mouth Syndrome (BMS), is a fairly common condition. It’s an intermittent burning sensation in the mouth, especially in the tongue, lips, or other areas of the mouth, that is not accompanied by a specific reason. It feels as though the tongue is injured by a very hot liquid. The syndrome may be gradual or sudden in onset. There is no observable physical sign seen either in the tongue or in the mouth while having an episode. The specific cause of BMS is difficult to determine.

2. Most causes of burning mouth syndrome are unknown or idiopathic. Research suggests that it can be related to nerves which carry sensations of taste and pain. The causes are broadly divided into primary and secondary. Primary burning mouth syndrome is uncommon and mainly idiopathic.

3, Secondary burning mouth syndrome is quite common and causes can be related to :

* Vitamin deficiency like Vitamin B complex, lack of iron, zinc ,folate.

* Oral infections like oral thrush, oral lichen planus.

* Allergies following food additives, flavouring substances, mouth care products.

* Acidic drinks, extreme hot liquids, irritating foods like highly spiced foods.

* Dental materials, ill-fitted dentures.

* Dry mouth due to some medicines like anti hypertensives, anti cancer treatments.

* Reflux or Gastro esophageal reflux.

* Endocrine issues like diabetes, hypothyroidism.

* Anxiety, stress, depression.

Hot spicy food

4. Burning mouth syndrome, (BMS) can occur in any individual irrespective of age and gender. But the common risk factors are seen mostly:

* Females.

* More common over the age of 50.

* Post menopausal or perimenopausal women leading to low estrogen levels affecting taste buds.

* Smoking.

5. When a person experience BMS, there is no visible symptoms like discolouration of tongue or bumps. The symptoms found are :

* Altered taste, or metallic taste or loss of taste.

* Tongue and mouth feels like scalding, burning or tingling.

* Dryness of tongue, lips, gums.

* Numbness in the mouth.

Sipping cold water

6. BMS treatment and diagnosis are individual specific depending upon the symptoms. Diagnosis can be done by a saliva or oral swab tests. As far as treatment are concerned, there is no approved drugs. Remedies are there to ease the symptoms like :

* Mild mouth rinses.

* Saliva substitue like Biotene.

* Getting enough vitamin B complex, iron and folate.

* Pain relievers if necessary.

* Sipping cold water or ice chips.

* Sugar free gums chewing to encourage saliva production.

Hot beverages

7. Though it is not always possible to prevent BMS. But,if we are prone to BMS or have been affected in the past, it is important to avoids certain things :

* Very hot liquids, hot bevereges or drinks like highly acidic ones.

* Hot or spicy food.

* Alcohol

* Mouthwash containing alcohol.

* Smoking.

8.Feeling fire, irritations, and a burning sensation in the mouth, you can be sure to have Burning Mouth Syndrome, which is frustrating and irritating. But, once you have acquired it, it takes a while to go away. You can take the above-mentioned remedies and precautions till it heals. But, if there are flare-ups or hasn’t gone for long, you should surely visit your Physician or Dentist.

Thanks for reading.

Peace and love 🙏

8 facts: Are CoQ10 supplements actually necessary ? 🙌

by drjurisharma, posted in antioxidant, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, butter,dairy,inflammatory,disease,cancer,gut health,, cognitive health, Flavonoids, antioxidants, anti inflammatory, healing, health, Heart disease, life, meditation, inflammation, disease, physical health, mental health, wellbeing, Parkinson disease, migraine, fertility, Science, Supplement, Coenzyme, Q10, wellness
CoQ10 supplement

1.We have often encountered a supplement named CoQ10, commonly seen in the drug aisle of a supermarket. Let’s know, what exactly CoQ10 is. Well, it is Coenzyme Q10, a fat-soluble, vitamin-like molecule, which is naturally present in every human cell. It is a powerful antioxidant that converts food into energy. Like all other antioxidants, it can neutralize the free radicals and prevent oxidative stress. Therefore, it can prevent us from many chronic health problems and slow down the ageing process.


2.Clinical studies have suggested that CoQ10 plays a significant role in:
It may help in preventing heart-related problems.
Improving the overall immunity.
Improve physical endurance.
Improves male fertility.
Prevent migraine.
Improves blood sugar level in diabetes.
Supports treatment of neuro-degenerative disease like Parkinson’s disease.


