Tag: blogger

10 compelling reasons to consume Flavanoids to combat oxidative stress 🙌

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, detoxification, vegetable,, emotional health, Flavonoids, antioxidants, anti inflammatory, Food, Fresh, local, produce, Fruits, veggies, berries, healing, health, life, meditation, inflammation, disease, physical health, mental health, wellbeing, nature, self healing, wellness
  1. Flavonoids are naturally occurring polyphenolic compounds in various deep-coloured fruits and vegetables. There are 6 different varieties of flavonoids, all of which have antioxidant properties and can help the human body to get rid of different toxins and stress. Therefore, including flavonoids in your routine diet can help to get rid of many chronic health conditions.
  2. Dietary Flavonoids are of 6 subtypes :
    Flavanols , Flavones, Flavan-3-ols, Flavanones, Isoflavones, Anthocyanins.
    Coloured fruits, vegetables, and plants are all rich in flavonoids. Naturally, they are found in apples,purple and red grapes, berries, peaches, oranges, cocoa, chocolate, green tea, black tea, chamomile tea, vegetables like broccoli, lettuce, tomatoes, scallions, red peppers and onions. Flavonoids are dark-coloured pigments so they act as natural pesticides and protect the plants from harmful UV rays, bacteria, viruses and harmful insects.

3. Main functions of flavonoids:
•Powerful antioxidants
•Fights inflammation
•Free radical damage and prevent oxidative stress.

•Anti-haemorrhagic and vasodilatory effects.
•Certain flavonoids, due to their anti-inflammatory and antioxidant properties prevent cancer cells from multiplying and decrease the risk of some cancers.

4.Research shows that oxidative stress can lead to cellular damage and disease development. So, oxidative stress can cause many disease conditions like cancers, diabetes, cardiovascular diseases like hypertension, atherosclerosis, chronic inflammatory diseases, and neurodegenerative diseases. Flavonoids play an important role in reducing this oxidative stress and free radical damage, thereby preventing cellular damage.

Cocoa (Dark Chocolate)

5.Numerous studies have shown that cancers develop due to oxidative stress, genetic mutations,hypoxia and reduced apoptotic function. Apoptosis, in simple terms, is a normal cellular activity whereby the body tries to eliminate unwanted cells. Flavonoids play an integral part in promoting apoptotic cellular pathways and preventing cancer cells from proliferating and multiplying.

6.Research shows that flavonoids protect the different organs including the liver and brain from free radical damage. Studies show that flavonoids have protective effects of various liver injuries caused by drug and alcohol usage. Since, they are anti-inflammatory, and antitumor, they protect the hepatocytes from inflammation and fibrosis.

7.Flavonoids are a polyphenol group of compounds that can improve and reduce the symptoms of depression and anxiety. Clinical studies in the past have shown that dietary intake of flavonoids can lower the risk of depression. However, further studies are still anticipated to make substantial proof.

8.Flavonoids are best when naturally consumed as all dark-coloured fruits, vegetables, and green tea contain abundant polyphenolic compounds. It should be included in the routine diet for overall
well-being. However, many flavonoid supplements are out in the market. The best supplements are Cucurmin (Tumeric), Green tea, grape seed extract, Resveratrol, Quercetin, hesperidin and Rutin.

9. Toxicity: Intake of natural flavonoids on a daily diet is usually enough. Sometimes, flavonoids supplements are clinically recommended. However, the risk of flavanoid toxicity exists, if someone takes a huge amount of highly potent supplements. It may affect anaemic and elderly patients as flavonoids may bind with non-heme iron. Flavanoid toxicity may cause liver failure, hemolytic anaemia and male reproductive issues. Recommended daily dose of consumption should be around 400-600mg/day.

10.A healthy routine diet rich in flavonoids will provide all the necessary support to the human body to maintain biological activity, provide anti-oxidant effects, reduce oxidative stress and prevent chronic diseases, maintain cardiovascular health and prevent infectious diseases. The key point is that the food readily available to us contains the most effective flavonoids and antioxidants that fortify our health and immune system, making expensive supplements unnecessary

Thanks for reading.

