1.Butyrate is a short-chain fatty acid (SFCA) released during the fermentation of dietary fibres by the gut microbiome. It plays an integral part in supporting gut health and overall well-being. It is an energy source for colonocytes which meet about 70% of their needs. Evidence has shown that this SFCA has tremendous health benefits ranging from immunity support, lowering inflammation, preventing cancers and fighting ageing. Hence, it is the latest buzzword, doing rounds in social media and among advertisers.
2.Recent studies have clearly shown that butyrate plays an important role in both the host and microbial functions in gastrointestinal health. It is a crucial energy source for colonocytes. An optimal level of butyrate promotes and maintains a healthy microbiome level, reduces inflammation, and supports colonocyte functions. It has protective actions against certain intestinal diseases like inflammatory bowel diseases and colon cancer.
3.Butyrate has been shown to prevent the process of inflammation in the gut which can be caused by pathogens, the body’s overreaction (allergic reactions) and oxidative stress. Chronic inflammation in the gut occurs when the gut’s immune system is constantly fighting against these pathogens and free radicals causing the immune health to be weakened. Eating a considerable amount of fibres causes to production of an optimal level of butyrate which helps in protecting against this inflammatory process.
4.Studies have shown a great impact of butyrate on obesity. Butyrate is found to lower body weight and decrease lipogenesis in the liver and adipose tissues. It increases fatty acid oxidation and prevents fat accumulation in the body thereby reducing obesity. Butyrate is produced by the fermentation of dietary fibres, so it suppresses the food intake and reduces body weight and fat mass.
5.Animal and cell studies have shown that butyrate increases insulin sensitivity, helps in reducing weight gain, and obesity and promotes weight loss. It helps in maintaining blood sugar levels.
6.Another significant property of butyrate has been shown in research that it promotes cell differentiation. Normally, our cells have the ability to change into any specific type of body cells required like liver cells, heart cells, intestinal cells or blood cells. If the cells are not properly differentiated, then, abnormal growth or tumour appears. Butyrate is found to promote cell differentiation.
7.Studies have shown that butyrate plays an important role in the brain-gut connection. It helps in increasing Brain-Derived Neurotrophic Factor (BDNF), removes toxic byproducts from the brain and prevents brain fog. It promotes neuroplasticity and improves rapid eye movement sleep by 70%.
8.Butyrate helps to regulate the blood pressure level. Studies show that the level of butyrate inversely corresponds to the blood pressure level. A higher butyrate level gives a lower blood pressure level while low butyrate may lead to the rise of high blood pressure.
9.Sources of butyrate are :
Dietary fibres like vegetables like garlic, onion, tomatoes, beans, peas, leafy vegetables, broccoli. Fruits like bananas, apples, pears, kiwis.
Whole grains like brown rice, oats, wheat, barley, rye and pulses, legumes.
Dairy sources like milk, cheese, butter, and ghee.
Others like dark chocolate, seeds, nuts, and seawood.
Butyrate supplements are available in the form of sodium, calcium/magnesium butyrate but need to be used as per supervision as they may interfere with other medication.
10.It is important to know that consuming full-fat dairy products like butter, Ghee, cheese, and milk are rich sources of butyrate. However, consuming these products can cause the risk of elevating the level of cholesterol in the body as they are rich in saturated fatty acids too. Therefore, the risk of cardiovascular diseases and obesity may rise. So, the key point to be noted while consuming these products is having them in moderation along with lots of dietary fibre and plenty of water can benefit and maintain the balance.
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3H:health,happiness,healing 