3.Evidence-based studies show that people who have a history of heart failure show reduced incidence of heart attack when they take CoQ10 supplements daily along with conventional medications. But then, it has to be prescribed or taken under expert guidance. Several studies have shown similar preventive or improvement levels in cases of heart issues like high cholesterol, high blood pressure, congestive heart diseases and heart damage caused by chemotherapy.


4.CoQ10 supplements have no approval from the FDA or other Drug Regulatory Authorities for the treatment of any medical conditions. However, yet it is easily accessible and available as the over the counter supplements and has been quite popular. It is often recommended as a dietary supplement by many Physicians and Specialists as a supportive therapy to conventional
treatments.

Food sources

5.Naturally dietary sources of CoQ10 intake are enough for overall well-being. Dietary sources are wide variety of whole grains and oily fishes. CoQ10 supplements are not necessary for a healthy individual who has a balanced diet. Supplements of CoQ10 is only necessary for those who suffer from CoQ10 deffeciency, or have health issues like heart disease, migraine, neuro-degenerative
disease or other chronic health conditions. It is not advisable to pick a supplement bottle from the supermarket aisle and start popping unless clinically recommended.

Nuts and seeds

6.As already mentioned, the human body makes enough of CoQ10 as much as it needs. The body content is about 500 to 1500mg and it declines with ageing. The food sources are organ meats, fatty fishes like salmon, sardines, trout, mackerel. As for vegetarians, soya products like tofu, soy milk, and soy yogurt are good food sources. Nuts and seeds, lots of vegetables including broccoli are rich sources of CoQ10.


7.Though CoQ10 supplements do not have major risk or side effects, it is still not advisable to take unless necessary for specific health issues. Some side effects of supplementation can be diarrhea, nausea, heartburn. It may interact with medications like blood thinners with further lowering of blood pressure, or in case of diabetes, subsequent lowering of blood sugar along with hypoglycemic drugs.


8.Due to certain chronic health issues like heart problems, migraine, fertility issues or
neurogenerative conditions, Physicians do recommend CoQ10 supplements. There is no standard dose as such. Depending on the individual’s requirement, dosage varies from 60-500 mg daily. The highest dose recommended daily is about 1200 mg. As it is a fat-soluble substance, it is best absorbed with a fatty meal and better if taken at night.

Thanks for reading.

Peace and love 🙏

Butyrate is the latest buzzword! Is it just a hype or the reality? 10 facts 🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, butter,dairy,inflammatory,disease,cancer,gut health,, butyrate, dairy, curd, yogurt, detoxification, vegetable,, Food, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, life, Science, wellness
Butter is a rich source of butyrate

1.Butyrate is a short-chain fatty acid (SFCA) released during the fermentation of dietary fibres by the gut microbiome. It plays an integral part in supporting gut health and overall well-being. It is an energy source for colonocytes which meet about 70% of their needs. Evidence has shown that this SFCA has tremendous health benefits ranging from immunity support, lowering inflammation, preventing cancers and fighting ageing. Hence, it is the latest buzzword, doing rounds in social media and among advertisers.

2.Recent studies have clearly shown that butyrate plays an important role in both the host and microbial functions in gastrointestinal health. It is a crucial energy source for colonocytes. An optimal level of butyrate promotes and maintains a healthy microbiome level, reduces inflammation, and supports colonocyte functions. It has protective actions against certain intestinal diseases like inflammatory bowel diseases and colon cancer.

3.Butyrate has been shown to prevent the process of inflammation in the gut which can be caused by pathogens, the body’s overreaction (allergic reactions) and oxidative stress. Chronic inflammation in the gut occurs when the gut’s immune system is constantly fighting against these pathogens and free radicals causing the immune health to be weakened. Eating a considerable amount of fibres causes to production of an optimal level of butyrate which helps in protecting against this inflammatory process.

Dietary fiber is a good source of butyrate

4.Studies have shown a great impact of butyrate on obesity. Butyrate is found to lower body weight and decrease lipogenesis in the liver and adipose tissues. It increases fatty acid oxidation and prevents fat accumulation in the body thereby reducing obesity. Butyrate is produced by the fermentation of dietary fibres, so it suppresses the food intake and reduces body weight and fat mass.

5.Animal and cell studies have shown that butyrate increases insulin sensitivity, helps in reducing weight gain, and obesity and promotes weight loss. It helps in maintaining blood sugar levels.

Dairy products

6.Another significant property of butyrate has been shown in research that it promotes cell differentiation. Normally, our cells have the ability to change into any specific type of body cells required like liver cells, heart cells, intestinal cells or blood cells. If the cells are not properly differentiated, then, abnormal growth or tumour appears. Butyrate is found to promote cell differentiation.