Peace and love 🙏

Silent Sunday 🍂

by drjurisharma, posted in Blog, healing, health, life, nature, self healing, wellness

Peace and love 🙏

10 facts to know about the MTHFR gene 🙌

by drjurisharma, posted in Blog, body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, healing, health, life, MTHFR, gene mutations, genetic mutations,, wellness
  1. MTHFR, Methylenetetrahydrofolate reductase, is an enzyme found in human chromosome 1,located exactly in the short arm. It plays a significant role in folate and homocysteine (amino acid) metabolism. Studies have shown that individuals with MTHFR deficiencies can have hyperhomocysteinemia
    with homocystinuria.
  2. Research in the past decades has shown that this enzyme plays a key role in homocysteine metabolism. The deficiency of this enzyme is an inborn error of folate metabolism, which is quite
    rare. Yet, several studies have identified this variant as the most common cause of
    hyperhomocysteinemia and a risk factor for many disorders connected to defective homocysteine
    metabolism.

3.Genetic deficiency of MTHFR is rare, but around 50 cases have already been identified worldwide. Symptoms in such individuals are seizures, developmental delay, neurological impairment, gait dysfunction, and a very high level of homocysteine in urine and plasma. Genetic testing of the gene mutation can be done on a saliva swab and blood sample.

4.Genetic mutations are inherited and acquired from the parents. There are 2 forms of mutations that can occur on the MTHFR gene – C677T and A1298C. If one such variant is present, one is less likely to have health issues but if both variants are present, then the individual is likely to have serious health problems.

Depression

5.Health issues associated with people who have two variants of the MTHFR gene are :
Homocystinuria
Alopecia areata
Spina bifida
High blood pressure
Depression or bipolar disorder
certain cancers
Miscarriages

Pregnancy

6.MTHFR affects pregnancy: Research has shown a link between MTHFR gene variants related to repeated miscarriages. It is important to test for MTHFR gene mutation in women who have suffered unexplained recurrent miscarriages or delivered babies with neural tube defects. Extra folate supplementation and blood thinning administration can be useful to prevent such miscarriages.

7.Diagnosis of MTHFR variant cases is done by testing blood samples and saliva swabs in individuals with a very high level of homocysteine in urine and plasma and vitamin deficiencies of folate, choline, vitamin B12, B6 and riboflavin. MTHFR mutation variant people may not have health issues and can be treated by preventive measures of supplementation of folate and vitamin B and lifestyle changes like a nutritious balanced diet, sleep, exercise and avoiding smoking.

Down’s syndrome

8.Babies and children born with MTHFR mutation variants may present with symptoms within the first year of birth. Such children may have ADHD (attention deficit hyperactivity disorder), autism, impairment of sleep, mood disorder, hyperhomocysteinemia, vitamin, folate deficiency, pediatric stroke, spina bifida and Down’s syndrome.

9.Having gene variants is common in the human population. This particular MTHFR variant gene is common in some ethnicities like in Hispanic individuals. Hispanic races have commonly the MTHFR C677T variant. People with such variants are able to process all types of folate. Research shows that 400mcg of folic acid daily can raise the blood folate level irrespective of whether you are MTHFR genotype.

10.Folate and vitamin B are naturally found in many food sources which should definitely be part of the daily diet. Legumes, leafy greens, citrus fruits, broccoli, Brussels sprouts, bananas, avocados and nuts are rich in folate and should be consumed regularly to have normal levels of folate and promote healthy cell division irrespective of gene mutations.

Thanks for reading.

Peace and love 🙏

Silent Sunday🪻

by drjurisharma, posted in Blog, healing, health, life, nature, Purple , flowers, wellness

Peace and love 🙏

New Year wishes, 2025 🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, celebration, healing, health, life, New year, 2025, peace, happiness, love, joy, anger,, New Year, wishes, health, healing, happiness, positivity, fitness, self healing, wellness
‘ Let your hopes, not your hurts shape your future’ Martin Luther King, Jr

It’s time to letting go of whatever that give us pain, hurt, sadness, anger, regrets and guilt as the year comes to an end. 