7.Studies have shown that butyrate plays an important role in the brain-gut connection. It helps in increasing Brain-Derived Neurotrophic Factor (BDNF), removes toxic byproducts from the brain and prevents brain fog. It promotes neuroplasticity and improves rapid eye movement sleep by 70%.

8.Butyrate helps to regulate the blood pressure level. Studies show that the level of butyrate inversely corresponds to the blood pressure level. A higher butyrate level gives a lower blood pressure level while low butyrate may lead to the rise of high blood pressure.

Leafy veggies

9.Sources of butyrate are :
Dietary fibres like vegetables like garlic, onion, tomatoes, beans, peas, leafy vegetables, broccoli. Fruits like bananas, apples, pears, kiwis.
Whole grains like brown rice, oats, wheat, barley, rye and pulses, legumes.
Dairy sources like milk, cheese, butter, and ghee.
Others like dark chocolate, seeds, nuts, and seawood.
Butyrate supplements are available in the form of sodium, calcium/magnesium butyrate but need to be used as per supervision as they may interfere with other medication.

10.It is important to know that consuming full-fat dairy products like butter, Ghee, cheese, and milk are rich sources of butyrate. However, consuming these products can cause the risk of elevating the level of cholesterol in the body as they are rich in saturated fatty acids too. Therefore, the risk of cardiovascular diseases and obesity may rise. So, the key point to be noted while consuming these products is having them in moderation along with lots of dietary fibre and plenty of water can benefit and maintain the balance.

Thanks for reading.

Peace and love 🙏

10 facts to know about constipation 👐

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, constipation, bowels, colon, bowel movements, bowel disease, deep fried food, detoxification, vegetable,, emotional health, french fries, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, mental health, milk, dairy, curd, yoghurt, muscle, body, Science, stomach, abdomen, intestines, wellness
  1. According to medical terminology, constipation is when a person has irregular bowel movements, usually less than three times a week. Normally, a person with regular bowel movements has stool elimination three times a day to three times, a week. Constipation has been the most common gastrointestinal issue affecting millions of people daily.
  2. Normally, the food passes through the large intestine, and the water is absorbed in the colon while forming the faecal matter or stool. Then, the stool formed in the colon is pushed down to the rectum by muscle contraction. If the muscle contraction in the colon is prolonged, by the time, stool reaches the rectum, more water is absorbed making the stool too hard to pass. Passage of the dry hard stool becomes very difficult causing constipation.
  3. The most common causes of constipation are: Lack of movement, lack of exercise, stress. Lack of fibre in the diet.
    Not drinking enough fluids.
    Changes in dietary habits, pregnancy, traveling, ageing. Medications.
    Irritable bowel syndrome.
    Anal fissure.

4.Common symptoms of constipation:

Pain abdomen.
Painful bowel movements.
Feels uncomfortable or bloated.
Bowel movement less than 3 times a week.

5.Generally, constipation is relieved by switching the diet to more fibrous food, more intake of fluid, and exercise. However, if the person is not relieved of the symptoms despite these above- mentioned measures and maybe, there is a history of blood in stool, episodes are more frequent, then, it is necessary to seek medical attention.
Diagnosing constipation is based on medical history, a physical examination which covers an anorectal examination, barium enema, and colonoscopy.

6.Constipation is usually treated by diet and lifestyle changes.
Lifestyle changes include regular exercise, more intake of fluids in the daytime, giving enough time for daily bowel movements.
Dietary intake of at least 20-30 grams of fiber daily, including whole grains, fruits like bananas, pineapple, papaya, oranges, apples, kiwis, berries and vegetables, is recommended.
Changing the existing medication if any.
If the above measures don’t work, then laxatives are prescribed.

7.Certain risk factors which may lead to constipation:
*Mental health issues: Due to depression and stress-related issues leading to unhealthy diet, irregular meal timing, anti-depression medication, lack of exercise, and eating disorders.
*Old age causes weakening of the muscle lining so sluggish bowel movements.
*Pregnancy causes the bulky uterus to press against the intestinal wall making it harder to defecate.
*Eating lots of refined food, junk food and not eating enough fibre causes hard stool. *Medications like iron pills, antacids, blood pressure medicines, allergy medicines, anti- depressants.
*Diseases: Stroke, paralysis, Parkinson’s disease, diverticulitis, multiple sclerosis, irritable bowel disease, colon cancer.

8.Constipation commonly occurs in most cases due to dietary changes or lack of physical activity. The condition is resolved usually by changes in diet and lifestyle. But, it can be a warning sign and may require immediate medical attention when:
there is severe cramping pain with sudden onset of constipation.
Blood in stool.
Loss of weight.
Severe pain with bowel movements. Constipation is for a prolonged period.

9.Generally, dietary and lifestyle changes can prevent constipation : Drinking 3-4 glasses of water every day.
Adding vegetables and fruits to your diet every day.
Routine physical activity and exercise is a must.
Eating Probiotics such as curd, yoghurt or kefir daily. Avoiding processed food, processed meat, and fried food. Drinking less alcohol and caffeinated drinks.
Not ignoring the urge to poop.

10.There are several different laxatives available, just for your information.
Osmatic laxatives like milk of magnesia cause softening of stool.
Stimulant laxatives increase the speed of bowel movements to help the stool to move through. Lubricant laxatives like mineral oil lubricate the intestine and help to slide the stool along the colon.
Saline laxatives are used as enemas to empty the bowel.

Thanks for reading.

Peace and love 🙏

Are popcorns 🍿 healthy ? 9 facts 🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, deep fried food, eyes, Food, glutathione, antioxidant, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, popcorn, Science, skin, cancer, anti inflammatory, plant, nature, medicine, herb, stomach, abdomen, intestines, Uncategorized, wellness
  1. Popcorns are corn kernels which get popped when heated. Today, across the world, this has become the most popular snack amongst all age groups. Corn is the oldest grain which has been consumed for over 5000 years. It has been popular due to its easy availability and low cost. As far as health point of view is considered, it is a whole grain food, rich in fibre, low in calories and dense in nutrients.
  2. Studies show that popcorn is high in fibre and contains many vitamins and minerals. Important nutrients in popcorn are vitamins B1, B3, B6, iron, potassium, manganese, zinc, copper and phosphorus. Many studies also show that it is rich in polyphenols which are potent antioxidants. Polyphenols reduce the risk of damage by free radicals, diabetes, and heart disease and improve gut health. Popcorn is gluten-free so it can be a healthy option for people with gut issues.

3.Since, it is high in fibre and low in calories, it can help in weight loss. Eating a cup of popcorn which is around 30 calories can relatively be more beneficial in terms of fibre and nutrient content than any other popular snack. Also, it can give the feeling of fullness and curb your hunger for quite some time. Therefore, eating in moderation of popcorn can be very useful in the process of weight loss in an overweight individual.

4.Popcorn contains antioxidants Zeaxanthin, beta carotene and lutein which are very essential to eye health. These antioxidants can slow the age-related macular degeneration of the eyes, lower the damage caused by blue light and overall improve the eyesight.


5.Other health benefits of yellow popcorn are :
*Boost the metabolism and energy production due to the presence of vitamins B, B3, B6 and folate.
*Popcorn contains niacin which helps to reduce depression naturally.
*Phosphorus, and manganese present in popcorn help to support bone health.
*Popcorn can combat tumour cells due to the presence of ferulic acid.
*It can reduce the level of bad cholesterol and prevent the risk of heart disease.
*It can slow down the process of ageing as it helps in free radical damage.
*It can add iron (28 gm of popcorn containing 0.9mg of iron) to the diet and reduce anaemia. *It can control blood sugar as it has a low glycaemic index and helps in diabetics.

6.Air-popped popcorn is healthiest. Unsalted popcorn, unflavoured is healthier than those with an excess of oil, butter, sugar, caramel, and salt. Microwave popcorn bags which are pre-packed contain the chemical perfluorooctanoic acid (PFOA) and sometimes, trans fat which are harmful to health.


7.Popcorn added to diet in moderation can prove to be safe and beneficial to health. But it may have side effects on certain individuals. Some individuals can have allergic reactions to popcorn like swollen face, and breathing difficulty which may require urgent medical attention. People with digestive diseases and inflammatory bowel disorders can have flaring-up symptoms when consuming popcorn.


8.Popcorn is the ideal choice for adding to your diet in moderation. You can definitely enjoy popcorn daily, as long as you stick to one cup per day without any butter, salt, sugar, or artificial flavors. This will provide a healthy dose of whole fiber content, making it the most nutritious snack option for your diet.