Grateful that another 365 days are approaching to renew ourselves with positive energy, change, optimism and peace which may uplift us in this life’s journey. 

Wishing to all my lovely, fellow bloggers, may this New Year 2025 bring immense happiness, peace and favorableness to all of us.

Have a wonderful and blessed year ahead.

Peace and love 🙏

10 facts to know about blackheads 🙌

by drjurisharma, posted in Acne, blackheads, pimples, healing, health, life, self healing, Skin, dermatology, facial scars ,facial scrubs , beauty, Skin, hair, Uncategorized, wellness
  1. Blackheads are a type of acne that is common regardless of age group. They are tiny bumps formed on the skin due to clogging of hair follicles, either due to dirt or excess oil deposition on pores. The sebaceous (oil) glands are located all over our body, and they release oil to keep the skin hydrated and prevent drying. Blackheads are formed when these glands are blocked due to excess oil, dirt, pollutants, or the buildup of dead cells.
  2. Blackheads appear as black or dark spots in the skin and can be easily identified. They can appear all over the body but are most commonly seen on the face, nose, cheek, chin, neck, and back. Studies show that blackheads can appear at any age but are found to appear commonly during adolescence, menstruation, stress, or a positive family history of acne.
  3. Studies show clearly that acne and blackheads appear when there is an overproduction of sebum or oil from the sebaceous glands. These sebaceous glands are on the surface of the skin, all over the body. When the pores of the skin surface are blocked due to deposits of dead cells, dirt and excess oil, the pores appear as comedones. When the comedones are opened and the clogged plug becomes oxidised, they appear black or grey in colour hence the name blackheads.

4.Research shows that there are various factors responsible for blackheads as such:

  • Hormonal changes during adolescent years, during menstruation, pregnancy, and taking birth
    control pills.
  • Certain drugs like corticosteroids, lithium, androgens.
  • Production of excess oil or sebum in the body.
  • Improper skin hygiene causes a build-up of bacteria and dirt on the skin.
  • Low levels of vitamin B and vitamin D can cause acne and blackheads.
  • Abnormal formation of keratin, the protein that is present in skin, hair and nails.
  • Genetic predisposition.

5.Blackheads and Sebaceous filaments might look similar on the skin but they are completely different. Sebaceous filaments are normal appendages on the surface of the skin through which sebum travels from the sebaceous glands to the skin surface. They keep the skin hydrated. Whereas blackheads look dark or grey spots on the skin which has plugs on the surface. They are open, dark bumps due to dirt and oil deposits.

6.Whenever blackheads or pimples appear, what people commonly do is that they squeeze them which is completely a wrong idea. This may have the risk of:

  • Infection.
  • Painful acne.
  • Redness and inflammation.
  • Leaving a permanent scar.

7.Blackheads can be effectively prevented, and you can achieve clear skin with the right approach Some of the common ways which can be done to prevent acne and blackheads are:

  • Double cleansing method: First, remove the dirt, oil, and makeup from the skin with an oil-based cleanser. Followed by washing the face with a water-based cleanser or mild facewash.
  • Use facial scrubs regularly to exfoliate the skin and remove the dead cells: A gentle brush, fruit scrubs, and sodium tetraborate decahydrate granules are some less abrasive scrubs which
    can be used.
  • Oatmeal scrubs are effective exfoliative and anti-inflammatory agents suitable for the skin.
  • Pore strips are adhesive strips that are put on the skin and pulled away removing the dirt and excess oil. But, they should be used once or twice a week.
Pore strips

8.Common treatments which can be applied to treat blackheads are:

  • Firstly, squeezing or using some self-removal methods should be completely avoided. These methods are more harmful and worsen the skin condition, leaving a permanent scar.
  • Over-the-counter topical lotion or cleanser can be used: Salicylic acid, Azelaic acid (wheat, barley, other grains naturally contain azelaic acid), Benzoyl peroxide and Retinoids.
  • Tea tree oil is an effective topical agent.

9.If blackheads are persistent or there is skin irritation and inflammation, Dermatologist treatments are necessary. Oral antibiotics, prescription-strength topical agents, chemical peels, microdermabrasion and laser therapy can be used depending on the skin condition.