9. Yellow corn which is organically grown, non-GMO, is best for regular consumption. Popcorn which is popped from such type of high-quality corn, air popped with no added flavours is ideal and provides immense health benefits. Rich in phytonutrients, vitamins, and minerals, whole grain fibres can help to reduce the risk of chronic illnesses, obesity, diabetes and many malignancies.

Thanks for reading.

Peace and love 🙏

10 facts about Cheilitis or chapped lips 👄

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, healing, health, life, physical therapy, pain, body aches, spinal,, Uncategorized, wellness
  1. Chapped lips are common and can happen any time of the year irrespective of season. When lips are dried, cracked and feel tight, they are called chapped lips or Cheilitis. As the skin on the lips contains no oil glands, they are thinner and more sensitive, hence chapped lips are common. Most of the time, it is common in dry winter, or excessive sun exposure, dehydration or excessive licking.
  2. Cheilitis or chapped lips is inflammation of the lips and can be of different types depending on the sources.
    Due to allergic reaction called contact cheilitis.
    For sun exposure called actinic chelitis.
    Reaction to certain drugs like retinoids causes drug induced cheilitis. Fungal infection of the mouth causes angular cheilitis.
    Herpes infection causes infective cheilitis.
    Persistent painless swelling of the lips causes granulomatous cheilitis. Frequent licking of the lips causes exfoliative cheilitis.

3.Certain risk factors which can cause cheilitis are nutritional deficiency of vitamin B12 and iron, certain medical conditions like thyroid disease, autoimmune conditions like Lupus erythematosus, Sarcoidosis, Crohn’s disease, dermatitis and allergic reaction to cosmetics. Metabolic diseases like diabetes, certain irritants, climatic effects and oral candidiasis can cause cheilitis.

4.Diagnosis: Chapped lips are common and temporary. When lips are cracked, swollen, or tight, then, they are called chapped lips or cheilitis which can be easily diagnosed visually. A long-term occurrence of chapped lips may be required for medical attention. Usually, an allergy test, blood work and sometimes a biopsy are required for a proper diagnosis. Bleeding is common from cracked lips which can be easily managed by a lip balm or ointment. If bleeding is frequent, then medical attention is necessary for the diagnosis of the underlying cause.

5.Treatment:Whenever chapped lips appear, it is important to apply lip balm immediately, so that it will heal faster and leave no scope for infection. Wearing lip balm regularly will heal the lips faster within a week. When bleeding occurs from cracks, cuts, or sores from the lips, there is pain and irritation. In that case too, continuously applying lip balm, ointments like petroleum jelly, glycerin or mineral oils like castor oil can be used for healing which may take longer. Lip balm needs to be hypoallergenic, moisturizing and with sunscreen SPF preferably.

6.Crevices: People with more skin creases, either anatomically or due to ageing, are more prone to developing cheilitis. This is because saliva from the mouth can accumulate in the lip crevices, leading to inflammation and cheilitis. Elderly individuals, smokers, those with sensitive skin, and ill- fitted dentures, and people who drool during sleep are also prone to cheilitis. Additionally, individuals with Down syndrome have a higher likelihood of developing cheilitis.

7.Symptoms of cheilitis of any type can have common characteristics like: *Dryness
*Cracked or fissures
*Peeling
*Itching *Redness *Bleeding
*Pain or irritation

8.Medication: Apart from lip balm, vaseline, petroleum jelly and glycerine, there are certain medication options for different types of cheilitis.
*For contact cheilitis, topical corticosteroids and emollients like Vaseline can be used.
*For angular cheilitis, topical antifungal and antiseptic ointments are used. *For Drug induced cheilitis, firstly discontinuing the use of the drug and applying emollients can be useful.
*For actinic cheilitis, applying topical corticosteroids is useful.

9.Prevention:
Preventing frequent licking of lips.
The routine habit of applying either petroleum jelly, lip balm, beeswax, or lip products with SPF (zinc oxide).
Staying hydrated in hot summer and using a humidifier in cold dry climates.
Avoid irritants like fragrance, allergens, and food that can irritate.
Breathing through the nose rather than the mouth.
Covering face and lips in dry windy weather.

10.Products: Since the market is flooded with various lip products, many people are allergic or sensitive to certain products. While trying a new lip balm, if there is burning or tingling, it is important to stop using the product immediately. Common irritants used in lip products are flavouring agents, fragrances, menthol, camphor, lanolin and many more. The best product for chapped lips has been the age-old petroleum jelly or the glycerine.

Thanks for reading 😊

Peace and love 🙏