10. Blackheads, as such are not a serious condition and usually go on their own with routine skin hygiene. Yes, some people suffer from blackheads throughout life. Routinely washing the face with mild face wash, cleansing and moisturizing are necessary. Daily removal of make-up and cosmetic agents at the end of each day is mandatory before following the routine skin cleansing methods. An important tip of the day is keeping your hands away from your face always.

Thanks for sharing.

Peace and love 🙏

8 facts: Giloy, an understated herb 🪴

by drjurisharma, posted in Antioxidant,anti inflammatory, immune boosting, anti cancer, Food, healing, health, herb, Plant, medicinal, Ayurvedic, herbal remedies,, Science, skin, cancer, anti inflammatory, plant, nature, medicine, herb, stomach, abdomen, intestines, wellness

Hello everyone 🙌

  1. Giloy is a herbaceous plant, a climbing shrub, where every part of the plant including the stems has various medicinal benefits. It is mainly grown in the Indian subcontinent, many Asian countries including China, Thailand, Philippines, Myanmar, tropical regions of Australia, and North and South Africa. It prefers a warm tropical climate to grow. Despite its holistic health benefits, it is still not known to many. Scientifically, it is called Tinospora cordifolia.
  2. Giloy is considered an essential herb in Ayurvedic medicine. For centuries, people have been using this herb to treat a long list of health ailments, including infections, fever, asthma, diabetes, gout, diarrhoea, jaundice, urinary problems, and skin conditions.

3.Research studies have found that giloy has many potential compounds like alkaloids, terpenoids, lignans, and steroids which have therapeutic benefits. Studies have also found that the herb contains anti-inflammatory and antioxidant properties which can fight oxidative stress and prevent microbial growth of viruses, bacteria and fungi.

4.Studies show that the entire herbaceous plant including roots, stems, and leaves have medicinal properties. The stems of the plants, especially are potent anti-stress, antioxidant, anti-diabetic, anti-arthritic, anti-allergic, anti-inflammatory, immunomodulatory and anti-cancer properties. Giloy also aids in digestion and gut health.

5.Some studies have shown that the alkaloids found in giloy called berberine work like the medicine metformin and help to reduce blood sugar. It can be effective in controlling blood pressure and reducing the level of LDL( bad cholesterol), hence lowering the risk of heart disease.

6.Lab studies have shown that Giloy can be effective in treating seasonal allergies, and skin conditions like scabies and hay fever. It is effective in controlling asthma. Studies show that it can strengthen the immune system and fight against many pathogens like Klebsiella pneumonia, Pseudomonas, Ecoli and many more.


7.Though Giloy doesn’t have harmful side effects, it is important to use it under expert guidance. The herb can interfere with medications like diabetic medicines, anti-hypertensives, and autoimmune medications. It should be avoided during pregnancy and breastfeeding. Commercially, it is available in capsule form, powder form and tincture. The dosage can be different in different forms depending upon the manufacturer’s preparation. So, it is important to read the label and dosage before buying and using the product.


8.Depending upon the recommended dose on the label of the package and under expert guidance, giloy can be consumed safely with the best outcome. However, in the case of auto-immune diseases like Crohn’s disease, and lupus, the immune system can be overstimulated. Side effects like hypoglycaemia, dizziness or stomach irritation might appear in some individuals. The recommended dosage is about 2-6 gm in the case of adults and less than 500mg in the case of children in either powder or capsule form. Giloy juice can be taken in 2-3 teaspoonfuls with water on an empty stomach in the morning.

Thanks for reading.

Peace and love 🙏

Wordless Wednesday 💛

by drjurisharma, posted in Flower, Wednesday, health, healing,happiness, health, Photography,blogging,blogger

Peace and love 🙏

10 tips of eating healthy🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, detoxification, vegetable,, Fresh, local, produce, healing, health, skin, cancer, anti inflammatory, plant, nature, medicine, herb, wellness

Eating healthy is easier and cheaper… Eating healthy isn’t complicated or fussy. In fact , it is the easiest option if we make it a way of life, a …

10 tips of eating healthy🙌

Butyrate is the latest buzzword! Is it just a hype or the reality? 10 facts 🙌

by drjurisharma, posted in body, health, lifestyle, dietary, exercise, herbs, water, liver, stroke, cancer, hepatitis, brain, butter,dairy,inflammatory,disease,cancer,gut health,, butyrate, dairy, curd, yogurt, detoxification, vegetable,, Food, gut health, gut bacteria, hormones, Gastrointestinal, GI tract, healing, health, life, Science, wellness
Butter is a rich source of butyrate

1.Butyrate is a short-chain fatty acid (SFCA) released during the fermentation of dietary fibres by the gut microbiome. It plays an integral part in supporting gut health and overall well-being. It is an energy source for colonocytes which meet about 70% of their needs. Evidence has shown that this SFCA has tremendous health benefits ranging from immunity support, lowering inflammation, preventing cancers and fighting ageing. Hence, it is the latest buzzword, doing rounds in social media and among advertisers.

2.Recent studies have clearly shown that butyrate plays an important role in both the host and microbial functions in gastrointestinal health. It is a crucial energy source for colonocytes. An optimal level of butyrate promotes and maintains a healthy microbiome level, reduces inflammation, and supports colonocyte functions. It has protective actions against certain intestinal diseases like inflammatory bowel diseases and colon cancer.

3.Butyrate has been shown to prevent the process of inflammation in the gut which can be caused by pathogens, the body’s overreaction (allergic reactions) and oxidative stress. Chronic inflammation in the gut occurs when the gut’s immune system is constantly fighting against these pathogens and free radicals causing the immune health to be weakened. Eating a considerable amount of fibres causes to production of an optimal level of butyrate which helps in protecting against this inflammatory process.

Dietary fiber is a good source of butyrate

4.Studies have shown a great impact of butyrate on obesity. Butyrate is found to lower body weight and decrease lipogenesis in the liver and adipose tissues. It increases fatty acid oxidation and prevents fat accumulation in the body thereby reducing obesity. Butyrate is produced by the fermentation of dietary fibres, so it suppresses the food intake and reduces body weight and fat mass.

5.Animal and cell studies have shown that butyrate increases insulin sensitivity, helps in reducing weight gain, and obesity and promotes weight loss. It helps in maintaining blood sugar levels.

Dairy products

6.Another significant property of butyrate has been shown in research that it promotes cell differentiation. Normally, our cells have the ability to change into any specific type of body cells required like liver cells, heart cells, intestinal cells or blood cells. If the cells are not properly differentiated, then, abnormal growth or tumour appears. Butyrate is found to promote cell differentiation.

7.Studies have shown that butyrate plays an important role in the brain-gut connection. It helps in increasing Brain-Derived Neurotrophic Factor (BDNF), removes toxic byproducts from the brain and prevents brain fog. It promotes neuroplasticity and improves rapid eye movement sleep by 70%.

8.Butyrate helps to regulate the blood pressure level. Studies show that the level of butyrate inversely corresponds to the blood pressure level. A higher butyrate level gives a lower blood pressure level while low butyrate may lead to the rise of high blood pressure.

Leafy veggies

9.Sources of butyrate are :
Dietary fibres like vegetables like garlic, onion, tomatoes, beans, peas, leafy vegetables, broccoli. Fruits like bananas, apples, pears, kiwis.
Whole grains like brown rice, oats, wheat, barley, rye and pulses, legumes.
Dairy sources like milk, cheese, butter, and ghee.
Others like dark chocolate, seeds, nuts, and seawood.
Butyrate supplements are available in the form of sodium, calcium/magnesium butyrate but need to be used as per supervision as they may interfere with other medication.

10.It is important to know that consuming full-fat dairy products like butter, Ghee, cheese, and milk are rich sources of butyrate. However, consuming these products can cause the risk of elevating the level of cholesterol in the body as they are rich in saturated fatty acids too. Therefore, the risk of cardiovascular diseases and obesity may rise. So, the key point to be noted while consuming these products is having them in moderation along with lots of dietary fibre and plenty of water can benefit and maintain the balance.

Thanks for reading.

Peace and love 🙏